CSC Pharmaceuticals International

Gamdevi, Mumbai, Maharashtra

Our organization is engaged in providing highly effective Dacotin 100mg, which is used to cure Colorectal Cancer. This drug has active component Oxaliplatin, which belongs to platinum-based drugs and is usually classified as alkylating agents. Further, this drug can be obtained in strength of 100 mg intravenous infusion. Clients can avail this Dacotin 100mg at industry leading prices from us.

Uromitexan (mesna) New Zealand Data Sheet Uromitexan Data Sheet 7 August 2014 Page 1 of 14 Baxter UROMITEXAN Mesna 400mg tablets and 600mg film coated tablet Active ingredient : Mesna Inactive ingredients : calcium hydrogen phosphate, lactos e monohydrate, starch-maize, cellulose microcrystalline, povidone, magnesium stearate. Coating: hypromellose, Macrogol 6000, simethicone, titanium dioxide. Molecular formula : C2H5NaO3S2 with a molecular weight of 164.18. Structural formula : HS-CH2-CH2-SO3Na+

DESCRIPTION

The active ingredient, mesna, is a synthetic sulphydryl compound designated as sodium 2- mercapto-ethane sulphonate. Uromitexan tablets are white oblong, biconvex film-coated tablets, scored on one side and marked “M 4” or “M 6”, containing 400mg or 600mg (respectively) of mesna.

We are one of the leading Exporters of MMR Vaccine that acts as an immunization vaccine against life-threatening diseases like mumps, measles and rubella. Our MMR Vaccine is provided to children around one year and another dose of it is administered at the age of 4-5 years. We provide MMR Vaccine of well-known multinational companies like Merc &Co., GlaxoSmithKline Biologicals, and Sanofi Pasteur with the brand names of M-M-R II, Priorix, and Trimovax respectively. Long-term effects and efficacy are subject to continuing study.

Flu Shot or Influenza Vaccine is an annual vaccine used as a protection against extremely variable influenza virus. Influenza Vaccine that we Export contains one influenza type A subtype H3N2 virus strain, one influenza type A subtype H1N1 (seasonal) virus strain, and one influenza type B virus strain. Our Influenza Vaccine is immensely recommended by the renowned medical practitioners owing to its accurate composition and effective results.

We take immense pleasure in introducing ourselves as one of the leading companies engaged in exporting of Oral Polio Vaccine. Oral Polio Vaccine is a mixture of live attenuated poliovirus strains of three stereotypes, selected by their ability to mimic the immune response following infection with wild polioviruses. Oral Polio Vaccine produces antibodies in the blood of all three types of poliovirus and in the event of infection it protects against polio paralysis by preventing the spread of poliovirus to the nervous system. Oral Polio Vaccine that we provide does not have any side effects.

Decapeptyl (Triptorelin) is prescribed to women who are unable to conceive. It helps to assist pregnancy in certain women who suffer from fertility problems by stimulating the release of pituitary gonadotropins, a hormone related to the hormonal secretions of the ovaries.
Dosage and AdministrationDecapeptyl (Triptorelin) is usually administered as an injection by a physician or other health care professional, and is normally injected into the buttocks. This medication should not be self-injected by patients, as they may not be familiar with the injection procedures or how to dispose of syringes. Patients should always consult their physician before using this medication in order to determine the correct dosage and the frequency at which it should be administered.

Side effectsSide effects which may occur as a result of using Decapeptyl (Triptorelin) include:
Hot flushesMenorrhagiaVaginal drynessMuscle or joint painHair lossIf any of these side effects persist or worsen, you should consult your physician immediately.

Menomune® A/C/Y/W-135, Meningococcal Polysaccharide Vaccine, Groups A, C, Y and W-135  Combined, for subcutaneous use, is a freeze-dried preparation of the group-specific polysaccharide antigens from Neisseria meningitidis, Group A, Group C, Group Y and Group W-135. N meningitidis are cultivated with Mueller Hinton agar 1 and Watson Scherp 2 media. The purified polysaccharide is extracted from the

Neisseria meningitidis cells and separated from the media by procedures which include centrifugation, detergent precipitation, alcohol precipitation, solvent or organic extraction and diafiltration. No preservative is added during manufacture.

The 0.78 mL vial of diluent contains sterile, preservative-free, pyrogen-free distilled water and is used for reconstitution of product supplied in 1 mL vials. The 6 mL vial of diluent contains sterile, pyrogen-free distilled water to which thimerosal (mercury derivative) 1:10, 000 is added as a preservative. The 6 mL vial is for reconstitution of product supplied in 10 mL vials.

