Kapy Pharmaceutical

Ambala Cantt, Ambala, Haryana

Kapy Pharmaceuticals is a well-known name in the pharmaceutical industry. We are engaged as supplier, Exporter and Distributor of wide range of injections. We are known to provide trusted quality in all varieties of injections including Pimtus-T Injection.

Composition of Pimtus-T Injection Cefepime 250 mg+ Tazobactum 31.25 mg

How does this injection work?

Cefepime and Tazobactum, that work together to kill the bacteria that cause infections. Cefipime works by stopping the growth of bacteria. Tazobactum reduces resistance and enhances the activity of Cefipime against bacteria.

Pimtus-T Injection can be used to treat many different bacterial infections. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Cefepime :

Central Nervous System: Headache.

Gastrointestinal: Nausea, vomiting, diarrhea, inflammation of colon, including pseudomembranous colitis, oral candidiasis.

Skin: Rash, itching, hives.

Miscellaneous: Hypersensitivity, including, allergic reaction, toxic epidermal blistering, rash, inflammation or veins, pain or inflammation at injection site; fever.

Why choose Kapy Pharmaceuticals?

We are the most trusted Pimtus-T Injection suppliers. Following are the reasons to choose us:

• finest quality
• certified injections
• reasonable pricing
• bulk supply competence
• easy order procedure
• doorstep delivery
• pharmaceutical products all over the nation

Order with us now!

Kapy Pharmaceuticals is a well-known name in the pharmaceutical industry. We are engaged as supplier, Exporter and Distributor of wide range of injections. We are known to provide trusted quality in all varieties of injections including Emcef-S Injection.

Composition of Emcef-S Injection is Ceftriaxone 250 mg + Sulbactum 125 mg.

How does this injection work?

Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It boosts the activity of β-lactam antibacterials against β-lactamase-producing bacteria.

Significance of using Emcef-S Injection:

Emcef Injection is a prescription medicine which is beneficial to treat certain infections like skin infections, urinary tract infections, lower respiratory tract infections, infections of the female reproductive system, bone and joint infections, long-term middle ear infection, life-threatening outer ear infection and infections within the stomach.

When not to use

Emcef Injectioncannot be used to treat viral infections. These should be used only if it is prescribed.

Why choose Kapy Pharmaceuticals?

We are the most trusted Emcef-S Injection suppliers. Following are the reasons to choose us:

• finest quality
• certified injections
• reasonable pricing
• bulk supply competence
• easy order procedure
• doorstep delivery
• pharmaceutical products all over the nation

Order with us now!

Cefoperazone 500mg + Sulbactam 500mg Salt Information :

Uses of Cefoperazone 500mg + Sulbactam 500mg:Cefoperazone is a third-generation cephalosporin antibiotic. It is used in the treatment of pseudomonas bacterial infections .

Side Effects of Cefoperazone 500mg + Sulbactam 500mg:Rash, skin reactions, fever, eosinophilia, urticaria, and pruritus. Haematological - Slight decreases in Hb conc and haematocrit value. GI effects, diarrhoea or loose stools, nausea, and vomiting. Mild, transient elevations of serum SGOT, SGPT, and alkaline phosphatase concentrations. Renal effects - Transient elevations in BUN and serum creatinine concentrations.

Drug Interactions of Cefoperazone 500mg + Sulbactam 500mg:With aminoglycosides: Concomitant admin may increase risk of nephrotoxicity. With heparin/warfarin: Concurrent use may cause marked hypoprothrombinemia and/or prolonged bleeding time.

Contraindications of Cefoperazone 500mg + Sulbactam 500mg:Hypersensitivity. Known allergy to penicillins.

Mechanism of Action of Cefoperazone 500mg + Sulbactam 500mg:Cefoperazone, a bactericidal antibiotic, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins (PBPs). Sulbactam is a β-lactamase inhibitor and acts primarily by irreversible inactivation of β-lactamases.

Special Precautions for Cefoperazone 500mg + Sulbactam 500mg:Pregnancy, lactation. 

