Mark Maker Pharma Engineering

Palghar, Maharashtra

Mark Maker Pharma Engineering is a Vasai-Virar (Maharashtra) based Manufacturer and Supplier of high performance Planetary Mixer. The Planetary Mixer is used for mixing pharmaceuticals, foods, chemicals, adhesives, electronics, plastics, pigments, etc. The Planetary Mixer is offered to clients only after laboratory testing & in-plant trial, and as per their specific production requirements.

WorkingPlanetary Mixer is ideal for mixing of wet/dry materials it has a homogeneous mixing action. The planetary motion of the beater enables faster and better mixing of material at a considerably lesser time. It is high shear mixer and is available in variable speed drive, slow speed is used for dry mixing with less dust generation and faster speed for kneading operation during wet granulation portable mixing bowl with top mounted agitator has a dual advantage of material transfer and no risk of gland packing contamination.

Salient Features :

• All contact parts of the mixing bowl and beater are made out of S.S 304 material or S.S 316as per requirements. Scrapping blades can also be provided if     required
• The mixing bowl can be jacketed for electric/steam heating
• Ideal equipment for small batch sizes
• Manual lifting arrangement for agitators up to 50 Lts and motorized lifting arrangement for capacities of 100 Lts and above can be provided
• The top of the mixing bowl has an S.S lid with a charging hole
• The mixing bowl is provided with caster wheels and locking system for easy handling and transportation
• Flame proof motor can be supplied as optional
• Capacity offered 20L to 500L

Application :

• Powder to powder mixing
• Manufacturing of starch paste with steam or thermic fluid electrically heated jacketed with or without a flush bottom valve for discharge
• Dry powder to wet phase mixing for wet granulation

We are counted among reliable Manufacturers and Suppliers of durable FBD Bowl Tipper. The FBD Bowl Tipper is made with accurately dimensioned components that are sourced from reliable vendors. FBD Bowl Tipper, available with us, is known for its reliable functioning and low maintenance. Clients can avail FBD Bowl Tipper from us at very reasonable rates.

Construction & WorkingIt is on equipment operated hydraulically or mechanically for lifting and tipping FBD Bowl loaded with dried granules. Content of the Bowl is transferred smoothly to granulating equipment and through it to a BIN or on IPC container. It provides completely dust free operation and eliminates tedious scooping or manual handling. The process consists of bringing the FBD Bowl beneath the Tipper. The inverted cone of the Tipper is lowered so that the brim flange of the bowl touches the brim flange of the inverted cone. Both ore then clamped together with quick fixing clamps. The whole assembly is raised   hydraulically to the required height and then rotated mechanically to 180 degree on Ms Axis and lowered to a suitable height to align with the receiving container / equipment. The discharge point cone is fitted with an Iris / Butterfly valve by operating which the contents are discharged to Multi Mill or a sifter cum Multi Mill as per the process requirement. The flanged cone and the valve are of S.S.316 /304 malarial, as required. The bottom and the complete drives are covered with highly polished S.S.304 sheets to impart a cGMP finish.

Salient Features :

• Stainless steel lift yoke with integral Gearbox for rotation of discharge cone and  container.
• Discharge cone clamps ore made of stainless steel with ease of secure, clamping design.
• Control cabinet is in powdered coated in M.S. and is  tight, complete with hydraulic power pack and electric control.
• Complete fail safe design.
• Conforms to latest cGMP Standards.
• Discharge cone is fitted with a butterfly valve. The MOC is SS316/304.
• Imported power pack.

Optional Features :

• Free standing unit.
• Hydraulic/Pneumatic/Mechanical design.
• Adjustable stop
• Additional lift column height.
• Double Column For heavier loads.
• Imported power packs.
• Hydraulic arrangement for tilting.
• 1800-SWIVELcolumn.
• Pneumatically actuated waive.
• Single cone for 2 sizes of FBD Bowl with adaptor.

Our company is engaged in manufacturing and supplying feature packed Rapid Mixer Granulator. Rapid Mixer Granulator, offered by us, is ideal for meeting special needs of tablet manufacturing technology. The Rapid Mixer Granulator reduces processing time and performs more homogeneous mixing. There is uniformity of granule size with Rapid Mixer Granulator. Also, the Rapid Mixer Granulator maintains improved hygiene compliant to cGMP norms.

cGMP : Rapid is designed to achieve all the requirements of cGMP –Curent Good Manufacturing Practices. The components can be easily dismantled, cleaned are very effective to check any leakages and cross contamination due to adherents. The bowl and all the components are of highly polished stainless steel with smooth contours and is crevice less.