After reconstitution with diluent as indicated on the label, the 0.5 mL dose is formulated to contain 50 μg of “isolated product” from each of Groups A, C, Y and W-135 in an isotonic sodium chloride solution. Each dose of vaccine is also formulated to contain 2.5 mg to 5 mg of lactose added as a stabilizer. 3 The vaccine when reconstituted is a clear colorless liquid. Potency is evaluated by measuring the molecular size of each polysaccharide component using a column chromatography method as standardized by the US Food and Drug Administration (FDA) and the World Health Organization (WHO) 4 for Meningococcal Polysaccharide Vaccine. THIS VACCINE CONFORMS TO THE WORLD HEALTH ORGANIZATION (WHO) REQUIREMENTS

CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types 16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant Baculovirus expression vector system in a serum-free culture media composed of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni insect cells, the L1 protein accumulates in the cytoplasm of the cells. The L1 proteins are released by cell disruption and purified by a series of chromatographic and filtration methods. Assembly of the L1 proteins into virus-like particles (VLPs) occurs at the end of the purification process. The purified, non-infectious VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system, AS04, is composed of 3-0-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed on to aluminum (as hydroxide salt).

CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.

CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type 18 L1 protein, 50 mcg of the 3-0-desacyl-4'-monophosphoryl lipid A (MPL), and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain residual amounts of insect cell and viral protein ( < 40 ng) and bacterial cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not contain a preservative.

The tip caps may contain natural rubber latex; the plungers are not made with natural rubber latex.

Owing to our immense expertise, we are now engaged in exporting of Anti Rabies Vaccine. Anti Rabies Vaccine is used to treat the rabies disease which is caused by a viral infection usually spread because of the bite from an infected animal like dogs, bats, foxes, etc. Anti Rabies Vaccine that we provide is prepared from accurate chemical composition and known for providing effective results with minor side-effects. We make available Anti Rabies Vaccine in tamper-proof packaging.

Composition per Single Dose :

• Freeze-dried vaccine : One immunizing dose contains the protective activity of equal to or greater than 2.5 International Units (IU) even after exposure at 37 degree centigrade for one month.
• Rabies Virus (L.Pasteur 2061/Vero) propagated on Vero cell line, inactivated with beta-propiolactone.
• Thiomersol 0.015% added as preservative
• Maltose q.s. per immunizing dose
• Human Serum Albumin q.s. per immunizing dose
• Sodium Chloride (0.9%) for Injection I.P.- 0.5 ml

EUFLEXXA6 is a viscoelastic, sterile solution of highly purified, high molecular weight (2.4-3.6 million daltons) hyaluronan (also known as sodium hyaluronate) in phosphate-buffered saline. EUFLEXXA! is a very highly purified product extracted from bacterial cells. It is a polysaccharide consisting of a repeating is accharide of N-acetylglucosamine and sodium glucuronate, linked by alternating 0, 4, 1, 3 and P-1, 4 glycosidic bonds.

Neulastim® DS 1402051 Data Sheet Neulastim® Pegfilgrastim 6 mg in 0.6 mL (pre-filled syringe), solution for injection Description Therapeutic/Pharmacologic Class of Medicine Haematopoietic growth factor Pharmacotherapeutic group: Cytokines, ATC Code: L03AA13 Type of Dosage Form Solution for injection in a pre-filled syringe. Route of Administration Subcutaneous injection. Sterile/Radioactive Statement Sterile. Qualitative and Quantitative Composition 6 mg of pegfilgrastim in 0.6 mL (10 mg/mL*) solution for injection. * Based on protein only. The concentration is 20 mg/mL if the PEG moiety is included. Pegfilgrastim is composed of filgrastim (recombinant methionyl human G-CSF) with a 20 kDa polyethylene glycol (PEG) molecule covalently bound to the N-terminal methionine residue. Filgrastim is produced by recombinant DNA technology in E coli (K12). Excipients: Sodium acetate**, Sorbitol, Polysorbate 20, Water for injections ** Sodium acetate is formed by titrating glacial acetic acid with sodium hydroxide

Being a highly acclaimed name in the industry engaged in Exporting of quality pharmaceutical products, we offer our clients with TD Vaccine. TD Vaccine is essentially the short form of Tetanus and Diphtheria vaccine and it is used for preventing people from fatal tetanus and diphtheria diseases. TD Vaccine that we export is prepared using superior quality chemicals in accurate composition owing to which it is highly recommended by renowned physicians. Our TD Vaccine is absolutely safe with no side-effects. Mostly used for adults, TD Vaccine is manufactured to protect the user from fatal diseases. Also, we have made available TD Vaccines to the clients at market leading prices.

