Benzoquinone

Idebenone (Ideben) is a chemical derivative of benzoquinone 2, 3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1, 4-benzoquinone and it is a synthetic analogue of Coenzyme Q10.

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Misonac sr is a combination product containing diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties, and misoprostol, a gastrointestinal(GI)mucosal protective prostaglandin E 1 analog. NSAID acts by decreasing the level of Prostaglandins in Cyclo-oxygenase pathway Diclofenac is a potent and highly preferred NSAID it is very effective in relieving pain but the problem is causes gastric ulcer (side effect) Diclofenac decreases the level of both PGE1(Prostaglandin E1)and PGE2 (Prostaglandin E2) Decrease in Prostaglandin E2 decreases pain but decrease in Prostaglandin E1 causes decrease in mucus secretion in stomach. Mucus secretion prevents the stomach cells from gastric acid when mucus secretion is decreased gastric acid damages stomach cell which causes ulcer (that is how diclofenac causes it gastric side effects like ulcer).Misoprostol is a PGE1 (Prostaglandin E1) analogue. Thus by giving Misprostol the level of PGE1 is increased thus mucus secretion loss caused by diclofenac (NSAID) is restored. That is by giving Misoprostol with diclofenac helpful in relieving chronic pain without side effects (ulcer and gastric cell damage).

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Complex Enzyme

Deficiency of the intestinal enzyme Alpha galactosidase and incomplete digestion of complex carbohydrates are the root cause of flatulence.Complex carbohydrates are an essential part of a healthy diet. Complex carbohydrates are an excellent energy source rich in vitamins, minerals and fiber. In our normal diet, we consume lot of complex carbohydrate rich foods everyday.Although complex carbohydrates are a healthy addition to the daily diet, millions of people suffer from varying degrees of uncomfortable gastrointestinal symptoms such as flatulence or excess intestinal gas, bloating, abdominal pain, cramping, GI discomfort etc. due to complex carbohydrate rich foods.

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Folic Acid

Folic acid and methylcobalamin helps in remethylation of homocysteine. In this remethylation pathway a methyl group is transferred from methyltetrahydrofolate (MTHF), the active form of folic acid, to homocysteine. Thereby, homocysteine converted back to methionine.Combining Choline along with Folic acid, Methylcobalamin and Vitamin B6 augments the reduction of fasting homocysteine and offers effective post methionine load homocysteine reduction.Folic acid supplementation offers effective fasting homocysteine reduction. But it did not affect post methionine load homocysteine levels significantly. Choline supplementation, in contrast to folic acid, reduces both fasting levels of homocysteine and after methionine load.

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Vtamin B6 Tablet

Vitamin B6 acts as a co-factor in trans-sulfuration pathway, where homocysteine irreversibly condenses with serine and forms cystathionine. This reaction is catalyzed by the enzyme cystathionine betasynthase. Further, cystathionine is converted into cysteine. This reaction also requires Vitamin B6 as a co-factor.Homocyst, with the combination of choline, folic acid, methylcobalamin and vitamin B6 offers effective fasting and post methionine load homocysteine reduction.

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Methylcobalamin

Vitamin B12, a member of B-Vitamin family is a collective term for a group of cobalt containing compounds known as Corrinoids. The principle Cobalamin are Cynacobalamin, Hydroxycobalamin and the two active co-enzyme form of Vitamin B12 Methylcobalamin and Adenosylcobalamin.

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Rabeprazole

Absorption: the oral bioavailability of Rabeprazole is 52%, Levosulpiride is 30%. Peak plasma concentration Rabeprazole is 3.5 hrs, Levosulpiride is 3hrs, Rabeprazole: It is a PPI. It suppresses gastric acid secretion by inhibiting the gastric H+K+ ATP ase at the secretory surface of the gastric parietal cellPatients with known hypersensitivity to Rabeprazole or Levosulpiride or any excipient used in the formulation.