Cefoperazone 1000mg + Sulbactam 500mg Salt Information :

Uses of Cefoperazone 1000mg + Sulbactam 500mg:Cefoperazone is a third-generation cephalosporin antibiotic. It is used in the treatment of pseudomonas bacterial infections .

Side Effects of Cefoperazone 1000mg + Sulbactam 500mg:Rash, skin reactions, fever, eosinophilia, urticaria, and pruritus. Haematological - Slight decreases in Hb conc and haematocrit value. GI effects, diarrhoea or loose stools, nausea, and vomiting. Mild, transient elevations of serum SGOT, SGPT, and alkaline phosphatase concentrations. Renal effects - Transient elevations in BUN and serum creatinine concentrations.

Drug Interactions of Cefoperazone 1000mg + Sulbactam 500mg:With aminoglycosides: Concomitant admin may increase risk of nephrotoxicity. With heparin/warfarin: Concurrent use may cause marked hypoprothrombinemia and/or prolonged bleeding time.

Contraindications of Cefoperazone 1000mg + Sulbactam 500mg:Hypersensitivity. Known allergy to penicillins.

Mechanism of Action of Cefoperazone 1000mg + Sulbactam 500mg:Cefoperazone, a bactericidal antibiotic, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins (PBPs). Sulbactam is a β-lactamase inhibitor and acts primarily by irreversible inactivation of β-lactamases.

Special Precautions for Cefoperazone 1000mg + Sulbactam 500mg:Pregnancy, lactation.

Side Effects
Less Common :

• Hives or welts
• itching
• itching of the vagina or genital area
• pain during sexual intercourse
• redness of the skin
• skin rash
• thick, white vaginal discharge with no odor or with a mild odor

Rare :

• Bloody or cloudy urine
• fever
• greatly decreased frequency of urination or amount of urine
• seizures
• swelling of the feet or lower legs

Incidence Not Known :

• Abdominal or stomach cramps or tenderness
• back, leg, or stomach pains
• black, hairy tongue
• black, tarry stools
• bleeding gums
• blistering, peeling, or loosening of the skin
• bloating
• blood in the stools
• bloody nose
• chest pain
• chills
• clay-colored stools
• cough or hoarseness
• cracks in the skin
• dark urine
• diarrhea
• diarrhea, watery and severe, which may also be bloody
• difficulty with breathing
• difficulty with moving
• difficulty with swallowing
• dizziness
• fast heartbeat
• fever with or without chills
• general body swelling
• general feeling of tiredness or weakness
• headache
• heavier menstrual periods
• increased thirst
• joint or muscle pain
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• light-colored stools
• loss of appetite
• loss of heat from the body
• lower back or side pain
• muscle stiffness
• nausea or vomiting
• pain
• pain, swelling, or redness in the joints
• painful or difficult urination
• pale skin
• pinpoint red spots on the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rash
• red skin lesions, often with a purple center
• red, irritated eyes
• red, swollen skin
• scaly skin
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• swollen glands
• tightness in the chest
• troubled breathing with exertion
• unpleasant breath odor
• unusual bleeding or bruising
• unusual tiredness or weakness
• unusual weight loss
• upper right abdominal or stomach pain
• vomiting of blood
• white patches in the mouth or throat or on the tongue
• white patches with diaper rash
• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking amoxicillin / clavulanate:

Symptoms of Overdose :

• Abdominal or stomach pain
• cloudy urine
• diarrhea
• greatly decreased frequency of urination or amount of urine
• sleepiness

Some side effects of amoxicillin / clavulanate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence Not Known :

• Burning feeling in the chest or stomach
• indigestion
• redness, swelling, or soreness of the tongue
• stomach upset
• swelling or inflammation of the mouth

Inactive Ingredients

• Tablets- Colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide. Each tablet of AUGMENTIN contains 0.63 mEq potassium.
• Powder for Oral Suspension- Colloidal silicon dioxide, flavorings, xanthan gum, and one or more of the following: hypromellose, mannitol, silica gel, silicon dioxide, succinic acid, sodium saccharin, and aspartame. [see WARNINGS AND PRECAUTIONS

