Jai Radhe Sales

Ellisbridge, Ahmedabad, Gujarat

Bismuth subsalicylate displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic. It can also cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in their saliva and gastrointestinal tract. This discoloration is temporary and harmless

IUPAC NAME:(17R, 21ß)-ajmalan- 17, 21-diol OR (1R, 9R, 10S, 13R, 14R, 16S, 18S)- 13-ethyl- 8-methyl- 8, 15-diazahexacyclo [14.2.1.01, 9.02, 7.010, 15.012, 17] nonadeca- 2(7), 3, 5-triene- 14, 18-diol. SYNONYMS:Ritmos;Ajmalin;Ignazin;Takycor; Aritmina;AJMALINE; Rytmalin;Siddiqui;Tajmalin;Cartagine. DESCRIPTION:This compound belongs to the ajmaline-sarpagine alkaloids. These are organic compounds containing either of the indole structures ajmaline, sarpagine, or derivative thereof. An found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments. The drug has been very popular in some countries for the treatment of atrial fibrillation in patients with the Wolff–Parkinson–White syndrome and in well tolerated monomorphic ventricular tachycardias. It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. In these cases, abnormal prolongation of the HV interval has been taken as a proof for infrahisian conduction defects tributary for permanent pacemaker implantation.