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Our Products
Our product range contains a wide range of Abraxane Vial Injection, Sevoflurane 250 ml, VECURONIUM BROMIDE INJECTION 4 MG /10MG, Gemzar 200ml Injection and Bortezomib Injection
Abraxane is classified as a “plant alkaloid, ” a “taxane” and an “antimicrotubule agent. Abraxane for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension). It is indicated for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. And, prior therapy should have included an anthracycline unless clinically contraindicated. We are engrossed as Abraxane Vial Injection Exporter and Supplier from Maharashtra (India). Customers can avail Abraxane Vial Injection from us affordable prices.
Side Effects :
The following side effects are common (occurring in greater than 30%) for patients taking Abraxane: However these side effects are quite manageable and there are many options to minimize or prevent them.
Sevoflurane 250 ml is indicated for induction and maintenance of general anaesthesia in adult and pediatric patients for inpatient and outpatient surgery.Sevoflurane should be administered only by persons trained in the administration of general anesthesia. Facilities for maintenance of a patentairway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. Since level of anesthesia may be altered rapidly, only vaporizers producing predictable concentrations of sevoflurane should be used.
There are many generic manufacturers in India who manufacture Sevoflurane 250 ml including Baxter india Pvt Ltd etc.
3s corporation is Supplier, Exporter , Wholesaler for Sevoflurane 250 ml in India.
ADDITIONAL INFORMATION
Surgical levels of anesthesia can usually be achieved with concentrations of 0.5 – 3% sevoflurane with or without the concomitant use of nitrous oxide. Sevoflurane can be administered with any type of anesthesia circuit.
SIDE EFFECTS CARDIOVASCULAR
Bradycardia 5%, Hypotention 4%, Tachycardia 2%
NERVOUS SYSTEMAgitation 7%
RESPIRATORY SYSTEMLaryngospasm 8%, Airway obstruction 8%, Breathholding 5%, Cough Increased 5%
CARDIOVASCULARTachycardia 6%, Hypotension 4%
NERVOUS SYSTEMAgitation 15%
RESPIRATORY SYSTEMBreathholding 5%, Cough Increased 5%, Laryngospasm 3%, Apnea 2%
DIGESTIVE SYSTEM
Increased salivation 2%
Vecuronium bromide Injection 4 mg /10mg is a nondepolarizing neuromuscular blocking agent of intermediate duration, Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
There are many generic manufacturers in India who manufactureVecuronium bromide Injection 4 mg /10mg including Sun Pharmaceutical Industries Ltd etc.
3s corporation is Supplier, Exporter , Wholesaler for Vecuronium bromide Injection 4 mg /10mg in India
ADDITIONAL INFORMATION
Clinicians must use extreme caution to prevent dosing errors when switching between the various vial sizes
SIDE EFFECTS
The most frequent side effect to nondepolarizing blocking agents as a class consists of an extension of the drug’s pharmacological action beyond the time period needed. This may vary from skeletal muscle weakness to profound and prolonged skeletal muscle paralysis resulting in respiration insufficiency or apnea.
Inadequate reversal of the neuromuscular blockade is possible with vecuronium bromide as with all curariform drugs. These side effects are managed by manual or mechanical ventilation until recovery is judged adequate. Little or no increase in intensity of blockade or duration of action with vecuronium bromide is noted from the use of thiobarbiturates, narcotic analgesics, nitrous oxide, or droperidol.
The administration of vecuronium bromide has been associated with rare instances of hypersensitivity reactions (bronchospasm, hypotension and/or tachycardia, sometimes associated with acute urticaria or erythema).
Gemzar is a nucleoside analog used as chemotherapy. It is used in various carcinomas i.e. Non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It is marketed as Gemzar by Eli Lilly and Company. We are a trusted Exporter and Supplier of Gemzar Injection from Maharashtra (India). We are capable of delivering bulk quantities of Gemzar Injection in a short period of time. Customers can avail them from us at affordable prices.
Detailed Description : Gemzar is a nucleoside analog used as chemotherapy. It is marketed as Gemzar® by Eli Lilly and Company. As with fluorouracil and other analogues of pyrimidines, the drug replaces one of the building blocks of nucleic acids, in this case cytidine, during DNA replication. The process arrests tumor growth, as new nucleosides cannot be attached to the “faulty” nucleoside, resulting in apoptosis (cellular “suicide”). Gemzar is used in various carcinomas: non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It is being investigated for use in oesophageal cancer, and is used experimentally in lymphomas and various other tumor types.
Pharmacology : Gemzar is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine – which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the “S” phase (or DNA synthesis phase of the cell cycle), stopping normal development and division. Gemzar blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Gemzar blocks the incorporation of the thymidine nucleotide into the DNA strand
Alimta is used to treat certain types of cancer such as lung cancer, mesothelioma and many more. It is a trade name for ‘Pemetrexed’ and manufactured by Eli Lilly. Alimta 500 mg Injection Suspension is a chemotherapy drug that is used alone or in combination with other medications to slow or stop cancer cell growth. It is a cancer medication that interferes with the growth of cancer. We are a well-known Alimta 500 Mg Injection Suspension Exporter and Supplier from Maharashtra (India). We can process bulk orders of our product as per the customer’s requirements.
