Adam Fabriwerk Pvt. Ltd.

Kandivali East, Mumbai, Maharashtra

Ointment mixer Designed for the Process With long experience at the leading edge of vacuum processing, Adam Fabriwerk has developed a system which addresses the fundamental requirements of the served markets, including. The principal applications for the system are in the pharmaceutical and premium cosmetics sectors.

Our mobile skids are engineered, designed for efficient mixing and blending operations and can be moved around from one area to another. They can be custom optimized to suit your specific requirement of mixing and blending. They are compact, skid mounted and portable. They are cost-effective and ideal for mixing and blending of aseptic liquids of smaller capacities.

ADVANTAGES

• Fast and easy installation
• Portable and compact
• Heating / Cooling options
• SIP / CIP / DIP options
• Full / Semi automated operation
• Capacities : 5 to 500 Litres

KEY FEATURES

• Bottom mounted magnetic mixers with options for low / medium / high shear applications
• Flush bottom outlet valve with sampling / sterilization configurations
• Sterile flange connections of top dish / side ports to enhance CIP / SIP operations
• pH, temperature, conductivity, DO sensing through sanitary port on the vessel shell
• Load cell for weight measurement / Level sensors for level measurements
• 21 CFR part 11 compliant automated system

Our integrated skids are a fully integrated end to end solutions, seamlessly integrating to cater to your aseptic process fluid handling applications. They are ideal for handling medium to high capacities. They can be customized and optimized to suit your requirements. The systems design ensures 100% cleanability.

DESIGN, ENGINEERING, AUTOMATION

The systems are designed and engineered at our design center with experienced and highly qualified design team. The systems are built in the latest simulation and CAD soware and visualized in 3D before being approved for manufacturing. All the equipments are fully integrated to perform as a single system with high quality and reliable automation. They are programmed in accordance with S88 and automated in accordance with GAMP 5 standards and are 21 CFR part 11 compliant.

TESTING & FACTORY ACCEPTANCE TEST (FAT)

All systems are tested at our dedicated FAT testing area that are fully equipped with all required utilities. High quality testing instruments ensure the systems work fine under the designed conditions. Our QA team ensures complete documentation that are required before and during the FAT.

KEY FEATURES

• Designed as per US FDA / cGMP / ASME/ PED/ compliance with ASME - BPE norms
• 21 CFR part 11 compliant, fully automated PLC controlled touch screen HMI
• Bottom mounted magnetic mixers with options for low / medium / high shear applications
• Flush bottom outlet valve with sampling / sterilization configurations
• Sterile flange connections of top dish / side ports to enhance CIP / SIP operations
• pH, temperature, conductivity, DO sensing through sanitary port on vessel shell
• Load cell for weight measurement / Level sensors for level measurements
• Block valves for dead leg compliance and compactness
• Components and instruments from reputed international vendors
• Interconnected product piping through sampling systems and pumps with filtration skids

We have been a leader for over 35 years with considerable expertise in designing and engineering systems for the manufacture of Ointment and Creams. Our systems are fully optimized for delivering the best performance with reduced life-cycle cost. Our systems are designed for optimization of key resources and designed with features that include;

• Flexible process parameters setting
• Variable shear force adjustment
• Fully contained processing system

• The easy-to-use mixer control package can incorporate process parameters storage for simple and fast set-up
• Heating / cooling and insulated jackets with temperature control and safety equipment
• Semi Contra Rotary agitator with open slot scraper design
• Short loop product re-circulation for smaller batch sizes
• Hydraulic lifting on manufacturing vessel top dish to facilitate product recovery
• Separate pre-mix vessels for wax and water phase
• Process piping with transfer panel design for automated plants
• Cleaning-in-place cycles with dosing systems
• In-line high shear mixer options

VESSEL DESIGN

• Extensive research & development has produced the best combination of vessel and agitation system, offering high productivity, quality and yield
• Low relative batch size
• Conical design and proven geometric ratios ensure optimum product flow
• All surfaces angled to ensure ease of cleaning during CIP operations

INTEGRATED VACUUM SYSTEMS

• Fully controllable to permit variation of vacuum levels according to the process phase
• Vacuum line can be fully flushed for sanitation purposes

USER FRIENDLY INTERFACE

• The easy-to-use mixer control package can incorporate process parameters storage for simple and fast set-up
• PLC based, with touch screen MMI and SCADA packages
• Choice of packages to suit application requirements
• Flexible configuration

We provide customized, end to end solutions for liquid oral plants that are fully automated with SCADA controls or semi-automated as required. Our plants are designed with the highest quality of fabrication standards using the best components and instruments. They are also fully optimized for delivering the best performance with reduced life-cycle cost.

PROCESS EQUIPMENTS

• Material handling and transfer
• Sugar syrup preparation
• Sugar syrup pre-filtration
• Solution preparation
• Solution storage
• Platform structure
• Transfer panels
• CIP Systems
• Plant automation
• API mixing

STORAGE SYSTEMS

• Raw material storage
• Inverted sugar storage
• Liquid glucose storage
• Glycerine storage

KEY FEATURES, OUR PRODUCTS AND SERVICES

• Design of process, equipments and transfer piping
• Transfer systems for sugar through vacuum system
• Sugar preparation system with jacketed, insulated and cladded vessel with bottom entry propeller mixer for vigorous mixing
• In-line high shear mixer for suspensions
• Process vessels rated for vacuum
• EHEDG / 3A approved twin lobe pumps
• Electrically heat traced, insulated transfer lines of liquid glucose
• Back-washable stainless steel sintered filter for filtration
• Sanitary piping systems with butterfly valves
• Stainless steel operating platform with staircase and railing
• 21 CFR Part 11 compliant PLC / SCADA based automation system
• Automated CIP system
• Highly experienced team for installation and validation support

Flush Bottom Outlet value (Zero Dead Leg), Bottom mounted Magnetic mixer with speed variation from 50 to 350 RPM, Sterile Flange Connections for Top dish nozzles to enhance CIP, SIP operations, Temperature sensing through sanitary knuckle port on vessel shell, Conductivity sensing through sanitary knuckle port on vessel shell, Vessels are designed in accordance with ASME BPE Guidelines

Oral processing plant The principal applications for the system are in the pharmaceutical and premium cosmetics sectors. Heating cooling and insulated jackets complete with temperature control and safety equipment, Semi Contra Rotary agitator with open slot scraper design, Hydraulic lifting on manufacturing vessel top dish to facilitate product recovery,