Nterleukin-2 (aldesleukin, [Proleukin®]) is a cytokine with the following immune - modulating effects: enhancement of lymphocyte mitogenesis and cytotoxicity, induction of lymphocyte - activated (LAK) cells and natural killer (NK) cells, and induction of interferon gamma production. U.S. Food and Drug Administration (FDA) - approved labeled indications include the treatment of metastatic renal cell carcinoma and metastatic malignant melanoma. Other oncologic applications of IL - 2 monotherapy are being actively investigated, principally as a technique to maintain remission or eliminate minimal residual disease in patients with a variety of malignancies, including most prominently leukemias, but also including lymphomas and other solid tumors such as neuroblastoma and breast cancer. IL - 2 has also been used post - autologous bone marrow transplantation as an immunotherapeutic technique to maintain remission and reduce the relapse rate. In HIV-infected patients, there is a reduced endogenous production of IL-2 and a defect in IL-2 receptor expression, respon sible in part for the characteristic reduction in CD4 counts. Exogenous IL-2, in conjunction with antiretroviral therapy, has been investigated as a technique to increase CD4 counts, preserve immune function and hopefully decrease the incidence of opportu nistic infections. It has been proposed that IL-2 in conjunction with combination antiretroviral therapy may be a useful approach for purging HIV from the latently infected CD4 cells. IL-2 has also been investigated as a component of a variety of combinat ion therapies, for example in combination with interferon alpha in the treatment of metastatic renal cell cancer and metastatic melanoma. IL -2 can be administered by subcutaneous injection (low-dose therapy) or into a vein (intermediate or high-dose therapy), either intermittently as a bolus or quick injection, or as a continuous treatment over a defined period of time.

AVONEX is a 166 amino acid glycoprotein with a molecular weight of approximately 22, 500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into which the human interferon beta gene has been introduced. The amino acid sequence of AVONEX is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) International Standard for Interferon, AVONEX has a specific activity of approximately 200 million international units of antiviral activity per mg of interferon beta-1a determined specifically by an in vitro cytopathic effect bioassay using lung carcinoma cells (A549) and Encephalomyocarditis virus (ECM). AVONEX 30 micrograms contains approximately 6 million international units of antiviral activity using this method. The activity against other standards is not known. Comparison of the activity of AVONEX with other interferon betas is not appropriate, because of differences in the reference standards and assays used to measure activity.

Owing to our customer centric beliefs, we are capable of Exporting for our clients safe nf secure Meningitis Vaccine. Meningitis Vaccine is actually used against Neisseria meningitides or Meningococcal bacteria. Meningitis is a dangerous inflammation forms in the lining of the brain and spinal cord. Meningitis Vaccine that we export is highly effective and provides protection against different groups of meningitis such as A, C, Y, etc. Meningitis Vaccine offered by us is widely appreciated by the clients owing to its longer shelf life and high effectiveness. Our Meningitis Vaccine is available in safe tamper-proof packaging.

Symptoms of Meningitis :

• Irritability
• Vomiting
• Drowsiness
• Confusion or altered consciousness
• Headache and neck stiffness associated with fever
• Inability to tolerate light (photophobia) or loud noises (phonophobia)

Hepatitis B Vaccine that we export is used to prevent the human body from hepatitis B virus infection. Hepatitis B virus is responsible for causing life-threatening diseases like liver infection, chronic liver disease, liver cancer, cirrhosis of liver, etc. Hepatitis B Vaccine that we offer is formulated using superior quality ingredients with zero level of synthetic elements. There are some minor side-effects of the Hepatitis B Vaccine like swelling, soreness, redness, etc. Hepatitis B Vaccine offered by us has an outstanding record of safety and effectiveness

FASLODEX® (fulvestrant) injection for intramuscular administration is an estrogen receptor antagonist. The chemical name is 7-alpha-[9-(4, 4, 5, 5, 5-penta fluoropentylsulphinyl) nonyl]estra-1, 3, 5-(10)- triene-3, 17beta-diol. The molecular formula is C32H47F5O3S and its structural formula is:
FASLODEX® (fulvestrant) Structural Formula IllustrationFulvestrant is a white powder with a molecular weight of 606.77. The solution for injection is a clear, colorless to yellow, viscous liquid.
Each injection contains as inactive ingredients: 10% w/v Alcohol, USP, 10% w/v Benzyl Alcohol, NF, and 15% w/v Benzyl Benzoate, USP, as co-solvents, and made up to 100% w/v with Castor Oil, USP as a co-solvent and release rate modifier.

We are the leading Exporter of DPT Vaccine. DPT Vaccine is a combination vaccine used against three most infectious diseases in humans, namely tetanus, diphtheria and pertussis. DPT Vaccine is enriched with diphtheria and tetanus toxoids which is effective in destroying the cells of organism called pertussis. DPT Vaccine offered by us is widely demanded owing to various attributes which include Longer Shelf Life, Accurate chemical composition, high effectiveness and least side effects.