Details
Bortezomib for Injection is an antineoplastic agent available for intravenous injection or subcutaneous use. It is used in the treatment of Multiple Myeloma and Mantle Cell Lymphoma . Each vial contains bortezomib as a sterile lyophilized powder and inactive ingredient.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine. It comes in two dosage i.e. 2 mg & 3.5 mg. It has to be stored at 2-8 degree celsius and comes in powder form with solvent.
It is manufactured by many Indian manufacturers like Jannsen, Celon Labs, Natco Pharma etc. 3s corporation is supplier, Exporter for Bortezomib for Injection in India. It is popularly known as Velcade in Europe and America.
ADDITIONAL INFORMATION
SIDE EFFECTS
Apart from being one of the most preferred medications for the treatment of myeloma, Liposomal Doxorubicin is classified as an anthracycline antibiotic, a chemotherapy drug, typically given to treat advanced ovarian cancer, advanced breast cancer and AIDS-related Kaposi's sarcoma. We are a renowned Liposomal Doxorubicin Injection Exporter and Supplier from Maharashtra (India). Our Liposomal Doxorubicin Injection is individually manufactured under our vendor’s sterile and advanced facility. Customers can avail them from us in bulk quantities and at reasonable prices.
Faslodex 250 mg Injection is used for the treatment of hormone receptor-positive metastatic breast cancer found in postmenopausal women. We are counted among the top Suppliers and Exporters of Faslodex 250 Mg Injection from Maharashtra, India. It fights cancer as an estrogen receptor down-regulator. It is manufactured by AstraZeneca Pharmaceuticals. The Faslodex 250 Mg Injection that we offer is well-tested and therefore, is safe to use.
Other Information :
Bendamustine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white blood cells). Bendamustine injection is also used to treat a type of non-Hodgkins lymphoma (NHL: cancer that begins in a type of white blood cell that normally fights infection) that is slow spreading, but has continued to worsen during or after treatment with another medication. Bendamustine is in a class of medications called alkylating agents. It works by killing existing cancer cells and limiting the growth of new cancer cells.
ADDITIONAL INFORMATION
When bendamustine injection is used to treat CLL, it is usually injected once a day for 2 days, followed by 26 days when the medication is not given. This treatment period is called a cycle, and the cycle may be repeated every 28 days for as long as 6 cycles. When bendamustine injection is used to treat NHL, it is usually injected once a day for 2 days, followed by 19 days when the medication is not given. This treatment cycle may be repeated every 21 days for up to 8 cycles.
SIDE EFFECTS BENDAMUSTINE INJECTION MAY CAUSE SIDE EFFECTS. TELL YOUR DOCTOR IF ANY OF THESE SYMPTOMS ARE SEVERE OR DO NOT GO AWAY:
Bendamustine injection may cause infertility in some men. This infertility may end after treatment, may last for several years, or may be permanent. Talk to your doctor about the risks of receiving this medication.
Irinotecan is used alone or in combination with other medications to treat colon or rectal cancer (cancer that begins in the large intestine). Irinotecan is in a class of antineoplastic medications called topoisomerase I inhibitors. It works by stopping the growth of cancer cells.
SIDE EFFECTS
nauseavomiting, constipation, swelling and sores in the mouth , heartburn, loss of appetite, weight loss , hair loss , weakness , sleepiness pain, especially back pain , chest pain, yellowing of the skin or eyes, swollen stomach , unexpected or unusual weight gain, swelling of the arms, hands, feet, ankles, or lower legs , difficulty breathing or swallowing.
Ondansetron Injection USP 8 mg belongs to the class of medications called 5-HT3 receptor antagonists. This medication is used to prevent nausea and vomiting associated with certain types of cancer chemotherapy and radiation. It is also used to prevent and treat the nausea and vomiting that occurs after surgery. It works by reducing the effects of a naturally-occurring chemical in the body called serotonin, which causes nausea and vomiting.
India has many manufacturers who manufacture Ondansetron Injection USP 8 mg .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Ondansetron Injection USP 8 mg in India.
ADDITIONAL INFORMATION
The recommended dose for children is 3 to 5 mg per square metre of body surface area and will be calculated by your doctor.
SIDE EFFECTS
Contact doctor if patient experience these side effects
Stop taking the medication and seek immediate medical attention if any of the following occur:
Rabipur is a Powder and solvent for solution for injection Rabies vaccine, inactivated
Pharmaceutical Form :
Powder and solvent for solution for injection. A clear colourless solution results after reconstitution of the white freeze-dried powder with the clear and colourless solvent.