• Chewable Tablets- Colloidal silicon dioxide, flavorings, magnesium stearate, mannitol, and one or more of the following: D&C Yellow No. 10, FD&C Red No. 40, glycine, sodium saccharin, and aspartame. [see WARNINGS AND PRECAUTIONS
  • Each 125-mg chewable tablet and each 5 mL of reconstituted 125/5 mL oral suspension of AUGMENTIN contains 0.16 mEq potassium
  • Each 250-mg chewable tablet and each 5 mL of reconstituted 250/5 mL oral suspension of AUGMENTIN contains 0.32 mEq potassium
  • Each 200-mg chewable tablet and each 5 mL of reconstituted 200/5 mL oral suspension of AUGMENTIN contains 0.14 mEq potassium
  • Each 400-mg chewable tablet and each 5 mL of reconstituted 400/5 mL oral suspension of AUGMENTIN contains 0.29 mEq potassium

Amoxycillin 1000mg + Clavulanic acid 200mg Salt Information :

Uses of Amoxycillin 1000mg + Clavulanic acid 200mg:Amoxicillin is a penicillin antibiotic that fights bacteria. Amoxicillin is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, gonorrhea, and infections of the ear, nose, throat, skin, or urinary tract.

Side Effects of Amoxycillin 1000mg + Clavulanic acid 200mg:Nausea, vomiting, diarrhoea, indigestion, rash and urticaria, candida superinfection. Potentially Fatal: Anaphylactic reaction with CV collapse esp with parenteral use.

Drug Interactions of Amoxycillin 1000mg + Clavulanic acid 200mg:Allopurinol may reduce renal tubular secretion of amoxicillin thus increasing the serum levels of amoxicillin. Concurrent use may reduce the efficacy of oral contraceptives.

Contraindications of Amoxycillin 1000mg + Clavulanic acid 200mg:Penicillin allergy.

Mechanism of Action of Amoxycillin 1000mg + Clavulanic acid 200mg:Clavulanic acid has a high affinity for and binds to certain β-lactamases that generally inactivate amoxicillin by hydrolyzing its β-lactam ring. Combining clavulanate potassium with amoxicillin extends the antibacterial spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin and other penicillins and cephalosporins. Distribution: Protein binding: About 25% (Clavulanic acid); about 18% (Amoxicillin). Amoxicillin distributes readily into most body tissues and fluids except the brain and spinal fluid. Excretion: Half-life after oral admin: 1.3 hr (Amoxicillin); 1 hr (Clavulanic acid). About 50-70% of amoxicillin and 25-40% of clavulanic acid are excreted unchanged in urine during the 1st 6 hr after admin.

Special Precautions for Amoxycillin 1000mg + Clavulanic acid 200mg:History of allergy especially to cephalosporins, infectious mononucleosis, severe renal impairment.

Ceftriaxone 500mg + Sulbactam 250mg Salt Information :

Side Effects of Ceftriaxone 500mg + Sulbactam 250mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase. GI effects; pseudomembranous colitis; hematologic effects; hypersensitivity reactions; CNS disturbances; hypertension; chest pain; edema; moniliasis; rhinitis; dyspnea; hypotension; ileus; syncope; local Inj site reactions; rigors. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 500mg + Sulbactam 250mg:Probenecid; aminoglycosides; vecuronium, methotrexate; oral anticoagulants; heparin. Potentially Fatal: Disulfiram-like reaction with alcohol. Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 500mg + Sulbactam 250mg:Hypersensitivity to cephalosporins and β-lactamase inhibitors.

Mechanism of Action of Ceftriaxone 500mg + Sulbactam 250mg:Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It enhances the activity of β-lactam antibacterials against β-lactamase-producing bacteria. Distribution: Ceftriaxone: 98% bound to plasma proteins; crosses the blood brain barrier. Tazobactam: About 30% bound to plasma proteins; widely distributed to tissues and body fluids. Excretion: Ceftriaxone: Elimination half-life is about 8.7 hr; 33-67% removed as unchanged drug. Tazobactam: Removed mainly via kidneys with 80% of an administered dose as unchanged drug.

