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It s a antitumour antibiotic and finds a useful application in acute leukemia &vin many solid tumours doxorubicin is capable of causing breack in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at phse S phase but toxicity is usually exhibited in g2phase.
It s a antitumour antibiotic and finds a useful application in acute leukemia &vin many solid tumours doxorubicin is capable of causing breack in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at phse S phase but toxicity is usually exhibited in g2phase.
It is an antineoplastic agent.
Indication : Cancer - Breast, non-small cell lung, Prostate, bladder, stomach, esophagus, ovary head and neck.
It is an antineoplastic agent.
Indication : Cancer - Breast, non-small cell lung, Prostate, bladder, stomach, esophagus, ovary head and neck.
It is an antineoplastic agent.
Indication : Cancer - Breast, non-small cell lung, Prostate, bladder, stomach, esophagus, ovary head and neck.
OXALIPLATIN exhibits a cide a spectrum of both in vitro cytotoxicity and in vivo antitumour activity in a variety models. Oxaliplatin also demonstrates in vitro and in vivo activity in various cisplatin resistant models a synergistic cytotoxic action has been observed in comination with fluorouracil both in vitro and in vivo. Studies on the mechanism of action of oxaliplatn, although not completrely elucidated, show that the aqua derivatives resulting from the biotransformation of oxalipaltin inrect with DNA synthesis leading to cytotoxic and antitimour effects.
OXALIPLATIN exhibits a cide a spectrum of both in vitro cytotoxicity and in vivo antitumour activity in a variety models. Oxaliplatin also demonstrates in vitro and in vivo activity in various cisplatin resistant models a synergistic cytotoxic action has been observed in comination with fluorouracil both in vitro and in vivo. Studies on the mechanism of action of oxaliplatn, although not completrely elucidated, show that the aqua derivatives resulting from the biotransformation of oxalipaltin inrect with DNA synthesis leading to cytotoxic and antitimour effects.
it is a diterpenoid compound with anti-tumor activity, it binds specifically to the b tubulin subunit of microtubule and appears to antagonize the disassemble of this cytoskeletal protein.
indication : metastatic ovarian and breast cancer.
It is a diterpenoid compound with anti-tumor activity, it binds specifically to the B tubulin subunit of microtubule and appears to antagonize the disassemble of this cytoskeletal protein.
Indication : Metastatic ovarian and breast cancer.
It inhabits the intracellular phosphorylation of numerous tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinase associated with the epidermal growth factor receptor(EGFR-TK), EGFR is expressed on the cell surface of many normal cell and cancer cells.
Indication : It is indicated as monotherapy for the continued treatment of patients with locally advanced metastatic non-small cell lung cancer after failure of both platinum.
Folinic acid (Leuovorin) is an active coenzyme form and does not need to be reduced by DHF raze inhibitor, its toxicity is not counteracted by folic acid but antagonized by folinic acid.
Indication : Antidote for methoxide & folic acid antagonists.
It is a bisphosphonic acid that is an inhibitor of osteoclastic bone resorption.
Indication : Hypercalcemia of malignancy multiple mycloma.bone from solid tumors.
Ceftriaxone Injection is contraindicated in patients with known hypersensitivity to cephalosporin antibiotics. In patients hypersensitive to penicillin, consider the possibility of allergic cross-reactions. The use of sulbactam is contraindicated in individuals with a history of hypersensitivity reactions to any of the penicillin’s.
Indication : Infections caused by pathogens sensitive to Ceftriaxone Injection.
Ceftriaxone Injection is contraindicated in patients with known hypersensitivity to cephalosporin antibiotics. In patients hypersensitive to penicillin, consider the possibility of allergic cross-reactions. The use of sulbactam is contraindicated in individuals with a history of hypersensitivity reactions to any of the penicillin’s.
Indication : Infections caused by pathogens sensitive to Ceftriaxone Injection.
Meropenem Trihydrate:- It is a synthetic carbapenem Bets-Lactum antibiotic for parentral use. It has a potent bactericidal action against a board spectrum of aerobic and aerobic bacteria.
Indication : Pneumonias, nosocomial pneumonias, intra-abdominal infections, gynaecological infections, skin and skin structure infection, meningitis, septicaemia adult febrile neutropenia.
Meropenem Trihydrate:- It is a synthetic carbapenem Bets-Lactum antibiotic for parentral use. It has a potent bactericidal action against a board spectrum of aerobic and aerobic bacteria.
Indication : Pneumonias, nosocomial pneumonias, intra-abdominal infections, gynaecological infections, skin and skin structure infection, meningitis, septicaemia adult febrile neutropenia.
It is a proton pump inhibitor, i.e, It inhibits specifically and dose proportionally the gastric H+, K+ATPase enzyme which is responsible for acid secretion in the parietal cells of the stomach.
Indication : For the symptomatic improvement and healing of gastrointestinal diseases which require a reduction in acid secretion e.g. Duodenal ulcer, gastric ulcer, Moderate and severe reflux.
Cefepime Is A 4th Generation Cephalosporin Which Inhibits The Final Transpeptidation Step Of Peptidoglycan Synthesis In Bacterial Cell Wall By Binding To One Or More Of The Penicillin-Binding Proteins (PBPs). Absorption: IM Admin: Rapid And Almost Complete Absorption.
Distribution : 16-19% Bound To Plasma Proteins. Volume Of Distribution: 14-20 L; Crosses The Blood Brain Barrier. Penetrates Into Inflammatory Fluid At Concentrations Of About 80% Of Serum Levels.
Vitamins : Are non-energy producing organic compounds essential for normal human metabolism that must be supplied in small quantities in the diet. The importance of vitamins as drugs is primarily in the prevention and treatment of deficiency diseases.
Antioxidants : Contains a mixture of Vitamin C, Vitamin A, Vitamin E, minerals like Copper, Manganese, Zinc and Selenium have synergistic antioxidant effect.
Cyproheptadine Hydrochloride is a serotonin and histamine antagonist with anticholinergic and sedative property. It finds clinical application in stimulating the appetite and growth. Tricholine Citrate contains three molecules of choline. Clinical interest in choline centers on its lipotropic action & its utility in the treatment of fatty infiltration and cirrhosis of liver. Sorbitol is a low calorie sweetening agent.
Indication : Loss of appetite, allergy & pruritis.
Treating infections caused by certain bacteria. Cefixime is a cephalosporin antibiotic. It works by killing sensitive bacteria.
Dosage : The recommended adult dose for otitis media, tonsillitis, pharyngitis, and urinary tract infections is 400 mg once daily or divided and given as 200 mg every 12 hours. Pediatric patients (6 months and older) have a recommended dose of 8 mg/kg/day once daily or in two doses of 4/mg/kg every 12 hours.
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