Clinical Particulars:
(Therapeutic indicationsa) Pre-exposure prophylaxis (before possible risk of exposure to rabies)b) Post-exposure prophylaxis (after known or possible exposure to rabies)Consideration should be given to national and/or WHO guidance regarding the prevention of rabies.Posology and method of administration Posology. The recommended single intramuscular dose is 1 ml in all age groups.Whenever possible according to vaccine availability, it is recommended that one type of cell culture vaccine should be used throughout the course of pre- or post-exposure immunisation. However, adherence to the recommended schedules is of critical importance for post-exposure prophylaxis, even if another type of cell culture vaccine has to be used.
What RABIPUR looks like ?
Each pack of RABIPUR contains
• one vial of vaccine powder
• one ampoule of sterile water forinjections
•one disposable syringe.
Your doctor will inject the sterilewater into the vial to make the liquidfor your injection. This liquid is clearand colourless.IngredientsVaccineActive ingredients:• Not less than 2.5 InternationalUnits of inactivated Rabies virus(Flury LEP strain)
Other ingredients:• Trometamol• Sodium chloride• Disodium edetate• Monopotassium glutamate• Polygeline• Sucrose• Possible trace amounts:neomycin, chlortetracycline, amphotericin BDiluent• Water for InjectionsThe manufacture of this productincludes exposure to bovine derivedmaterials. No evidence exists thatany case of vCJD (considered to bethe human form of bovinespongiform encephalitis) has resultedfrom the administration of anyvaccine product.Contains no antimicrobial agent.Product is for single use in onepatient only. Discard any residue.
Manufactured by : Novartis Vaccines and Diagnostics GmbH
Azithromycin belongs to the family of medications known as macrolide antibiotics. It is used to treat certain types of infections that are caused by bacteria. It is most commonly used to treat ear infections (e.g., otitis media), throat infections, lung infections (e.g., pneumonia), and skin infections. It can also be used to prevent mycobacterium avium complex (MAC) infections in people with HIV infection.Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and, thus, interfering with microbial protein synthesis. Nucleic acid synthesis is not affected.
SIDE EFFECTS
Gastrointestinal: dyspepsia, flatulence, mucositis, oral moniliasis, and gastritis.
Nervous System: headache, somnolence.
Allergic: bronchospasm.
Special Senses: taste perversion.
Diarrhea, nausea, vomiting, abdominal pain, rash, chest pain; hepatotoxicity, allergy (eg, angioedema, cholestatic jaundice), torsade de pointes (esp. elderly), C. difficile associated diarrhea.
BIVALIRUDIN INJECTION 250 MG
Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). It is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis).Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin.It inhibits both circulating and clot-bound thrombin.It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
ADDITIONAL INFORMATION
Bivalirudin is intended for IV use only and is supplied as a sterile, lyophilized product in single-use, glass vials. After reconstitution, each vial delivers 250 mg of bivalirudin.
SIDE EFFECTS
Very common: More than 1 in 10 people who have Bivalirudin
Common: More than 1 in 100 people who have Bivalirudin
Uncommon: More than 1 in 1000 people who have Bivalirudin
Rare: More than 1 in 10, 000 people who have Bivalirudin
Very rare: Fewer than 1 in 10, 000 people who have Bivalirudin
Merrobe (Meropenem) is prescription drug used to treat serious bacterial infections on various body parts like skin and soft tissues, urinary tract, blood, brain and lungs.
Dosage :
Skin and Structure Infection :
Intraabdominal Infection :
Meningitis :
Nosocomial Pneumonia :
Common side effects Nausea, Vomiting, Seizure.
Polymyxin B Injection 500000 Units is a drug of choice in the treatment of infections of the urinary tract, meninges, and bloodstream caused by susceptible strains of Ps. aeruginosa. It may also be used topically and subconjunctivally in the treatment of infections of the eye caused by susceptible strains of Ps. aeruginosa.It may be indicated in serious infections caused by susceptible strains of the following organisms, when less potentially toxic drugs are ineffective or contraindicated: H influenzae, specifically meningeal infections. Escherichia coli, specifically urinary tract infections. Aerobacter aerogenes, specifically bacteremia . Klebsiella pneumoniae, specifically bacteremia.
3s corporation is Supplier, Exporter , Wholesaler for Polymyxin B Injection 500000 Units in India.
We even offer contract manufacturing services from WHO GMP approved factories.
Intravenous: Dissolve 500, 000 polymyxin B (polymyxin b sulfate) units in 300 to 500 mL solutions for parenteral dextrose injection 5% for continuous drip.
Adults and children: 15, 000 to 25, 000 units/kg body weight/day in individuals with normal kidney function.This amount should be reduced from 15, 000 units/kg downward for individuals with kidney impairment. Infusions may be given every 12 hours; however, the total daily dose must not exceed 25, 000 units/kg/day.
Infants: Infants with normal kidney function may receive up to 40, 000 units/kg/day without adverse effects.
Intramuscular: Not recommended routinely because of severe pain at injection sites, particularly in infants and children. Dissolve 500, 000 polymyxin B units in 2 mL sterile water for injection or sodium chloride injection or procaine hydrochloride injection 1%.
Adults and children: 25, 000 to 30, 000 units/kg/day.This should be reduced in the presence of renal impairment.The dosage may be divided and given at either 4 or 6 hour intervals.