ActHIB ®, Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate), produced by Sanofi Pasteur SA, is a sterile, lyophilized powder which is reconstituted with either saline diluent (0.4% Sodium Chloride) or Tripedia®, Sanofi Pasteur Inc. Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP) (when reconstituted known as TriHIBit®) for intramuscular administration only. The vaccine consists of the Haemophilus b capsular polysaccharide (polyribosyl-ribitol-phosphate, PRP), a high molecular weight polymer prepared from the Haemophilus influenzae type b (Hib) strain 1482 grown in a semi-synthetic medium, covalently bound to tetanus toxoid.1 The lyophilized ActHIB vaccine powder and saline diluent contain no preservative. The tetanus toxoid is prepared by extraction, ammonium sulfate purification, and formalin inactivation of the toxin from cultures of Clostridium tetani (Harvard strain) grown in a modified Mueller and Miller medium.2 The culture medium contains milk derived raw materials (casein derivatives). Further manufacturing process steps reduce residual formaldehyde to levels below 0.5 micrograms (mcg) per dose by calculation. The toxoid is filter sterilized prior to the conjugation process. Potency of ActHIB vaccine is specified on each lot by limits on the content of PRP polysaccharide and protein in each dose and the proportion of polysaccharide and protein in the vaccine which is characterized as high molecular weight conjugate.
When ActHIB is reconstituted with saline diluent (0.4% Sodium Chloride), each 0.5 mL dose is formulated to contain 10 mcg of purified capsular polysaccharide conjugated to 24 mcg of inactivated tetanus toxoid, and 8.5% of sucrose.
When ActHIB is reconstituted with Tripedia vaccine to formulate TriHIBit vaccine, each 0.5 mL dose contains10 mcg of purified capsular polysaccharide conjugated to 24 mcg of inactivated tetanus toxoid, 8.5% of sucrose, 6.7 Lf of diphtheria toxoid, 5 Lf of tetanus toxoid, and 46.8 mcg of pertussis antigens. Tripedia vaccine (vial presentation 0.6 mL) is formulated without preservatives but contains a trace amount of thimerosal [(mercury derivative), ( ≤ 0.3 mcg mercury/dose)] from the manufacturing process. (Refer to product insert for Tripedia vaccine.)

Mencevax ACWY is a lyophilized preparation of purified polysaccharides from Neisseria meningitidis (meningococcus) of groups A, C, W-135 and Y. It is presented as a white pellet in a glass vial together with a separate vial of clear, colourless, sterile saline solvent. When reconstituted with the solvent supplied the vacci ne is ready for subcutaneous injection. Each 0.5 mL dose of reconstituted vaccine contains 50 micrograms of each of the polysaccharide of groups A, C, W-135, and Y.

ENDOXAN Cyclophosphamide powder for injection, 500mg, 1.0g or 2.0g NAME OF DRUG ENDOXAN is available in 3 strengths: 500m g, 1.0g or 2.0g of cyclophosphamide per vial.

DESCRIPTION

Cyclophosphamide is chemically 2-Bis (2-chloroethyl) aminoperhydro-1, 3, 2-oxazaphosphorine 2-oxide. It exists as the monohydrat e. The chemical formula is C7H15Cl2N2O2P.H2O and its molecular weight is 279.1. The CAS number is 6055-19-2 and the chemical structure is as follows: The white crystalline monohydrate is soluble in water (> 4% w/v). Cyclophosphamide monohydrate liquefies when its water of crystallisation is lost.

Ibandronate sodium has the full chemical name of [1-hydroxy-3-(methylpentylamino)propylidene]bis-phosphonic acid, monosodium salt, monohydrate. Its molecular weight is 359. It is a white to off-white powder and is freely soluble in water. BONDRONAT is available as a sterile, clear and colourless concentrated injection for intravenous (IV) infusion containing 6 mg ibandronic acid (as the monosodium salt monohydrate 6.75 mg). The concentrated injection also contains sodium chloride, acetic acid - glacial, sodium acetate and water for injections. BONDRONAT is also available as white to off-white, film-coated tablets containing 50 mg ibandronic acid (as the monosodium salt monohydrate 56.25 mg). The tablets also contain lactose, cellulose microcrystalline, povidone, crospovidone, stearic acid and silica colloidal anhydrous. The tablet film-coating contains hypromellose, titanium dioxide, purified talc and macrogol 6000.

TAXOL (paclitaxel) Injection is a clear, colorless to slightly yellow viscous solution. It is supplied as a nonaqueous solution intended for dilution with a suitable parenteral fluid prior to intravenous infusion. TAXOL is available in 30 mg (5 mL), 100 mg (16.7 mL), and 300 mg (50 mL) multidose vials. Each mL of sterile nonpyrogenic solution contains 6 mg paclitaxel, 527 mg of purified Cremophor® EL (polyoxyethylated castor oil) and 49.7% (v/v) dehydrated alcohol, USP.
Paclitaxel is a natural product with antitumor activity. TAXOL (paclitaxel) is obtained via a semi-synthetic process from Taxus baccata. The chemical name for paclitaxel is 5β, 20-Epoxy-l, 2α, 4, 7β, 10β, 13α-hexahydroxytax-l l-en-9-one 4, 10-diacetate 2-benzoate 13-ester with (2R, 3S)-N-benzoyl-3-phenylisoserine.
Paclitaxel has the following structural formula:
TAXOL® (paclitaxel) INJECTION Structural Formula Illustration
Paclitaxel is a white to off-white crystalline powder with the empirical formula C47H51NO14 and a molecular weight of 853.9. It is highly lipophilic, insoluble in water, and melts at around 216-217° C.

