Cartel International

Ankleshwar Gidc, Ankleshwar, Gujarat

• MOQ 5 Kilogram

N-Hydroxysuccinimide (NHS) is an organic compound with the molecular formula  C4H5NO3 C 4 ​ H 5 ​ NO 3 ​  and a CAS number of 6066-82-6. It appears as a white solid and is primarily used as a reagent in organic chemistry, particularly for preparing active esters in peptide synthesis and bioconjugation techniques. Chemical Properties Molecular Weight : 115.09 g/mol Melting Point : 93 - 100 °C 4 . Solubility : Soluble in water 2 . Synthesis NHS can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride. This process yields NHS, which can then be utilized to activate carboxylic acids, facilitating their reaction with amines to form amides, a crucial step in peptide synthesis 5 . Applications NHS is widely employed in various applications: Peptide Synthesis : It is used to create NHS esters from carboxylic acids, which are then used to couple with amines to form peptides 3 . Protein Modification : NHS esters are commonly used for labeling proteins with fluorescent dyes or enzymes, enhancing their utility in biochemical assays 5 . Biosensor Development : NHS can be combined with coupling reagents like EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide) for enzyme immobilization in biosensors 3 . Alternatives There are several alternatives to NHS for similar applications: Sulfo-NHS : A water-soluble analog. Hydroxybenzotriazole (HOBt)  and  1-Hydroxy-7-azabenzotriazole (HOAt) : Other reagents used for activating carboxylic acids 2

• CAS No.7681-65-4
• EINECS No.231-674-6
• Purity99.98
• ApplicationPharma
• TypeInorganic Compound
• Warranty5 Years
• MaterialCopper(I) iodide (CuI)
• Size25 Kg Drum
• Other NamesCuprous Iodide
• Country of OriginIndia
• ColorWhite