Infants: Infants with normal kidney function may receive up to 40, 000 units/kg/day without adverse effects.
SIDE EFFECTS
Ephrotoxic reactions: Albuminuria, cylin-duria, azotemia, and rising blood levels without any increase in dosage.
Neurotoxic reactions: Facial flushing, dizziness progressing to ataxia, drowsiness, peripheral paresthesias (circumoral and stocking glove), apnea due to concurrent use of curariform muscle relaxants, other neurotoxic drugs or inadvertent overdosage, and signs of meningeal irritation with intrathecal administration, e.g., fever, headache, stiff neck and increased cell count and protein cerebrospinal fluid.
Other reactions occasionally reported: Drug fever, urticarial rash, pain (severe) at intramuscular injection sites, and thrombophlebitis at intravenous injection sites.
Tigecycline Injection 50 mg is a tetracycline derivative (a glycylcycline) for intravenous infusion.It is an antibacterial drug indicated for the treatment of infections listed below for patients 18 years of age and older.
COMPLICATED SKIN AND SKIN STRUCTURE INFECTIONSComplicated skin and skin structure infections caused by Escherichia coli, Enterococcus faecalis (vancomycin-susceptible isolates), Staphylococcus aureus , Streptococcus agalactiae, Streptococcus anginosus grp. (includes S. anginosus, S. intermedius, and S. constellatus), Streptococcus pyogenes, Enterobacter cloacae, Klebsiella pneumoniae, and Bacteroides fragilis.
COMPLICATED INTRA-ABDOMINAL INFECTIONSComplicated intra-abdominal infections caused by Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Enterococcus faecalis (vancomycin-susceptible isolates), Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus anginosus grp. (includes S. anginosus, S. intermedius, and S. constellatus), Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Clostridium perfringens, andPeptostreptococcus micros.
COMMUNITY-ACQUIRED BACTERIAL PNEUMONIACommunity-acquired bacterial pneumonia caused by Streptococcus pneumoniae .
We even offer contract manufacturing services from WHO GMP approved factories.
3s corporation is Supplier, Exporter , Wholesaler for Tigecycline Injection 50 mg in India.
ADDITIONAL INFORMATION
The recommended duration of treatment with Tigecycline Injection 50 mg for complicated skin and skin structure infections or for complicated intra-abdominal infections is 5 to 14 days. The recommended duration of treatment with Tigecycline Injection 50 mg for community-acquired bacterial pneumonia is 7 to 14 days. The duration of therapy should be guided by the severity and site of the infection and the patient’s clinical and bacteriological progress.
SIDE EFFECTS
Get emergency medical help if patient has any of these signs of an allergic reaction:
hives;
difficulty breathing;
swelling of your face, lips, tongue, or throat.
Stop using tigecycline and call your doctor at once if patient has serious side effect such as:
Capreomycin Injection is used with other drugs to treat tuberculosis (TB) infections. Capreomycin belongs to a class of drugs known as antibiotics. Capreomycin is an antibiotic that fights bacteria in the body. It is believed to work by preventing the growth of the bacteria that causes TB. Capreomycin is usually given after other tuberculosis medications have been tried without successful treatment of the infection.
3s corporation is supplier, exporter & wholesaler for Capreomycin Injection in India. We even offer contract manufacturing services from WHO & cGMP approved factories. It is popularly sold in dosage of 750 mg & 1g. It is powder form & comes in vial form with solvent.
ADDITIONAL INFORMATION
This medication is given by injection into a muscle or infused into a vein over 1 hour, usually by a health care professional. It is usually given once a day for 2 to 4 months then reduced to 2 or 3 times a week depending on your condition and response to treatment, or use as directed by your doctor. Dosage is based on your medical condition, kidney function, and response to treatment.
If you are giving this medication by injection into a muscle, remember to change the injection site with each dose to prevent irritation. Also, inject this medication into a large muscle such as the buttock or thigh to lessen pain from the injection.
SIDE EFFECTS
Stop using capreomycin and call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:
Colistimethate sodium injection contains colistimethate sodium. It is an antibiotic that fights serious bacterial infections, especially chest infections and infections of the urinary tract. Colistimethate sodium is used when other more common antibiotics no longer work or cannot be used.
India has many manufacturers who manufacture Colistimethate sodium injection .To know more contact us.
3s corporation is supplier, Exporter, Wholesaler for Colistimethate sodium injection in India.
ADDITIONAL INFORMATION
This medicine does not require any special storage conditions. Colistimethate sodium contains no preservatives. Once prepared, Colistimethate sodium should be used immediately.
SIDE EFFECTS
Colistimethate sodium can sometimes cause allergic reactions like skin rash or red and lumpy skin rash, swollen eyelids, face, lips, mouth or tongue, itching, difficulty breathing or swallowing. If this happens, Colistimethate sodium treatment should be stopped immediately. Colistimethate sodium can also affect your kidneys, especially if the dose is high.