Special Precautions for Ceftriaxone 500mg + Sulbactam 250mg:History of penicillin allergy; lactation. Consider possibility of pseudomembranous colitis in patients who present with diarrhoea subsequent to the admin of antibacterial agents. Monitor prothrombin time in patients with impaired vit K synthesis or low vit K stores during treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms. Caution in patients with a history of GI disease, especially colitis. Discontinue treatment in patients who develop signs/symptoms suggestive of gallbladder disease. Not to be used in hyperbilirubinemic neonates, especially prematures.

Ceftriaxone 1000mg + Sulbactam 500mg Salt Information :

Side Effects of Ceftriaxone 1000mg + Sulbactam 500mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase. GI effects; pseudomembranous colitis; hematologic effects; hypersensitivity reactions; CNS disturbances; hypertension; chest pain; edema; moniliasis; rhinitis; dyspnea; hypotension; ileus; syncope; local Inj site reactions; rigors. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 1000mg + Sulbactam 500mg:Probenecid; aminoglycosides; vecuronium, methotrexate; oral anticoagulants; heparin. Potentially Fatal: Disulfiram-like reaction with alcohol. Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 1000mg + Sulbactam 500mg:Hypersensitivity to cephalosporins and β-lactamase inhibitors.

Mechanism of Action of Ceftriaxone 1000mg + Sulbactam 500mg:Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It enhances the activity of β-lactam antibacterials against β-lactamase-producing bacteria. Distribution: Ceftriaxone: 98% bound to plasma proteins; crosses the blood brain barrier. Tazobactam: About 30% bound to plasma proteins; widely distributed to tissues and body fluids. Excretion: Ceftriaxone: Elimination half-life is about 8.7 hr; 33-67% removed as unchanged drug. Tazobactam: Removed mainly via kidneys with 80% of an administered dose as unchanged drug.

Special Precautions for Ceftriaxone 1000mg + Sulbactam 500mg:History of penicillin allergy; lactation. Consider possibility of pseudomembranous colitis in patients who present with diarrhoea subsequent to the admin of antibacterial agents. Monitor prothrombin time in patients with impaired vit K synthesis or low vit K stores during treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms. Caution in patients with a history of GI disease, especially colitis. Discontinue treatment in patients who develop signs/symptoms suggestive of gallbladder disease. Not to be used in hyperbilirubinemic neonates, especially prematures.

Meropenem 250mg Salt Information :

Side Effects of Meropenem 250mg:Diarrhoea, nausea, vomiting, abdominal pain; headache; constipation; rash, pruritus, uticaria; apnoea; phlebitis, thrombophlebitis, swelling and pain at inj site; disturbances in LFTs (may cause increases in serum transaminases, alkaline phosphatase, lactic dehydrogenase). Rarely: erythema multiforme; eosinophilia, thrombocytopenia, leucopenia, neutropenia; seizures and CNS effects reported in patients with underlying CNS disorders or renal impairment. Potentially Fatal: Anaphylaxis; pseudomembranous colitis; Stevens-Johnsons sydrome.

Drug Interactions of Meropenem 250mg:Serum levels may be increased by probenecid. May reduce serum valproic acid levels; sub-therapeutic levels may be reached in some patients.

Contraindications of Meropenem 250mg:Hypersensitivity.

Mechanism of Action of Meropenem 250mg:Meropenem is a carbapenem that works by inhibiting the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls by binding to one or more of the penicillin-binding proteins (PBPs), thus inhibiting cell wall biosynthesis resulting to bacterial lysis. Distribution: Widely distributed into body tissues and fluids; CSF; bile. Metabolism: More stable to renal dehydropeptidases; converted to one inactive metabolite. Excretion: Via urine within 12 hr by glomerular filtration and tubular secretion (70% unchanged). Elimination half-life: 1 hr. Removed by dialysis.