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Aceclofenac Tablets

Aceclofenac is an orally administered phenylacetic acid derivative with effects on a variety of inflammatory mediators. It is from the class of non-steroidal anti-inflammatory drug (NSAID), related to diclofenac. Through its analgesic and anti-inflammatory properties, aceclofenac provides symptomatic relief in a variety of painful conditions.Paracetamol is a nonopiate, non-salicylate analgesic and antipyretic.1. Aceclofenac directly blocks PGE 2 secretion at the site of inflammation by inhibiting IL-Beta & TNF in the inflammatory cells (Intracellular Action). Aceclofenac has been demonstrated to inhibit cyclooxygenase (COX) activity and to suppress the PGE 2 production by inflammatory cells, which are likely to be a primary source of PGE 2 . Inflammatory cells release IL-1 and TNF, which produce PGE 2 by induction of COX-2. Aceclofenac and 4`-hydroxyaceclofenac penetrate the inflammatory cells like polymorphonuclears, monocytes and rheumatoid synovial cells and get hydrolyzed to the active metabolites diclofenac and 4`-hydroxydiclofenac which inhibit IL-1 and TNF released by the inflammatory cells and therefore suppress production of PGE 2 at the site of inflammation.

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Folic Acid Tablets

Folic acid and methylcobalamin helps in remethylation of homocysteine. In this remethylation pathway a methyl group is transferred from methyltetrahydrofolate (MTHF), the active form of folic acid, to homocysteine. Thereby, homocysteine converted back to methionine.Folic acid supplementation offers effective fasting homocysteine reduction. But it did not affect post methionine load homocysteine levels significantly. Choline supplementation, in contrast to folic acid, reduces both fasting levels of homocysteine and after methionine load.

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Aceclofenac

Aceclofenac is an orally administered phenylacetic acid derivative with effects on a variety of inflammatory mediators. It is from the class of non-steroidal anti-inflammatory drug (NSAID), related to diclofenac. Through its analgesic and anti-inflammatory properties, aceclofenac provides symptomatic relief in a variety of painful conditions.Paracetamol is a nonopiate, non-salicylate analgesic and antipyretic.After oral administration, aceclofenac is rapidly absorbed and the bioavailability is almost 100%. Peak plasma concentrations are reached approximately 1.25 to 3 hours following ingestion. T max is delayed with concomitant food intake whereas the degree of absorption is not influenced.

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Cilnidipine

o blocks both L and N type calcium channel thereby prevents entry of calcium inside the cell and causes vasodilation which is the advantage of cilnidipine over other calcium channel blockers. Whenever there is a vasodilation caused by arterial vasodilators, the sympathetic nervous system is activated and causes tachycardia and vasoconstriction of capillaries.o All CCBs except cilnidipine block only L type, where, these sympathetic over activities are manifested as side effects like urinary albumin excretion and ankle edema.

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Choline Bitartrate

Choline is an essential nutrient and it is a precursor for Betaine. Through oxidation reaction choline gets converted into betaine in the liver. Choline plays an important role in the metabolism of homocysteine and that response to post methionine load is very useful.One of the major commercial salts for supplementation of choline is choline bitartrate. Choline is absorbed from the small intestine by means of transporter proteins in the intestinal cells. Some choline is metabolized in the gut to betaine (trimethylglycine) and trimethylamine, which are also absorbed by the gut. Choline, as well as betaine and trimethylamine, are transported to the liver via portal circulation.In the liver, choline participates in various metabolic reactions, including the formation of CDP-choline, which combines with diacylglycerol to form phosphatidylcholine. Through oxidation, it forms the methyl donor betaine. Trimethylamine, a choline metabolite, is oxidized to trimethylamine oxide in the liver. Choline is transported across the blood-brain barrier by a specific carrier mechanism. Within the brain and other nervous tissue, choline is converted to acetylcholine by the enzyme choline acetyltransferase. Only a small fraction of dietary choline goes to form acetylcholine.

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Methylcobalamin Capsule

Methylcobalamin is one of the two coenzyme forms of vitamin B12. Evidence indicates this form of vitamin B12, in addition to having a theoretical advantage over cyanocobalamin, actually has some metabolic and therapeutic applications not shared by the other forms of vitamin B12. This monograph provides an overview of the pharmacokinetics of methylcobalamin, and will highlight the potential therapeutic relevance for Bell's palsy, cancer, diabetic neuropathy, eye function, heart rate variability, HIV, homocysteinemia, male impotence, and sleep disorders.