Very common side effects (affecting more than 1 person in 10)are:
• headache
• tingling or numbness around the mouth, lips and face
• itching
• muscle weakness
Rare side effects (affecting less than 1 person in 1 000):
• kidney failure
Other side effects can include:
• dizziness
• difficulty in controlling movements
• soreness at the site of injection
3s corporation is Supplier, Exporter , Wholesaler for Daptomycin Injection 350 / 500 mg in India.
We even offer contract manufacturing services from WHO GMP approved factories.
ADDITIONAL INFORMATION
Daunorubicin hydrochloride is the hydrochloride salt of an anthracycline cytotoxic antibiotic produced by a strain of Streptomyces coeruleorubidus. It is provided as a sterile reddish lyophilized powder in vials for intravenous administration only. Daunorubicin hydrochloride has antimitotic and cytotoxic activity through a number of proposed mechanisms of action. Daunorubicin hydrochloride forms complexes with DNA by intercalation between base pairs. It inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes. Single strand and double strand DNA breaks result.
There are many generic manufacturers in India who manufacture Daunorubicin Hydrochloride Injection USP 20 mg including United Biotech(P) Ltd etc.
3s corporation is Supplier, Exporter , Wholesaler for Daunorubicin Hydrochloride Injection USP 20 mg in India.
ADDITIONAL INFORMATION
Daunorubicin Hydrochloride in combination with other approved anticancer drugs is indicated for remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults. The reconstituted solution is stable for 24 hours at room temperature and 48 hours under refrigeration.
Starting Doses :The recommended dosage in each individual may vary from 0.5 to 3 mg/ kg.
Acute non-lymphoytic leukemiaPatients <60 yrs. of age : 45mg/m2/day.
Patients >60 yrs. of age : 30mg/m2/day.
Acute Lymphocytic Leukemia (ALL)Paediatric : 25mg/m2
Adult : 45mg/m2
SIDE EFFECTS
Rarely, anaphylactoid reaction, fever, and chills can occur. Hyperuricemia may occur, especially in patients with leukemia, and serum uric acid levels should be monitored.
BONE MARROWDaunorubicin Hydrochloride Injection is a potent bone marrow suppressant. Suppression will occur in all patients given a therapeutic dose of this drug. Therapy withDaunorubicin Hydrochloride Injection should not be started in patients with pre-existing drug-induced bone marrow suppression unless the benefit from such treatment warrants the risk. Persistent, severe myelosuppression may result in superinfection or hemorrhage.
Doxycycline hyclate is a broad spectrum antibiotic derived from oxytetracycline. inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Doxycycline has bacteriostatic activity against a broad range of Gram-positive and Gram- negative bacteria.
3s corporation is supplier, Exporter , Wholesaler for Doxycyclin Injection 100 mg in India.
We even offer contract manufacturing services from WHO GMP approved factories
ADDITIONAL INFORMATION
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Doxycycline for Injection, USP and other antibacterial drugs, doxycycline for injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
SIDE EFFECTS
nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. Hepatotoxicity has been reported rarely. These reactions have been caused by both the oral and parenteral administration of tetracyclines.
SKINMaculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon.
RENAL TOXICITYRise in BUN has been reported and is apparently dose related
HYPERSENSITIVITY REACTIONSUrticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, pericarditis and exacerbation of systemic lupus erythematosus.
Bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. These conditions disappeared rapidly when the drug was discontinued.
BLOODHemolytic anemia, thrombocytopenia, neutropenia and eosinophilia have been reported.
When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function studies are known to occur.
Teicoplanin Injection 200 & 400 mg is an antibiotic. It contains a medicine called ‘teicoplanin’. It works by killing the bacteria that cause infections in your body.Targocid is used in adults and children (including newborn babies) to treat bacterial infections of:
We even offer contract manufacturing services from WHO GMP approved factories.
3s corporation is Supplier, Exporter , Wholesaler for Teicoplanin Injection 200 & 400 mg in India.
ADDITIONAL INFORMATION
This medicine will normally be given by a doctor or nurse.
Tell doctor or nurse straight away, if any of the following serious side effects are noticed
Uncommon (may affect up to 1 in 100 people)
Not known (frequency cannot be estimated from the available data)
Other side effects
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1, 000 people)
Not known (frequency cannot be estimated from the available data)
Vasopressin Injection 20 & 40 IU is used to control the frequent urination, increased thirst, and loss of water caused by diabetes insipidus. This is a condition that causes the body to lose too much water and become dehydrated. Vasopressin injection is also used to prevent and treat abdominal or stomach distension that occurs after surgery. It is also used in abdominal or stomach roentgenography.
There are many generic manufacturers in India who manufacture Vasopressin Injection 20 & 40 IU including Health Biotech Pvt Ltd etc.
3s corporation is Supplier, Exporter , Wholesaler for Vasopressin Injection 20 & 40 IU in India.
SIDE EFFECTS
Side Effects include
Pallor,
Vomiting, nausea, belching,
Abdominal cramps,
Tremour, pounding headache, vertigo, fluid retention,
Hyponatraemia,
Hypersensitivity reaction, sweating,
Urticaria, gangrene, desire to defecate, arrhythmias, bradycardia, angina, MI and bronchoconstriction.