Special Precautions for Meropenem 250mg:History of hypersensitivity to carbapenem, pencillins or other β-lactam antibiotics; infants <3 mth; renal insufficiency; neurological disorders; pregnancy, lactation. Not recommended for use in MRSA.

DescriptionMeropenem 500 MG Injection is a broad spectrum antibiotic used to treat a variety of conditions caused by bacteria such as infections of stomach, brain, and lungs. It should be used with caution in patients with central nervous system disorders.

Uses of Meropenem 500 MG Injection
What is it prescribed for?

• Bacterial Meningitis : Meropenem 500 MG Injection is used in the treatment of Meningitis which is an inflammation of the protective membranes that surround the brain and spinal cord caused by Streptococcus pneumoniae and Neisseria meningitidis.
• Skin and structure Infection : Meropenem 500 MG Injection is used in the treatment of skin and structure infections like cellulitis, wound infections caused by Streptococcus pyogenes and Staphylococcus aureus.
• Intra-abdominal Infection : Meropenem 500 MG Injection is used in the treatment of intra-abdominal infections like caused by Escherichia coli and Klebsiella.
• Pneumonia : Meropenem 500 MG Injection is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

Side effects
Major & minor side effects for Meropenem 500 MG Injection

• Swelling and redness at the injection site
• Fever
• Confusion
• Fast heartbeat
• Skin rash
• Black or tarry stools
• Decreased urine output
• Diarrhea
• Constipation
• Body pain
• Acid or sour stomach
• White patches in the mouth or on the tongue

DescriptionMeropenem 1000 MG Injection is a broad spectrum antibiotic used to treat a variety of conditions caused by bacteria such as infections of stomach, brain, and lungs. It should be used with caution in patients with central nervous system disorders.

Uses of Meropenem 1000 MG Injection
What is it prescribed for?

• Bacterial Meningitis : Meropenem 1000 MG Injection is used in the treatment of Meningitis which is an inflammation of the protective membranes that surround the brain and spinal cord caused by Streptococcus pneumoniae and Neisseria meningitidis.
• Skin and structure Infection : Meropenem 1000 MG Injection is used in the treatment of skin and structure infections like cellulitis, wound infections caused by Streptococcus pyogenes and Staphylococcus aureus.
• Intra-abdominal Infection : Meropenem 1000 MG Injection is used in the treatment of intra-abdominal infections like caused by Escherichia coli and Klebsiella.
• Pneumonia : Meropenem 1000 MG Injection is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

Side effects
Major & minor side effects for Meropenem 1000 MG Injection

• Swelling and redness at the injection sitesevere
• Feversevere
• Confusionsevere
• Fast heartbeatsevere
• Skin rashsevere
• Black or tarry stoolssevererare
• Decreased urine outputsevererare
• Diarrheasevererare
• Constipation
• Body pain
• Acid or sour stomachrare
• White patches in the mouth or on the tongue

DescriptionCeftriaxone 250 MG Injection is used to treat a variety of conditions such as urinary tract infections, infection of the ears, lungs and meningitis caused by bacteria. It should not be used with calcium-containing intravenous solutions.

Uses of Ceftriaxone 250 MG Injection
What is it prescribed for?

• Bacterial Meningitis : Ceftriaxone 250 MG Injection is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord. This infection may be caused by Streptococcus pneumoniae or Neisseria meningitidis.
• Bacterial Septicemia : Ceftriaxone 250 MG Injection is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.
• Gonococcal Infection : Ceftriaxone 250 MG Injection is used in the treatment of gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.
• Urinary Tract Infection : Ceftriaxone 250 MG Injection is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.
• Pneumonia : Ceftriaxone 250 MG Injection is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
• Bone and joint infections : Ceftriaxone 250 MG Injection is used in the treatment of bone and joint infections such as septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.
• Skin and structure Infection : Ceftriaxone 250 MG Injection is used in the treatment of Skin and structure infections such as cellulitis, wound infection and cutaneous abscesses caused by Streptococcus pyogenes and Staphylococcus aureus.