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Carbonyl Iron Capsules

HB-4 belongs to the category of Haematinic. Adenosylcobalamin in HB-4 is the active form of Vitamin B12 which plays a vital role in the maturation and synthesis of RBC, Carbonyl Iron in HB4, is the purest form of Iron. Folic Acid and Zinc in HB-4, plays a vital role in anemia.Carbonyl Iron in HB-4, is the most pure form of Iron with better absorption and low incidence of side effects.

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Methyl Salicylate

It has been estimated that from 15% to over 40% of patients taking Oral NSAIDs experience upper gastrointestinal symptoms, higher concentrations of NSAIDs are delivered to the desire site (e.g: Up to 100 times higher NSAIDs occurs in synovial fluid compared to that from NSAID blood level, Additions of Oleum lini, Menthol and Methylsalicylate offers effective counter irritant properties, increase blood supply at the site of application, Low blood levels of the drug reduce the incidence of drug interactions with low skin irritation at the application site.

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Levocetirizine Dihydrochloride Tablets

Levocetirizine is the R-enantiomer of cetirizine. Levocetirizine is an orally active, potent, selective and long acting H1 -histamine receptor antagonist with no anticholinergic activity. No tissue distribution data are available in humans. Levocetirizine is 90% bound to plasma proteins. The distribution of levocetirizine is restrictive, as the volume of distribution is 0.4 lkg.

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Cefpodoxime Proxetil

Cefpodoxime Proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite, cefpodoxime. Following oral administration of 100mg of cefpodoxime Proxetil to fasting subjects, approximately 50% of the administered cefpodoxime dose was absorbed systemically. Over the recommended dosing range (100 to 400mg), approximately 29 to 33% of the administered cefpodoxime dose was excreted unchanged in the urine in 12 hours. There is minimal metabolism of cefpodoxime in vivo.

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Calcium Citrate Maleate Tablets

Calcium (as Calcium Citrate Malate) -1200 mg equivalent to 250mg of elemental calcium, Calcium Citrate Malate is a Metastable complex of calcium, citric acid and malic acid, Vitamin K2-7 carboxylates GCGA proteins and helps in the carrier of calcium. Zinc helps in the proper mineralization of the bone.

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Pyridoxine Hydrochloride

Pyridoxine (Vitamin B6) :It is an essential coenzyme in the conversion of the amino acid tryptophan to niacin. Pyridoxine also plays an important role in the body's metabolism of fats and carbohydrates. The synthesis of unsaturated fatty acids requires pyridoxine. Energy cannot be produced for the cells without this vitamin. pyridoxine deficiency can cause harm to dendrites, dendrites are the parts of nerve cells that carry impulses from one brain cell to another

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Chondroitin Sulfate

Chondroitin Sulphate : Contains large no.of aminosugar, protects the existing cartilages from premature breakdown.

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Saccharomyces Boulardii

Saccharomyces boulardii an immunobiotic stimulates the production of Secretory Immunoglobin A(SIgA) which acts as a first line defense and improves the gastrobarrier immunity.

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Ginkgo Biloba

Betahistine a weak H1 receptor agonist and moderate H3 receptor antagonist increases the blood flow to the vestibular system. Piracetam, a nootropic has been shown to alter the physical properties of the plasma membrane by increasing its fluidity and by protecting the cell against hypoxia and thereby improves the cerebral blood flow. Ginkgo biloba and Vinpocetine have proven excellent efficacy as a nerve specific antioxidants.

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Chondroitin Sulphate

Glucosamine, M S M, Chondroitin Sulphate, Calcium Carbonate, Vitamin D3 which are the essential nutrients synthesised by our body to maintain the bone strength and flexibility of joints. Rebone is the only formulation containing all essential bone nutrients and minerals in single tablet.Chondroitin Sulphate : Contains large no.of aminosugar, protects the existing cartilages from premature breakdown.