Potentially Fatal: Anaphylaxis; cardiac arrest or shock.
Tranaxamic Acid Injection 100 mg / ml is used in Local fibrinolysis for short term use in prophylaxis and treatment in patients at high risk of per – and post-operative haemorrhage following prostatectomy, conisation of the cervix and surgical procedures and dental extractions in haemophiliacs. It is also used in General fibrinolysis that is haemorrhagic complications in association with thrombolytic therapy and haemorrhage associated with disseminated intravascular coagulation with predominant activation of the fibrinolytic system.
India has many manufacturers who manufacture Tranaxamic Acid Injection 100 mg .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Tranaxamic Acid Injection 100 mg in India.
SIDE EFFECTS
Very rare side effect have been reported:
• Gastro-intestinal disorders: digestive effects such as nausea, vomiting and diarrhoea.
• Cardio-vascular disorders:
• malaise with hypotension, with or without loss of consciousness (generally following a too fast intravenous injection, exceptionally after oral administration)
• arterial or venous thrombosis at any sites
• Nervous system disorders: dizziness; convulsions, particularly in case of misuse.
• General disorders: hypersensitivity reactions including anaphylaxis.
Amphotericin B Lipid Complex injection 10, 25, 50 & 100 mg is used in treatment of invasive fungal infections in patients refractory to conventional amphotericin B therapy.It act by altering fungal cell membrane permeability by binding to the sterol component of the cell membrane.
There are many generic manufacturers in India who manufacture Amphotericin B Lipid Complex injection10, 25, 50 & 100 mg including United biotech etc.
3s corporation is Supplier, Exporter , Wholesaler for Amphotericin B Lipid Complex injection 10, 25, 50 & 100 mg in India.
ADDITIONAL INFORMATION
For Systemic Fungal Infections in Adults and Children IV dose of 5 mg/kg/day as a single infusion is given.
In case of Renal Function Impairment (CrCl less than 10 mL/min)dose of 5 mg/kg every 24 to 36 h is given.
SIDE EFFECTSPhlebitis (25%); hypertension, tachycardia (23%); hypotension (22%); chest pain (12%); cardiac arrest (6%); vasodilatation (5%); atrial fibrillation, bradycardia, cardiac arrest, cardiomegaly, hemorrhage, postural hypotension, valvular heart disease, vascular disorder (2% to 10%); cardiovascular disorder (at least 5%); CHF, shock, supraventricular tachycardia, syncope, ventricular extrasystoles (1% to less than 5%); MI, shock, tachypnea.
CNSInsomnia (22%); headache (21%); anxiety (14%); asthenia, confusion (13%); dizziness (10%); abnormal thinking, agitation, coma, convulsions, depression, dysesthesia, hallucinations, malaise, nervousness, paresthesia, somnolence, tremor (2% to 10%); hypertonia, neuropathy, psychosis, speech disorder, stupor (1% to less than 5%); cerebral vascular accident, diplopia, encephalopathy, extrapyramidal syndrome, peripheral neuropathy, transient vertigo.
DERMATOLOGICRash (25%); pruritus, sweating (11%); alopecia, dry skin, herpes simplex, maculopapular rash, purpura, skin discoloration, skin disorder, skin ulcer, urticaria, vesiculobullous rash (2% to 10%); acne, petechial rash, skin nodule (1% to less than 5%); erythema, erythema multiforme, exfoliative dermatitis, flushing.
EENTConjunctivitis, dry eyes, eye hemorrhage, pharyngitis (2% to 10%); amblyopia, deafness, ear disorder, tinnitus (1% to less than 5%); visual impairment.
GIVomiting (44%); nausea (40%); diarrhea (30%); abdominal pain (22%); constipation (21%); anorexia (14%); GI hemorrhage, nausea and vomiting (11%); abdomen enlarged, dry mouth/nose, dyspepsia, dysphagia, eructation, fecal incontinence, flatulence, hemorrhoids, gum/oral hemorrhage, hematemesis, ileus, mucositis, rectal disorder, stomatitis, ulcerative stomatitis (2% to 10%); bloody diarrhea, GI disorder, gingivitis, glossitis, increased GGT, melena, mouth ulceration, oral moniliasis, rectal disorder (1% to less than 5%); cramping, epigastric pain.
GENITOURINARYNephrotoxicity (63%); hematuria (14%); kidney failure (5%); abnormal renal function, acute kidney failure, acute renal failure, dysuria, toxic nephropathy, urinary incontinence, vaginal hemorrhage (2% to 10%); albuminuria, glucosuria, oliguria, urinary retention, urinary tract disorder (1% to less than 5%); anuria, azotemia, decreased renal function, hemorrhagic cystitis, hyposthenuria, impotence, nephrocalcinosis, renal tubular acidosis.