HAVpur - Pharmacology: Provides active immunization against hepatitis A.
Indication: Active immunization of patients 12 mo of age and older against disease caused by hepatitis A virus.
VAQTA is indicated for active pre-exposure prophylaxis against disease caused by hepatitis A virus in persons 2 years of age and older. Primary immunization should be given at least 2 weeks prior to expected exposure to HAV.
Individuals who are or will be at increased risk of infection by HAV include:
TRAVELERS
Persons traveling to areas of higher endemicity for hepatitis A. These areas include, but are not limited to, Africa, Asia (except Japan), the Mediterranean basin, Eastern Europe, the Middle East, Central and South America, Mexico, and parts of the Caribbean. Current CDC (Centers for Disease Control and Prevention) advisories should be consulted with regard to specific locales.
MILITARY PERSONNEL
PEOPLE LIVING, IN, OR RELOCATING TO, AREAS OF HIGH ENDEMICITY
CERTAIN ETHNIC AND GEOGRAPHIC POPULATIONS THAT EXPERIENCE CYCLIC HEPATITIS A EPIDEMICS SUCH AS:
Native peoples of Alaska and the Americas.
OTHERS
Persons engaging in high-risk sexual activity (such as homosexually active males); users of illicit injectable drugs; residents of a community experiencing an outbreak of hepatitis A.
Hemophiliacs and other recipients of therapeutic blood products (see and ).
Persons who test positive for hepatitis C virus and have diagnosed liver disease.
Although the epidemiology of hepatitis A does not permit the identification of other specific populations at high risk of disease, outbreaks of hepatitis A or exposure to hepatitis A virus have been described in a variety of populations in which VAQTA may be useful:
    Certain institutional workers (e.g., caretakers for the developmentally challenged)    Employees of child day-care centers    Laboratory workers who handle live hepatitis A virus    Handlers of primate animals that may be harboring HAV

PEOPLE EXPOSED TO HEPATITIS A
For those requiring both immediate and long-term protection, VAQTA may be administered concomitantly with IG.
Revaccination
See, .
Use With Other Vaccines
VAQTA may be given concomitantly at separate injection sites with typhoid and yellow fever vaccines. The GMTs for hepatitis A when VAQTA, typhoid and yellow fever vaccines were administered concomitantly were reduced when compared to VAQTA alone. Following receipt of the booster dose of VAQTA, the GMTs for hepatitis A in these two groups were observed to be comparable. (See, and, .)
The Advisory Committee on Immunization Practices has stated that limited data from studies conducted among adults indicate that simultaneous administration of hepatitis A vaccine with diphtheria, poliovirus (oral and inactivated), tetanus, oral typhoid, cholera, Japanese encephalitis, rabies, or yellow fever vaccine does not decrease the immune response to either vaccine or increase the frequency of reported adverse events. Studies indicate that hepatitis B vaccine can be administered with VAQTA without affecting immunogenicity or increasing the frequency of adverse events.
Use With Immune Globulin
For individuals requiring either post-exposure prophylaxis or combined immediate and longer-term protection (e.g., travelers departing on short notice to endemic areas), VAQTA may be administered concomitantly with IG using separate sites and syringes (see and ).
VAQTA IS NOT RECOMMENDED FOR USE IN INFANTS YOUNGER THAN 2 YEARS OF AGE SINCE DATA ON USE IN THIS AGE GROUP ARE NOT CURRENTLY AVAILABLE.
Read more: http://www.ndrugs.com/?s=havpur#ixzz3LHQeO0yX

FLUARIX, Influenza Vaccine, for intramuscular injection, is a sterile colorless and slightly opalescent suspension. FLUARIX is a vaccine prepared from influenza viruses propagated in embryonated chicken eggs. Each of the influenza viruses is produced and purified separately. After harvesting the virus-containing fluids, each influenza virus is concentrated and purified by zonal centrifugation using a linear sucrose density gradient solution containing detergent to disrupt the viruses. Following dilution, the vaccine is further purified by diafiltration. Each influenza virus solution is inactivated by the consecutive effects of sodium deoxycholate and formaldehyde leading to the production of a “split virus.” Each split inactivated virus is then suspended in sodium phosphate-buffered isotonic sodium chloride solution. The vaccine is formulated from the 3 split inactivated virus solutions.
FLUARIX has been standardized according to USPHS requirements for the 2014-2015 influenza season and is formulated to contain 45 micrograms (mcg) hemagglutinin (HA) per 0.5-mL dose, in the recommended ratio of 15 mcg HA of each of the following 3 strains: A/Christchurch/16/2010 NIB-74XP (H1N1) (an A/California/7/2009-like virus), A/Texas/50/2012 NYMC X-223A (H3N2), and B/Massachusetts/2/2012 NYMC BX-51B.
FLUARIX is formulated without preservatives. FLUARIX does not contain thimerosal. Each 0.5-mL dose also contains octoxynol-10 (TRITON® X-100) ≤ 0.085 mg, a-tocopheryl hydrogen succinate ≤ 0.1 mg, and polysorbate 80 (Tween 80) ≤ 0.415 mg. Each dose may also contain residual amounts of hydrocortisone ≤ 0.0016 mcg, gentamicin sulfate ≤ 0.15 mcg, ovalbumin ≤ 0.05 mcg, formaldehyde ≤ 5 mcg, and sodium deoxycholate ≤ 50 mcg from the manufacturing process.
The tip caps and plungers of the prefilled syringes of FLUARIX are not made with natural rubber latex.