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Trimethylamine

One of the major commercial salts for supplementation of choline is choline bitartrate. Choline is absorbed from the small intestine by means of transporter proteins in the intestinal cells. Some choline is metabolized in the gut to betaine (trimethylglycine) and trimethylamine, which are also absorbed by the gut. Choline, as well as betaine and trimethylamine, are transported to the liver via portal circulation.In the liver, choline participates in various metabolic reactions, including the formation of CDP-choline, which combines with diacylglycerol to form phosphatidylcholine. Through oxidation, it forms the methyl donor betaine. Trimethylamine, a choline metabolite, is oxidized to trimethylamine oxide in the liver. Choline is transported across the blood-brain barrier by a specific carrier mechanism. Within the brain and other nervous tissue, choline is converted to.

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Enzyme Medicine

Complex carbohydrates are an essential part of a healthy diet. Complex carbohydrates are an excellent energy source rich in vitamins, minerals and fiber. In our normal diet, we consume lot of complex carbohydrate rich foods everyday.Enzyme replacement therapy with Alpha galactosidase (Galto) is the only right treatment option that treats root cause of flatulence.

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Telmisartan Tablets

o Causes vasodilatation by blocking the AT 1 receptor present on the blood vessels and prevents increase of blood volume by inhibiting aldosterone release.o So telmisartan causes vasodilation and decreases blood volume thereby reducing blood pressure.

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Diacerein

Diacerein directly inhibits InterLeukin-1 synthesis and release in vitro and down modulate InterLeukin-1 induced activities and have been shown to posses disease modifying effect in experimental models of osteoarthritis and in human subjects with finger joint and knee osteoarthritis.Hence, by inhibiting InterLeukin-1 diacerein retards all pathological process initiated in osteoarthritis Diacerein also inhibits InterLeukin-1 induced expression of cartilage degrading enzymes. It also enhances expression of TGF BETA-1 and TGF BETA-2 thus favoring matrix synthesis and turnover in articular chondrocytes, thereby accounting for disease modifying property of diacerein. It also inhibits superoxide production, chemotaxis and phagocytic activity of neutrophils in addition to effect on macrophage migration and phagocytosis. In contrast to NSAIDS diacerein does not inhibit synthesis of prostaglandins; hence no gastro duodenal toxicity has been observed with diacerein .

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Dextrose Injection

Administering thiamine injections as IM or as very slow IV reduces the risks of anaphylactic reactions, 100 200 mg IM or as slow IV with dextrose

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Antioxidant Lycopene

Betacarotene - 10mg, Lycopene - 2000mcgL-Carnitine L-Tartrate - 50mg, Selenium - 60mcg, Most formulation available today claiming to be nutritional therapy are all combination of vitamin and minerals in approved quantities for prophylactic use only. Complete-TD gives all essential antioxidants. Vitamins, minerals in textbook recommended therapeutic dose for nutritional therapy.

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Lactobacillus Capsules

Lactobacillus sporogenes helps in synthesis of B complex vitamins and Vitamin K. It produces enzymes required in the digestion of various carbohydrates, fats, and proteins and also aids in their absorption.The three live bacteria along with Lactobacillus sporogenes colonize in the intestinal tract and do not enter into systemic circulation. hence safe to use, as the ingredients confine themselves only to the lumen of the gastrointestinal tract.

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Voglibose

Voglibose is an alpha-glucosidase inhibitor, it is an oral anti-diabetic drugs used for diabetes mellitus type 2. Alpha-glucosidase inhibitors are act as competitive inhibitors of enzymes needed to digest carbohydrates: specifically alpha-glucosidase enzymes in the brush border of the small intestines. The membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the small intestine. that prevents the digestion of complex carbohydrates (such as starch). Complex carbohydrates are normally converted into simple sugars (monosaccharides) which can be absorbed through the intestine. Hence, alpha-glucosidase inhibitors reduce the impact of complex carbohydrates on blood sugar and decreases the post prandial hyperglycemia in diabetes. Voglibose is slowly and poorly absorbed, and is rapidly excreted. Little metabolism occurs.

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Ferrous Ascorbate

HB4 suspension consists of Ferrous ascorbate the world's most widely recognized reference iron with 4 time's higher absorbtion then any other iron form. Studies shown that Ferrous ascorbate leads to speedy Haemoglobin rise (2.5 - 3.0 gm%) within 30 days and treats iron deficiency anaemia during pregnancy because growing baby needs iron and takes it supply from the mother.Ferrous ascorbate is a stable complex of iron and ascorbate, no oxidation to ferric forms as ascorbate maintains the iron in ferrous form with higher absorbtion leads to less GI disturbance and no interaction with food and can be given any time.