HEMATOLOGIC-LYMPHATICAnemia (48%); leukopenia (17%); thrombocytopenia (13%); coagulation disorder, decreased or increased prothrombin, ecchymosis, fluid overload, petechiae (2% to 10%); decreased thromboplastin, hypochromic anemia, increased fibrinogen, leukocytosis (1% to less than 5%); blood dyscrasias including coagulation defects, eosinophilia, normochromic or normocytic anemia; agranulocytosis (postmarketing).
HEPATICBilirubinemia (19%); increased ALT (15%); abnormal LFTs, increased AST (13%); hepatocellular damage, hepatomegaly, veno-occlusive liver disease (2% to 10%); jaundice (at least 5%); liver failure (1% to less than 5%); cholangitis, cholecystitis, hepatitis.
HYPERSENSITIVITYAllergic reaction (2% to 10%); anaphylactic and anaphylactoid reactions, bronchospasm, hypersensitivity pneumonitis, wheezing.
LOCALInjection-site inflammation (2% to 10%); injection-site pain, injection-site reaction (1% to less than 5%); thrombophlebitis.
METABOLIC-NUTRITIONALHypokalemia (51%); hypomagnesemia, increased creatinine (49%); increased BUN (31%); hyperglycemia (28%); increased alkaline phosphatase (22%); hypocalcemia (21%); peripheral edema (17%); edema, hypervolemia (15%); hyponatremia (12%); hypernatremia (11%); acidosis, hyperchloremia, hyperkalemia, hypermagnesemia, hyperphosphatemia, hypophosphatemia, hypoproteinemia, increased amylase, increased LDH, increased nonprotein nitrogen, respiratory alkalosis (2% to 10%); weight gain (at least 5%); dehydration, hyperlipidemia, hypoglycemia, weight loss (1% to less than 5%); hyperamylasemia, hyperuricemia.
MUSCULOSKELETALBack pain (12%); arthralgia, bone pain, dystonia, myalgia, neck pain, rigors (2% to 10%); myasthenia including bone, joint, and muscle pain.
RESPIRATORYDyspnea (29%); increased cough (22%); hypoxia (21%); epistaxis (20%); lung disorder (18%); pleural effusion (13%); rhinitis (11%); respiratory failure (8%); apnea (at least 5%); hyperventilation (5%); asthma, atelectasis, hemoptysis, hiccup, lung edema, pneumonia, respiratory insufficiency, sinusitis (2% to 10%); respiratory disorder (1% to less than 5%); bronchospasm, cyanosis/hypoventilation, pulmonary edema (postmarketing).
MISCELLANEOUSChills/rigors (90%); chills (77%); fever (58%); blood product transfusion reaction (19%); pain, sepsis (14%); infection (13%); multiple organ failure (11%); procedural complications (10%); cell-mediated immunological reaction, cellulitis, face edema, graft-versus-host disease, influenza-like symptoms (2% to 10%); chills/fever (7%); mucous membrane disorder (at least 5%); death, hypothermia, immune system disorder (1% to less than 5%); angioedema (postmarketing).
Caspofungin acetate Injection is indicated in adults and pediatric patients (3 months and older) for teatment of Empirical therapy for presumed fungal infections in febrile, neutropenic patients, Treatment of candidemia and the othervCandida infections i.e. intra-abdominal abscesses, peritonitis andpleural space infections. It is also used in treatment of esophagealcandidiasis , invasive aspergillosis in patients who are refractoryto or intolerant of other therapies . Caspofungin acetate is an echinocandin that inhibits the synthesis of β (1, 3)-D-glucan, an integral component of the fungal cell wall.
India has many manufacturers who manufacture Caspofungin acetate Injection .
ADDITIONAL INFORMATION
Anaphylaxis has been reported during administration of CANCIDAS. If this occurs, CANCIDAS should be discontinued and appropriate treatment administered.
SIDE EFFECTS
Serious side effect includes:
Fungizone IV Injection contains Amphotericin B which is an antifungal drug . It is used intravenously help the body overcome serious fungus infections. It is manufactured by Emcure in India. It comes in single vial packing.
SIDE EFFECTS
Side Effects include Fever and chills , headache, increased or decreased urination, irregular heartbeat, muscle cramps or pain, nausea, pain at the place of injection, unusual tiredness or weakness, vomiting.
Voriconazole Injection 100 & 200 mg is used as antifungal agent .It is indicated for use in patients 12 years of age and older in the treatment of infections such as Invasive Aspergillosis, Esophageal Candidiasis andis also used in disseminated Infections In Skin and infections in Abdomen, Kidney, Bladder Wall, And Wounds.
India has many manufacturers who manufacture Voriconazole Injection 100 & 200 mg .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Voriconazole Injection 100 & 200 mg in India.
SIDE EFFECTS
Somatostatin Injection is a peptide hormone, prescribed for gastrointestinal hemorrhage. Somatostatin (also known as growth hormone-inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF)) or somatotropin release-inhibiting hormone is a peptide harmone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein – coupled somatostatin and inhibition of the release of numerous secondary hormones. Somatostatin is used in treatment of severe acute gastrointestinal hemorrhage, resulting from gastric or duodenal ulcers, hemorrhagic gastritis and esophageal varices, biliary and pancreatic fistulae.