Side effects
Major & minor side effects for Ceftriaxone 250 MG Injection

• Black or tarry stools
• Chest pain
• Fever
• Difficulty or painful urination
• Sore throat
• Diarrhea
• Abdominal pain
• Dizziness
• Swelling of face, lips, eyelids, tongue, hands and feet
• Acid or sour stomach
• Change in taste
• Excessive air or gas in stomach

Ceftriaxone 500mg Salt Information :

Side Effects of Ceftriaxone 500mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase; leucopenia, neutropenia. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 500mg:Disulfiram-like reaction with alcohol. Potentially Fatal: Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 500mg:Hypersensitivity to cephalosporins; hyperbilirubinaemic neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hr of ceftriaxone administration due to risk of calcium-ceftriaxone precipitate formation.

Mechanism of Action of Ceftriaxone 500mg:Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Absorption: Peak plasma concentrations after 2 hr (IM). Distribution: Distributed widely into body tissues and fluids; CSF (therapeutic concentrations). Crosses the placenta and enters breast milk; bile (high concentrations). Protein-binding: 85-95%. Excretion: Via the urine (40-65% as unchanged); via the bile to the faeces (remainder as unchanged and microbiologically inactive compounds); 6-9 hr (elimination half-life).

Special Precautions for Ceftriaxone 500mg:History of penicillin allergy; severe renal impairment; pregnancy and lactation; superinfection.

DescriptionCeftriaxone 1000 MG Injection is used to treat a variety of conditions such as urinary tract infections, infection of the ears, lungs and meningitis caused by bacteria. It should not be used with calcium-containing intravenous solutions.

Uses of Ceftriaxone 1000 MG Injection
What is it prescribed for?

• Bacterial Meningitis : Ceftriaxone 1000 MG Injection is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord. This infection may be caused by Streptococcus pneumoniae or Neisseria meningitidis.
• Bacterial Septicemia : Ceftriaxone 1000 MG Injection is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.
• Gonococcal Infection : Ceftriaxone 1000 MG Injection is used in the treatment of gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.
• Urinary Tract Infection : Ceftriaxone 1000 MG Injection is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.
• Pneumonia : Ceftriaxone 1000 MG Injection is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
• Bone and joint infections : Ceftriaxone 1000 MG Injection is used in the treatment of bone and joint infections such as septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.
• Skin and structure Infection :  Ceftriaxone 1000 MG Injection is used in the treatment of Skin and structure infections such as cellulitis, wound infection and cutaneous abscesses caused by Streptococcus pyogenes and Staphylococcus aureus.

Side effects
Major & minor side effects for Ceftriaxone 1000 MG Injection

• Black or tarry stoolssevere
• Chest painsevere
• Feversevere
• Difficulty or painful urinationsevere
• Sore throatsevere
• Diarrheasevere
• Abdominal painsevererare
• Dizzinesssevererare
• Swelling of face, lips, eyelids, tongue, hands and feet severerare
• Acid or sour stomachsevererare
• Change in tasterare
• Excessive air or gas in stomach

Side Effects :

Redness/pain/swelling at the injection site, headache, nausea, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication may rarely increase the risk of a serious lung infection (e.g., pneumonia). Tell your doctor immediately if any of these symptoms of lung infection occur: difficult/painful breathing, cough, fever, unusual tiredness.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

How to Use :

This medication is given by injection into a vein by a health care professional. Health care professionals must follow all the manufacturer's instructions for properly mixing and giving this drug. If you have any questions about using this medication properly, consult your doctor or pharmacist.The dosage is based on your medical condition and response to treatment.Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.Tell your doctor if your condition persists or worsens.

Uses :

Pantoprazole is a proton pump inhibitor (PPI) used to treat stomach and throat problems related to extra stomach acid (e.g., esophagitis, ulcers). Decreasing extra stomach acid can help relieve symptoms such as heartburn, difficulty swallowing, persistent cough, and trouble sleeping. It can also prevent serious problems caused by acid damage to your digestive system (e.g., ulcers, cancer of the esophagus).The injection form of this drug is used for a short time when you cannot take the medication by mouth. When possible, your doctor should switch you to the form that is taken by mouth. Pantoprazole works by blocking acid production in the stomach.

