A drug used to treat women and men with certain types of hormone-receptor positive, HER2-negative breast cancer that is advanced or has spread. It is also being studied in the treatment of other types of cancer. Palbociclib blocks certain proteins, which may help keep cancer cells from growing. It is a type of cyclin-dependent kinase inhibitor. Also called Ibrance.

Palbociclib, sold under the brand name Ibrance among others, is a medication developed by Pfizer for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.

Vindesine, also termed Eldisine, is a semisynthetic vinca alkaloid derived from the flowering plant Catharanthus roseus. Like the natural (e.g. vinblastine and vincristine) and semisynthetic vinca alkaloids (e.g. vinorelbine and vinflunine) derived from this plant, vindesine is an inhibitor of mitosis that is used as a chemotherapy drug. By inhibiting mitosis, vinedsine blocks the proliferation of cells, particularly the rapidly proliferation cells of certain types of cancer. It is used, generally in combination with other chemotherapeutic drugs, in the treatment of various malignancies such as leukaemia, lymphoma, melanoma, breast cancer, and lung cancer

A drug that comes from the bacterium Streptomyces peucetius and is used alone or with other drugs to treat many types of cancer, including leukemia, lymphoma, neuroblastoma, sarcoma, Wilms tumor, and certain cancers of the lung, breast, stomach, ovary, thyroid, and bladder. It is also being studied in the treatment of other types of cancer. Doxorubicin hydrochloride damages the cell’s DNA and may kill cancer cells. It also blocks a certain enzyme needed for cell division and DNA repair. Doxorubicin hydrochloride is a type of anthracycline antibiotic and a type of topoisomerase inhibitor. Doxorubicin is the active ingredient of doxorubicin hydrochloride. Also called Adriamycin and hydroxydaunorubicin.

In the EU doxorubicin pegylated liposomal (as Caelyx) is indicated to treat breast cancer, ovarian cancer, and AIDS-related Kaposi’s sarcoma. It is indicated to treat multiple myeloma in combination with bortezomib.[1] Doxorubicin hydrochloride (as Myocet liposomal) is indicated to treat breast cancer in combination with cyclophosphamide.

Doxorubicin hydrochloride is approved to be used alone or with other drugs to treat:

• Acute lymphoblastic leukemia (ALL).
• Acute myeloid leukemia (AML).
• Breast cancer.
• Gastric (stomach) cancer that is metastatic.
• Hodgkin lymphoma.
• Neuroblastoma that is metastatic.
• Non-Hodgkin lymphoma.
• Non-small cell lung cancer that is metastatic.
• Ovarian cancer that is metastatic.
• Small cell lung cancer that is metastatic.
• Soft tissue and bone sarcomas that are metastatic.
• Thyroid cancer that is metastatic.
• Transitional cell bladder cancer that is metastatic.
• Wilms tumor that is metastatic.
• Doxorubicin hydrochloride is also being studied in the treatment of other types of cancer.

Doxorubicin hydrochloride is also available in a different form called doxorubicin hydrochloride liposome. For more information, see the Drug Information Summary for Doxorubicin Hydrochloride Liposome.

A drug used to treat women and men with certain types of hormone-receptor positive, HER2-negative breast cancer that is advanced or has spread. It is also being studied in the treatment of other types of cancer. Palbociclib blocks certain proteins, which may help keep cancer cells from growing. It is a type of cyclin-dependent kinase inhibitor. Also called Ibrance.

Palbociclib, sold under the brand name Ibrance among others, is a medication developed by Pfizer for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.

Vindesine, also termed Eldisine, is a semisynthetic vinca alkaloid derived from the flowering plant Catharanthus roseus. Like the natural (e.g. vinblastine and vincristine) and semisynthetic vinca alkaloids (e.g. vinorelbine and vinflunine) derived from this plant, vindesine is an inhibitor of mitosis that is used as a chemotherapy drug. By inhibiting mitosis, vinedsine blocks the proliferation of cells, particularly the rapidly proliferation cells of certain types of cancer. It is used, generally in combination with other chemotherapeutic drugs, in the treatment of various malignancies such as leukaemia, lymphoma, melanoma, breast cancer, and lung cancer

A drug that comes from the bacterium Streptomyces peucetius and is used alone or with other drugs to treat many types of cancer, including leukemia, lymphoma, neuroblastoma, sarcoma, Wilms tumor, and certain cancers of the lung, breast, stomach, ovary, thyroid, and bladder. It is also being studied in the treatment of other types of cancer. Doxorubicin hydrochloride damages the cell’s DNA and may kill cancer cells. It also blocks a certain enzyme needed for cell division and DNA repair. Doxorubicin hydrochloride is a type of anthracycline antibiotic and a type of topoisomerase inhibitor. Doxorubicin is the active ingredient of doxorubicin hydrochloride. Also called Adriamycin and hydroxydaunorubicin.

In the EU doxorubicin pegylated liposomal (as Caelyx) is indicated to treat breast cancer, ovarian cancer, and AIDS-related Kaposi’s sarcoma. It is indicated to treat multiple myeloma in combination with bortezomib.[1] Doxorubicin hydrochloride (as Myocet liposomal) is indicated to treat breast cancer in combination with cyclophosphamide.

Doxorubicin hydrochloride is approved to be used alone or with other drugs to treat:

• Acute lymphoblastic leukemia (ALL).
• Acute myeloid leukemia (AML).
• Breast cancer.
• Gastric (stomach) cancer that is metastatic.
• Hodgkin lymphoma.
• Neuroblastoma that is metastatic.
• Non-Hodgkin lymphoma.
• Non-small cell lung cancer that is metastatic.
• Ovarian cancer that is metastatic.
• Small cell lung cancer that is metastatic.
• Soft tissue and bone sarcomas that are metastatic.
• Thyroid cancer that is metastatic.
• Transitional cell bladder cancer that is metastatic.
• Wilms tumor that is metastatic.
• Doxorubicin hydrochloride is also being studied in the treatment of other types of cancer.

Doxorubicin hydrochloride is also available in a different form called doxorubicin hydrochloride liposome. For more information, see the Drug Information Summary for Doxorubicin Hydrochloride Liposome.