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Levocetirizine Tablets

Montelukast sodium is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene (CysLT 1 ), receptor. Levocetirizine is the R-enantiomer of cetirizine. Levocetirizine is an orally active, potent, selective and long acting H1 -histamine receptor antagonist with no anticholinergic activity.No tissue distribution data are available in humans. Levocetirizine is 90% bound to plasma proteins. The distribution of levocetirizine is restrictive, as the volume of distribution is 0.4 lkg.

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PVC Blister

Exclusive lab model blister packing with cam mechanism for Flat Forming, Sealing & Punching.Designed to pack all customized punches and sizes, Capable to handle complete range of packing requirements, Alu-alu, Blister with PVC-PVDC , Aluminum strips and HDPE packing for stability studies.

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Metformin Tablets

Metformin is an anti hyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial blood glucose. Metformin decreases hepatic glucose production, decrease intestinal absorption of glucose and improves peripheral glucose uptake and utilization.

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Auto Coater

Interchangeable pan having capacity range from 0.5 kg from 3.0 kg, Designed for all types of coating, sugar, Film, enteric coating.Exclusive lab model blister packing with cam mechanism for Flat Forming, Sealing & Punching, Designed to pack all customized punches and sizes.Capable to handle complete range of packing requirements.

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Ginkgo Biloba Capsules

Betahistine a weak H1 receptor agonist and moderate H3 receptor antagonist increases the blood flow to the vestibular system. Piracetam, a nootropic has been shown to alter the physical properties of the plasma membrane by increasing its fluidity and by protecting the cell against hypoxia and thereby improves the cerebral blood flow. Ginkgo biloba and Vinpocetine have proven excellent efficacy as a nerve specific antioxidants.

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Glucosamine Sulphate

Orbone forte is combination of Diacerein and Glucosamine Sulphate.Diacerein is an anthraquinone derivative with chondroprotective action , which belongs to class of Diseases Modifying Osteoarthritis Drugs(DMOADs).Glucosamine is an aminomonosaccharide used for the treatment of osteoarthritis

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Thiamine Hydrochloride

Thiamine, also known as vitamin B1, is a water-soluble, B-complex vitamin necessary for metabolism of proteins, carbohydrates, and fats. Thiamine is involved as a cofactor in numerous enzymes, and is essential to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism.Thiamine deficiency causes, beriberi, which is a disorder typically associated with a diet consisting largely of polished rice. India being large rice consuming country, Indians are very much in risk of thiamine deficiency.

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Montelukast Sodium

Montelukast sodium is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene (CysLT 1 ), receptor. Levocetirizine is the R-enantiomer of cetirizine. Levocetirizine is an orally active, potent, selective and long acting H1 -histamine receptor antagonist with no anticholinergic activity.

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Ordain Health Care Global Pvt Ltd. Sembakkam, Chennai, Tamil Nadu

Our Products

Benzoquinone

Misoprostol

Complex Enzyme

Folic Acid

Vtamin B6 Tablet

Methylcobalamin

Rabeprazole

Aceclofenac Tablets

Folic Acid Tablets

Aceclofenac

Cilnidipine

Choline Bitartrate

Methylcobalamin Capsule

Carbonyl Iron Capsules

Methyl Salicylate

Levocetirizine Dihydrochloride Tablets

Cefpodoxime Proxetil

Calcium Citrate Maleate Tablets

Pyridoxine Hydrochloride

Chondroitin Sulfate

Saccharomyces Boulardii

Ginkgo Biloba

Chondroitin Sulphate

Trimethylamine

Enzyme Medicine

Telmisartan Tablets

Diacerein

Dextrose Injection

Antioxidant Lycopene

Lactobacillus Capsules

Voglibose

Ferrous Ascorbate

Levocetirizine Tablets

PVC Blister

Metformin Tablets

Auto Coater

Ginkgo Biloba Capsules

Glucosamine Sulphate

Thiamine Hydrochloride

Montelukast Sodium

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Ordain Health Care Global Pvt Ltd.
Sembakkam, Chennai, Tamil Nadu