The Mixing Bowl :

• It is circular with a large diameter and flat base. The top portion of the bowl is conical in shape to assist mixing of cohesive powders.
• Constructed from SS 304/316.
• A large diameter tube surrounds the drive shaft where it enters the base of the bowl. The main drive, shaft seal is on the top of tube and thus well above the     normal powder level. The SHAT SEAL is further improved by AUTOMATIC AIR PURGE.
• The seal housing and drive shaft may be flushed with cleaning water, which is then drained away from the machine through built in drain tubes

Granulator :

• A high speed Granulator (chopper) is inserted horizontally through the wall of the bowl to assist blending of powder and to break the product to granules of     required size.
• The Granulator rotates at two speeds -1500/3000 RPM.
• The Granulator head is of highly polished stainless steel and is easily removable for cleaning.
• The Granulator shaft where it enters the bowl incorporates AIR PURGED SEAL.
• The motor is provided with a removable stainless steel shroud which covers it to meet cGMP norms.

Bottom Discharge Valve :

• It is provided on the bottom, operated by a S.S spindle connected to a pneumatic cylinder. In closed position, the gate is flushed with the contour of the     bowl.
• A cover with removable silicone rubber seal gives unrestricted access into the chute for easy cleaning.
• A safety lock in the form of a limit swith is provided at the discharge port to prevent the valve or the motors to start during the cleaning operation.
• The pneumatic cylinder is covered by a stainless steel shroud to meet cGMP standard.

Improved Processing :

• Uniform distribution of all formulation
• Short mixing and granulation time
• Useful working capacity of upto 80% to 40% of bowl volume.
• Wide range of applications
• Easy scale up & scale down between machine sizes
• Bowl shape design to have no dead spaces

Electrical :

• Mixer granulator is offered in FLAMEROOF and NON-FLAMEROOF constructions. The machine has two panels.
• Main Panels made out of M.S powder coated casing, housing the main contractors, overload replays, MCB’S and the various other control     instrumentations.
• Operating Panel this panel is made in ss304 and comes in 3 options
• Standard operating panel with digital Ammeters, Digital timers and push buttons in Non-flame proof Construction, housed in an ss 304 housing panel.
• Flame proof panel having FLP Ammeters, Analog timers and push buttons.
• PLC panel options can be availed of at the time of ordering

Automation : To achieve constitancy in the product quality it is desirable to minimize/eliminate the human elements in monitoring the operational parameters of the machine including the end point control. it is also desirable to record/store the critical data which may contribute to product quality. The desired operational data can be saved and hard copy (print out) can also be taken out. To incorporate suitable peovision in the system of data required to be reproduced. As a standard, following parameters are recorded.

• Product name
• Product code
• Operator name
• Batch no
• Batch Date
• Batch cycle time
• Dry mixing time
• Wet mixing time
• Granulation time
• End point value
• Various faults if any during cycle

R & D : Rapid mixer granulators can be offered in 10Ltrs, R&D or pilot plants. The process parameters derived in the Lab/Pilot scale machines can be scaled up into production machines. These machines can also be offered with PLC’S 
Documentation :

• Rapid mixer granulators comes along with all documentation like DESIGN QUALIFICATIONS, INSTALLATION QUALIFICATION and OPERATIONAL as a part of standard accompaniment.

• Rapid mixer granulators comes along with all documentation like DESIGN QUALIFICATIONS, INSTALLATION QUALIFICATION and OPERATIONAL as a part of standard accompaniment.

General :

• All internal and External surfaces of mixing Bowl, Mixing Bowl cover, Granulator, Agitator and Discharge Chute are constructed in ss 304/316.
• All Non-Contact parts are in ss 304
• All MS parts are Epoxy painted
• All parts can be easily dismantled and cleaned
• All pneumatics are pre tubed

• All Gaskets are Teflon/silicon  

Optional :

• Jacketed Models
• Vacuum Charging
• Gravity Charging
• Machanical Seals
• Binder Spraying Systems
• CIP/WIP Systems
• Vacuum Drying     
• Scada Solution