Ceftriaxone 250mg + Tazobactam 31.25mg Salt Information :

Side Effects of Ceftriaxone 250mg + Tazobactam 31.25mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase. GI effects; pseudomembranous colitis; hematologic effects; hypersensitivity reactions; CNS disturbances; hypertension; chest pain; edema; moniliasis; rhinitis; dyspnea; hypotension; ileus; syncope; local Inj site reactions; rigors. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 250mg + Tazobactam 31.25mg:Probenecid; aminoglycosides; vecuronium, methotrexate; oral anticoagulants; heparin. Potentially Fatal: Disulfiram-like reaction with alcohol. Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 250mg + Tazobactam 31.25mg:Hypersensitivity to cephalosporins and β-lactamase inhibitors.

Mechanism of Action of Ceftriaxone 250mg + Tazobactam 31.25mg:Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It enhances the activity of β-lactam antibacterials against β-lactamase-producing bacteria. Distribution: Ceftriaxone: 98% bound to plasma proteins; crosses the blood brain barrier. Tazobactam: About 30% bound to plasma proteins; widely distributed to tissues and body fluids. Excretion: Ceftriaxone: Elimination half-life is about 8.7 hr; 33-67% removed as unchanged drug. Tazobactam: Removed mainly via kidneys with 80% of an administered dose as unchanged drug.

Special Precautions for Ceftriaxone 250mg + Tazobactam 31.25mg:History of penicillin allergy; lactation. Consider possibility of pseudomembranous colitis in patients who present with diarrhoea subsequent to the admin of antibacterial agents. Monitor prothrombin time in patients with impaired vit K synthesis or low vit K stores during treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms. Caution in patients with a history of GI disease, especially colitis. Discontinue treatment in patients who develop signs/symptoms suggestive of gallbladder disease. Not to be used in hyperbilirubinemic neonates, especially prematures.

Ceftriaxone 500mg + Tazobactam 62.5mg Salt Information :

Side Effects of Ceftriaxone 500mg + Tazobactam 62.5mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase. GI effects; pseudomembranous colitis; hematologic effects; hypersensitivity reactions; CNS disturbances; hypertension; chest pain; edema; moniliasis; rhinitis; dyspnea; hypotension; ileus; syncope; local Inj site reactions; rigors. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 500mg + Tazobactam 62.5mg:Probenecid; aminoglycosides; vecuronium, methotrexate; oral anticoagulants; heparin. Potentially Fatal: Disulfiram-like reaction with alcohol. Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 500mg + Tazobactam 62.5mg:Hypersensitivity to cephalosporins and β-lactamase inhibitors.

Mechanism of Action of Ceftriaxone 500mg + Tazobactam 62.5mg:Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It enhances the activity of β-lactam antibacterials against β-lactamase-producing bacteria. Distribution: Ceftriaxone: 98% bound to plasma proteins; crosses the blood brain barrier. Tazobactam: About 30% bound to plasma proteins; widely distributed to tissues and body fluids. Excretion: Ceftriaxone: Elimination half-life is about 8.7 hr; 33-67% removed as unchanged drug. Tazobactam: Removed mainly via kidneys with 80% of an administered dose as unchanged drug.

Special Precautions for Ceftriaxone 500mg + Tazobactam 62.5mg:History of penicillin allergy; lactation. Consider possibility of pseudomembranous colitis in patients who present with diarrhoea subsequent to the admin of antibacterial agents. Monitor prothrombin time in patients with impaired vit K synthesis or low vit K stores during treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms. Caution in patients with a history of GI disease, especially colitis. Discontinue treatment in patients who develop signs/symptoms suggestive of gallbladder disease. Not to be used in hyperbilirubinemic neonates, especially prematures.