Gemini DescriptionGemini-born are quick witted and always on their toes. Gemini is represented by the symbol of Twins. Gemini-born are charming and friendly individuals, who like to indulge in talking, and they talk quite a lot. It is the very curiosity and cleverness that makes them such a hit at the parties and social gatherings. But, the Gemini are not merely good talkers, they also love to listen, to learn and to react. Their life, in total, revolves around their need to communicate. The conversations that Gemini indulge in are not always just idle chats. Most Gemini need an incoming flow of information to feed their intellectual inclinations. In fact, they may probe endlessly for more facts and details, as for them the more information they process, the better it is. Relationships too are very important to the Gemini, and that is why you would always find the Gemini taking time out from their busy schedules to meet people from the different walks of life, and learn from their experiences – these experiences better equip them to nurture their relationship with their friends and family members positively. Handle your relationships even better with the help of the totally personalised Birth Chart based service Relationships Ask 3 Question Detailed OR Saas Bahu Compatibility Reading.
Gemini-born are rational and practical by nature, and at the same time they are also imaginative and creative beings. However, Gemini-born face a major problem and that is about their double thinking nature. Most of the times, it’s not sure which Twin might show up and this certainly makes them seem restless and erratic. At times, they can be quite moody and act on simple impulse. It is this liberal energy, which can also regard them as flyaway and unfocused, behind all that restlessness. While their expansiveness may be misinterpreted as shrewd by some, the Gemini generally have their hearts in the right place. To gain a deeper insight into your future prospects, try the Birth Chart based servic

Avastin (bevacizumab) is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF) in in vitro and in vivo assay systems. Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Avastin has an approximate molecular weight of 149 kD. Bevacizumab is produced in a mammalian cell (Chinese Hamster Ovary) expression system in a nutrient medium containing the antibiotic gentamicin. Gentamicin is not detectable in the final product.
Avastin is a clear to slightly opalescent, colorless to pale brown, sterile, pH 6.2 solution for intravenous infusion. Avastin is supplied in 100 mg and 400 mg preservative-free, single-use vials to deliver 4 mL or 16 mL of Avastin (25 mg/mL). The 100 mg product is formulated in 240 mg a, a-trehalose dihydrate, 23.2 mg sodium phosphate (monobasic, monohydrate), 4.8 mg sodium phosphate (dibasic, anhydrous), 1.6 mg polysorbate 20, and Water for Injection, USP. The 400 mg product is formulated in 960 mg a, a-trehalose dihydrate, 92.8 mg sodium phosphate (monobasic, monohydrate), 19.2 mg sodium phosphate (dibasic, anhydrous), 6.4 mg polysorbate 20, and Water for Injection, USP.

Our range of Biomab EGFR - Nimotuzumab 50mg Injection are known for their effectiveness and do not have any side effect. We manufacture our products from certified and well-tested ingredients. Our Biomab EGFR - Nimotuzumab 50mg Injection are delivered with zero defect at the desired destination within stipulated time frame. We offer our Biomab EGFR - Nimotuzumab 50mg Injection at industry leading rates. BIOMAb EGFR, a humanized monoclonal antibody falls under a class of cancer treatment option known as targeted therapy.

Rhogam Injection

We hold expertise in providing a wide range of Wepox 4000 IU Injection (Rhu-erythropoietin). These are prepared in hygienic environment and with proper measure in formulating them. Our entire product range is treasured among them for its long shelf life and effective results.

PRIMACOR™ 3003 Copolymer is an ethylene acrylic acid copolymer which has been specifically designed by Dow for use as an adhesive or sealant layer in extrusion coating and extrusion lamination.

PRIMACOR 3003 Copolymer exhibits :

• Excellent draw-down and edge stability
• Excellent organoleptic properties
• Excellent toughness and strength
• Outstanding environmental stress crack and product resistance
• Excellent hot-tack and sealability
• Adhesion to paper, paperboard, metals and polyethylenes
• Insensitivity to moisture

ENGERIX-B [Hepatitis B Vaccine (Recombinant)] is a sterile suspension of noninfectious hepatitis B virus surface antigen (HBsAg) for intramuscular administration. It contains purified surface antigen of the virus obtained by culturing genetically engineered Saccharomyces cerevisiae cells, which carry the surface antigen gene of the hepatitis B virus. The HBsAg expressed in the cells is purified by several physicochemical steps and formulated as a suspension of the antigen adsorbed on aluminum hydroxide. The procedures used to manufacture ENGERIX-B result in a product that contains no more than 5% yeast protein.
Each 0.5-mL pediatric/adolescent dose contains 10 mcg of HBsAg adsorbed on 0.25 mg aluminum as aluminum hydroxide.
Each 1-mL adult dose contains 20 mcg of HBsAg adsorbed on 0.5 mg aluminum as aluminum hydroxide.
ENGERIX-B contains the following excipients: Sodium chloride (9 mg/mL) and phosphate buffers (disodium phosphate dihydrate, 0.98 mg/mL; sodium dihydrogen phosphate dihydrate, 0.71 mg/mL).
ENGERIX-B is available in vials and prefilled syringes. The tip caps of the prefilled syringes may contain natural rubber latex; the plungers are not made with natural rubber latex. The vial stoppers are not made with natural rubber latex.
ENGERIX-B is formulated without preservatives.

