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HGH Human Growth Hormone is a hormone that is naturally produced by the body. It really is synthesized and secreted by skin cells in the anterior pituitary gland located at the bottom of the brain. hGH stimulates many metabolic processes in cells. hGH impacts protein, fat, carbohydrate and mineral metabolism. The major role of HGH is to stimulate the liver to secrete Insulin-like Growth Factor-I (IGF-I). IGF-I stimulates production of cartilage cells, resulting in bone growth and also plays a key role in muscle protein synthesis and organ growth.