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1 Products availableOur Complete range of products are Microcrystalline Cellulose Gel, Microcrystalline Cellulose and Partially Pregelatinized Starch.
Ambicel MBC is water insoluble hydrocolloid. It has got excellent dispersibility in water. Sodium Carboxymethylcellulose is co-processed with partially depolymerized highly purified cellulose to make Ambicel MBC. Incorporation of Sodium Carboxymethylcellulose in the microfibrils of Microcrystalline Cellulose before drying prevents bonding of microfibrils during drying. This action of Sodium Carboxymethylcellulose (CMC) makes Ambicel MBC higly dispersible Gel forming cellulose.
After stirring in water Ambicel MBC forms either colloidal sol or white opaque gel, depending upon concentration. Individual microfibrils of cellulose get separated when dispersed in water and forms gel or colloidal dispersions. In water, with shear, Ambicel MBC forms a three-dimensional matrix comprised of millions of insoluble microcrystals that form a stable, thixotropic gel.
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Applications Of Ambicel MBC By Virtue Of Their Special Qualities Are Given Below
Emulsion Stabilizer | Pharmaceutical & cosmetic creams |
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Foam Stabilizer | Aerosol Foams |
O/W Emulsifier | Pharmaceutical & cosmetic lotions & creams |
Suspending agent | Pharmaceutical & cosmetic suspensions , reconstitutable suspensions |
Body Agent, Stiffener, Opacifier | Pharmaceutical & Cosmetic Creams, Cosmetic Gels, Vaginal Gels |
Microcrystalline Cellulose is an ideal excipient for Pharmaceutical formulations. Product is manufactured in different grades like 101, 102, 112, 200 etc. Material is compliant with IP, BP, USPNF and EP specifications.
R & D Division of Maple Biotech Pvt Ltd., through intensive research developed processess to manufacture versatile Expients like Microcrystalline cellulose, Sodium Starch Glycollate, Croscarmellose Sodium and Calcium Carboxy, Methyl Cellulose. Which have many advantages over other expients like good tablet strength less lubricant Sensitivity and fast disintegration of tablet.
Microcrystalline Cellulose gives superior properties to the tablets Irrespective of tableting technrque like wet ganuatton. direct compression, slugging etc. Tableting technique can be very much simplified with the use 01 Micro crystalline Cellulose.
Mcrocrystalline Cellulose is manufactured from plant cellulose. Cellulose is a natural polymer of glucose molecules havmg 1-4 & linkage. Cellulose constitutes about 40% of plant rnaterial. Cellulose derived from plant as in long chain polymeric form, which ls treated to convert it into short chain. non - fibrous. free flowing powder form. Cellulose undergoes high degree of purification during the manufacturing process. Maple Biotech’s Mlcrocrystalline Cellulose is manufactured under brand name Ambicel is in aggiomerated form of cellulose micro fibrils. Different grades of MCC (Microcrystalline Cellulose ) are produced by virtue of variation in size and density of the agglomerates.
Ambicel :
Mabitab1500 is a new partially pregelatinized maize starch designed for pharmaceutical use. It has been developed as a filler for two-piece hard gelatin capsules. Mabitab1500 is a free-flowing and self-disintegrating powder with high bulk density, making it most suitable for this application. Excellent flow properties and bulk density allow homogenous filling of capsules. It is made from native starch by simple and unique physical modification which ensures rapid disintegration and drug release. Mabitab1500 particles action is well suitable for rapid disintegration and release of the drug from the pharmaceutical preparation. Mabitab1500 is superior starch excipient over Native Starch by virtue of its flow property and disintegration property.
Applications :
Wet Granulation : Mabitab1500 is partially soluble in cold water. It can therefore be employed as a binder-disintegrant in wet granulation, It improves hardness and disintegration time of the tablets. Use level about 15% is recommended in wet granulation tableting
Capsule Filler: Mabitab1500 is cost-effective filler and disintegration aid for hard gelatin capsules. Its physicochemical properties (Flow Property) are well suited to the requirements of an ideal capsule filler. The Mabitab1500 production process results in an appropriate density for this application. compared to native maize starch,
Additional Information:
Packaging Details : As per client requirement
Specifications
TEST | SPECIFICATIONS |
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Description | White or almost white, fine, granular powder, practically insoluble in water, in acetone, in ethanol, in toluene, in dilute acids and in 50 g/l solution of sodium hydroxide |
Identification | Ph Eur, USPNF |
pH | 4.5 to7 ( Ph Eur, USPNF ) |
Residue on Ignition | max 0.5% ( Ph Eur, USPNF ) |
Loss on Drying | Max 14% ( Ph Eur, USPNF ) |
Heavy Metals | Max. 10 ppm |
Loose Bulk Density | 0.50 to 0.60 g/cm3 |
Tapped Bulk Density | 0.60 to 0.70 g/cm3 |
SULPHUR DIOXIDE | Max. 50 ppm |
Oxidising Substances | Negative ( Ph Eur, USPNF ) |
Organic Volatile Impurities | USP |
Residual Solvent | Nil |
Retention on 40 mesh Retention on 200 mesh |
Max. 1% Min. 40% |
Total Aerobic Microbial Count Total Molds and Yeast Count |
max. 1000 cfu/gm ( Ph. Eur /USP) Max. 100 cfu/gm (Ph. Eur / USP) |
E. Coli Salmonella | absent (Pharma Eur/ USP) absent (Pharma Eur/ USP) |