HAVRIX (Hepatitis A Vaccine) is a sterile suspension of inactivated virus for intramuscul ar administration. The virus (strain HM1 75) is propagated in MRC-5 human diploid cells. After removal of the cell culture medium, the cells are lysed to form a suspension. This suspension is purified through ultrafiltration and gel permeation chromatography procedures. Treatment of this lysate with formalin ensures viral inactivation. Viral antigen activity is referenced to a standard using an enzyme linke d immunosorbent assay (ELISA), and is therefore expressed in terms of ELISA Units (EL.U.). Each 1 - mL adult dose of vaccine contains 1440 EL.U. of viral antigen, adsorbed on 0.5 mg of aluminum as aluminum hydroxide.

We are providing wide assortment of antibacterial products like life saving drugs, antibacterial antibiotics, life saving generic drugs, generic antibiotic drugs to our international as well as domestic clients. It is effective against various ailments, which are due to the growth of harmful bacteria inside the body. It destroys bacterial and retard its multiplication in the body. The efficiency of the antibiotics depends upon its ability to reach the infection spot and the site of infection.

Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1 NEUPOGEN® is produced by Escherichia coli (E coli) bacteria into which has been inserted the human granulocyte colony-stimulating factor gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis‚ except for the addition of an N-terminal methionine necessary for expression in E coli. Because NEUPOGEN® is produced in E coli‚ the product is nonglycosylated and thus differs from G-CSF isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for parenteral administration containing Filgrastim at a specific activity of 1.0 ± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay). The product is available in single use vials and prefilled syringes. The single use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0 mL or 1.6 mL, respectively. The single use prefilled syringes contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively. See table below for product composition of each single use vial or prefilled syringe.
   300 mcg/ 1.0 mL Vial  480 mcg/ 1.6 mL Vial  300 mcg/ 0.5 mL Syringe  480 mcg/ 0.8 mL SyringeFilgrastim  300 mcg  480 mcg  300 mcg  480 mcgAcetate  0.59 mg  0.94 mg  0.295 mg  0.472 mgSorbitol  50.0 mg  80.0 mg  25.0 mg  40.0 mgPolysorbate 80  0.04 mg  0.064 mg  0.02 mg  0.032 mgSodium  0.035 mg  0.056 mg  0.0175 mg  0.028 mgWater for Injection USP q.s. ad  1.0 mL  1.6 mL  0.5 mL  0.8 mL
REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte colonystimulating factor: Molecular and biological characterization. Immunobiol. 1986;172:175-184.

(50/250, 50/100, 50/500)
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Seretide Accuhaler- 50/500 (Fluticasone/Salmeterol)

Erythropoietin (EPO) is a glycoprotein hormone produced primarily by the kidney in response to hypoxia and is the key regulator of red blood cell (RBC) production. EPO is involved in all phases of erythroid development, and has its principal effect at the level of erythroid precursors. After EPO binds to its cell surface receptor, it activates signal transduction pathways that interfere with apoptosis and stimulates erythoid cell proliferation.

Erythropoietin stimulates erythropoiesis in anaemic patients with chronic renal failure in whom the endogenous production of erythropoietin is impaired. Because of the length of time required for erythropoiesis – several days for erythroid progenitors to mature and be released into the circulation – a clinically significant increase in haemoglobin is usually not observed in less than two weeks and may require up to ten weeks in some patients.

Erythropoiesis-stimulating agents ESAs are growth factors that primarily stimulate red cell production. Erythropoietin receptors may be expressed on the surface of a variety of tumour cells (see PRECAUTIONS – Use in Cancer Patients).

We are a prominent name in the industry engaged in exporting of Chicken Pox Vaccine. Chicken Pox Vaccine is used for the treatment of the very common disease, i.e., chicken pox. Chicken Pox Vaccine that we export is highly recommended for children as they have the most favorable chances to catch the disease. Our Chicken Pox Vaccine is prepared using the finest quality chemicals and is free from any sort of serious side-effects.

Chicken Pox Vaccine Is Recommended For :

• All children of age less than age 13 years (one dose at 12–15 months and a second dose at age 4–6 years)
• Everyone age 13 years and older who has never had chickenpox (two doses, given 4–8 weeks apart)
• Almost all (97%) children between age 12 months and 12 years develop immunity to the disease after one dose of vaccine. For older children and adults, an average of 78% develops immunity after one dose and 99% develop immunity after the recommended two doses.