Ceftriaxone 1000mg + Tazobactam 125mg Salt Information :

Side Effects of Ceftriaxone 1000mg + Tazobactam 125mg:Superinfection; anaphylaxis; diarrhoea; local reactions; blood dyscrasias; rash, fever, pruritus; elevated transaminases and alkaline phosphatase. GI effects; pseudomembranous colitis; hematologic effects; hypersensitivity reactions; CNS disturbances; hypertension; chest pain; edema; moniliasis; rhinitis; dyspnea; hypotension; ileus; syncope; local Inj site reactions; rigors. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions of Ceftriaxone 1000mg + Tazobactam 125mg:Probenecid; aminoglycosides; vecuronium, methotrexate; oral anticoagulants; heparin. Potentially Fatal: Disulfiram-like reaction with alcohol. Nephrotoxicity with aminoglycosides and furosemide.

Contraindications of Ceftriaxone 1000mg + Tazobactam 125mg:Hypersensitivity to cephalosporins and β-lactamase inhibitors.

Mechanism of Action of Ceftriaxone 1000mg + Tazobactam 125mg:Ceftriaxone interferes with the biosynthesis of the peptidoglycan component of the bacterial cell way by binding to and inactivating penicllin-binding proteins (PBPs). Tazobactam is a penicillanic acid sulfone derivative with β-lactamase inhibitory properties. It enhances the activity of β-lactam antibacterials against β-lactamase-producing bacteria. Distribution: Ceftriaxone: 98% bound to plasma proteins; crosses the blood brain barrier. Tazobactam: About 30% bound to plasma proteins; widely distributed to tissues and body fluids. Excretion: Ceftriaxone: Elimination half-life is about 8.7 hr; 33-67% removed as unchanged drug. Tazobactam: Removed mainly via kidneys with 80% of an administered dose as unchanged drug.

Special Precautions for Ceftriaxone 1000mg + Tazobactam 125mg:History of penicillin allergy; lactation. Consider possibility of pseudomembranous colitis in patients who present with diarrhoea subsequent to the admin of antibacterial agents. Monitor prothrombin time in patients with impaired vit K synthesis or low vit K stores during treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms. Caution in patients with a history of GI disease, especially colitis. Discontinue treatment in patients who develop signs/symptoms suggestive of gallbladder disease. Not to be used in hyperbilirubinemic neonates, especially prematures.

Cefepime 1000mg + Tazobactam 125mg Salt Information :

Uses of Cefepime 1000mg + Tazobactam 125mg:Cefepime is a broad spectrum antibiotic used in various baterial infections like gastritis , pneumonia , urinary tract infections and kidney infections .

Side Effects of Cefepime 1000mg + Tazobactam 125mg:Positive Coombs' test without haemolysis; rash, pruritus; diarrhoea, nausea, vomiting; fever, headache; pain and erythema at inj site; agranulocytosis; anaphylactic shock; leucopenia; neutropenia; thrombocytopenia.

Drug Interactions of Cefepime 1000mg + Tazobactam 125mg:Increased effect with high-dose probenecid; increased nephrotoxic potential with aminoglycosides.

Contraindications of Cefepime 1000mg + Tazobactam 125mg:Hypersensitivity to cefepime or other cephalosporins.

Mechanism of Action of Cefepime 1000mg + Tazobactam 125mg:Cefepime is a 4th generation cephalosporin which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs). Absorption: IM admin: Rapid and almost complete absorption. Distribution: 16-19% bound to plasma proteins. Volume of distribution: 14-20 L; crosses the blood brain barrier. Penetrates into inflammatory fluid at concentrations of about 80% of serum levels. Metabolism: Minimally hepatic. Excretion: Plasma half-life: 2 hr. Excreted in urine with 85% as unchanged drug.

Special Precautions for Cefepime 1000mg + Tazobactam 125mg:Renal impairment; history of penicillin or cephalosporin allergy; lactation, pregnancy. Caution when used in patients with history of GI diseases, especially colitis. May decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, renal or hepatic impairment and those on prolonged treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms, resulting in superinfection. Consider the possibility of Clostridium difficile associated diarrhoea in patients who present with diarrhoea after treatment. Caution when used in patients with a history of seizures.