Franco-Indian Pharmaceuticals Private Limited

Mahalaxmi, Mumbai, Maharashtra

Three of the major biochemical pathways implicated in the pathogenesis of hyperglycemia induced vascular damage (the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG) protein kinase C (PKC) pathway are activated by increased availability of the glycolytic metabolites glyceraldehyde-3-phosphate and fructose-6-phosphate. The ability of benfotiamine to inhibit three major pathways simultaneously might be clinically useful in preventing the development and progression of diabetic complications.

GLYCIPHAGE® contains the active ingredient Metformin Hydrochloride, an oral anti-diabetic drug belonging to the biguanide class of molecules that decrease glucose production by the liver.

Hyperuricemia is associated with several cardiovascular, metabolic and renal co-morbidities that may complicate its management. There is a growing evidence that hyperuricemia is an independent risk factor for hypertension, Myocardial Infarction (MI), Coronary Heart Disease (CHD), stroke, metabolic syndrome and its components and Chronic Kidney Disease (CKD).