 Haemophilus B is a type of influenza (flu) caused by bacteria. Haemophilus B bacteria can cause breathing problems or meningitis, and these infections can be fatal. Haemophilus B conjugate (PRP-T) vaccine is used to prevent this disease in children, and is sometimes combined with vaccines to protect against other diseases. This vaccine is given to children between the ages of 2 months and 18 months old. The vaccine works by exposing your child to a small amount of the bacteria or a protein from the bacteria, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body, and will not protect against other types of influenza. Haemophilus B conjugate vaccine is not for use in children younger than 6 weeks. When used in combination with certain diphtheria vaccines, this vaccine may not be used in children younger than 15 months. Like any vaccine, haemophilus B conjugate vaccine may not provide protection from disease in every person.
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cAELYX, a pegylated liposomal formulation of doxorubicin hydrochloride, contains doxorubicin encapsulated in liposomes having surface-bound methoxypolyethylene glycol groups (pegylated liposomes). This process is known as pegylation and protects the liposomes from detection by the mononuclear phagocyte system (MPS), which increases blood circulation time. The chemical structure of doxorubicin hydrochloride (CAS-25316-40-9) is: CAELYX is a concentrate for infusion presented as a sterile, translucent, red suspension in glass vials containing 10 mL or 25 mL for single-use intravenous infusion. Each vial contains 20 mg or 50 mg doxorubicin hydrochloride (HCl) at a concentration of 2.0 mg/mL in a pegylated liposomal formulation. The pH of the suspension is 6.5. 

CAELYX, a pegylated liposomal formulation of doxorubicin hydrochloride, contains doxorubicin encapsulated in liposomes having surface-bound methoxypolyethylene glycol groups (pegylated liposomes). This process is known as pegylation and protects the liposomes from detection by the mononuclear phagocyte system (MPS), which increases blood circulation time. The chemical structure of doxorubicin hydrochloride (CAS-25316-40-9) is: CAELYX is a concentrate for infusion presented as a sterile, translucent, red suspension in glass vials containing 10 mL or 25 mL for single-use intravenous infusion. Each vial contains 20 mg or 50 mg doxorubicin hydrochloride (HCl) at a concentration of 2.0 mg/mL in a pegylated liposomal formulation. The pH of the suspension is 6.5. 

Cladribine Injection (also commonly known as 2-chloro-2Î-deoxy- β -D-adenosine) is a synthetic antineoplastic agent for continuous intravenous infusion. It is a clear, colorless, sterile, preservative-free, isotonic solution. Cladribine Injection is available in single-use vials containing 10 mg (1 mg/mL) of Cladribine, a chlorinated purine nucleoside analog. Each milliliter of Cladribine Injection contains 1 mg of the active ingredient and 9 mg (0.15 mEq) of sodium chloride as an inactive ingredient. The solution has a pH range of 5.5 to 8.0. Phosphoric acid and/or dibasic sodium phosphate may have been added to adjust the pH to 6.3±0.3.

Daunoblastin - Daunoblastin is an antineoplastic in the anthracycline classDoxorubicin is widely used for the treatment of several solid tumors while Daunoblastin and idarubicin are used exclusively for the treatment of leukemia. Daunoblastin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Daunoblastin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.

ERWINAZE (asparaginase Erwinia chrysanthemi) contains an asparagine specific enzyme derived from Erwinia chrysanthemi. L-asparaginase is a tetrameric enzyme consisting of four identical subunits, each having a molecular weight of about 35 kDa. The activity of ERWINAZE is expressed in terms of International Units.
ERWINAZE is supplied as a sterile, lyophilized, white powder in vials. Each vial contains 10, 000 International Units of asparaginase Erwinia chrysanthemi, and the following inactive ingredients: glucose monohydrate (5.0 mg), sodium chloride (0.5 mg).

FLUDARA FOR INJECTION contains fludara (fludarabine) bine phosphate, a fluorinated nucleotide analog of the antiviral agent vidarabine, 9-p-D-arabinofuranosyladenine (ara-A) that is relatively resistant to deamination by adenosine deaminase. Each vial of sterile lyophilized solid cake contains 50 mg of the active ingredient fludara (fludarabine) bine phosphate, 50 mg of mannitol, and sodium hydroxide to adjust pH to 7.7. The pH range for the final product is 7.2-8.2. Reconstitution with 2 mL of Sterile Water for Injection, USP, results in a solution containing 25 mg/mL of fludara (fludarabine) bine phosphate intended for intravenous administration.
The chemical name for fludara (fludarabine) bine phosphate is 9H-Purin-6-amine, 2-fluoro-9-(5-0-phosphono- 0-D-arabino-furanosyl) (2-fluoro-ara-AMP). The molecular formula of fludara (fludarabine) bine phosphate is C10H13FN5O7P (MW 365.2) and the structure is:
Fludara® (fludara (fludarabine) bine phosphate) Structural Formula Illustration