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benoquin cream is used for depigmentation of the skin as a treatment for widespread vitiligo, a skin condition in which irregular patches of skin, covering about 50% of the body surface, lose colour and become whitened. This is caused by destruction of the pigment producing cells called melanocytes. Benoquin cream is used as a skin lightener in people with vitiligo, to reduce the colour of patches of skin that contain pigment so that they match the areas of skin that have lost colour. Decolouration of the skin using benoquin cream is permanent and makes the skin sensitive to sunburn.