India has many manufacturers who manufacture Somatostatin Injection .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Somatostatin Injection in India.
ADDITIONAL INFORMATION
Somatostatin Injection is contraindicated in Hypersensitivity.
SIDE EFFECTS
Cardiac Disorders: atrioventricular block, bradycardia, arrhythmia, ventricular extrasystole.
Gastrointestinal Disorders: abdominal pain, diarrhea, nausea, vomiting.
Metabolism and Nutrition Disorders: hyperglycaemia, hypoglycaemia.
Vascular Disorders: hypertension, hypotension, hot flushes.
Abrupt interruption of continuous infusion may result in a rebound effect of the treated disease, especially in patients treated for fistula.
DESCRIPTION
Iopromide Injection is a nonionic, water soluble x-ray contrast agent for intravascular administration. Iopromide injection is used to help diagnose or find problems in the brain, heart, head, blood vessels, and other parts of the body. It is an iodinated contrast agent. Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures such as CT scans and angiography.
3s corporation is Supplier, Exporter , Wholesaler for Iopromide Injection in India.
We even offer contract manufacturing services from WHO GMP approved factories.
ADDITIONAL INFORMATION
A doctor or other trained health professional will give this medicine to patient in a hospital. This medicine is given through a needle placed in an artery or a vein.
Patient should drink extra fluids so that he will pass more urine while receiving this medicine. This may help prevent kidney problems.
SIDE EFFECTS
Acyclovir Injection is anti viral agent, active against herpes simplex virus and to less extent varicella-zoster virus. It Inhibits viral DNA polymerase and viral DNA replication. Resistant herpes simplex virus to aciclovir has been reported.Aciclovir Powder for Solution for Infusion is indicated for the prophylaxis and treatment of Herpes simplex infections in immunocompromised patients. It is also used for the treatment of severe initial genital herpes in the nonimmunocompromised, Herpes simplex infections in the neonate and infant up to three months of age, herpes encephalitis, and Varicella zoster infections.
There are many generic manufacturers in India who manufacture Acyclovir including Cipla, Glaxosmithkline, RPG etc.
ADDITIONAL INFORMATION
The dose of acyclovir for infusion must be adjusted in patients with impaired renal function in order to avoid accumulation of acyclovir in the body (see Dosage in renal impairment). In patients receiving aciclovir for infusion at higher doses (e.g. for herpes encephalitis), specific care regarding renal function should be taken, particularly when patients are dehydrated or have any renal impairment. For reconstituted solutions, the shelf life is 24 hours at a temperature of 2-8°C. The storage instruction is ‘Do not store above 25°C’.
SIDE EFFECTS
Gastrointestinal: Nausea and vomiting have been reported.
Haematological: Decreases in haematological indices (anaemia, thrombocytopenia, leucopenia).
Hypersensitivity and Skin: Rashes including photosensitivity, urticaria, pruritus, fevers and rarely dyspnoea, angioedema and anaphylaxis. Severe local inflammatory reactions sometimes leading to breakdown of the skin have occurred when formulations of aciciovir for intravenous use have been inadvertently infused into extravascular tissues.
Kidney: Rapid increases in blood urea and creatinine levels may occasionally occur in patients given aciclovir for infusion. This is believed to be related to peak plasma levels and the state of hydration of the patient. To avoid this effect the drug should not be given as an intravenous bolus injection but by slow infusion over a one hour period. Adequate hydration of the patient should be maintained. Renal impairment developing during treatment with aciclovir for infusion usually responds rapidly to rehydration of the patient and/or dosage reduction or withdrawal of the drug. Progression to acute renal failure, however, can occur in exceptional cases.
Liver: Reversible increases in bilirubin and liver-related enzymes. Hepatitis and jaundice have been reported on very rare occasions.
Bleomycin for Injection, USP is a mixture of cytotoxic glycopeptide antibiotics isolated from a strain of Streptomyces verticillus and is freely soluble in water. It is available as a lyophilized powder for intramuscular, intravenous or subcutaneous injection. Each vial contains sterile bleomycin sulfate equivalent to 15 units or 30 units of bleomycin. Sulfuric acid or Sodium hydroxide used, if necessary to adjust the pH.
Bleomycin for Injection has been shown to be useful in the management of Squamous Cell Carcinoma , Lymphomas and Testicular Carcinoma.
It is manufactured & exported by many Indian manufacturers including brands like Cipla, Cadila, Klab, Neon etc.
ADDITIONAL INFORMATION
Intramuscular or Subcutaneous:The bleomycin for injection, USP 15 units vial should be reconstituted and dissolved with 1 to 5 mL of sterile water for injection, USP, sodium chloride injection, 0.9%, USP, or bacteriostatic water for injection, USP. The bleomycin for injection, USP 30 units vial should be reconstituted and dissolved with 2 to 10 mL of the above diluents.Intravenous: The contents of the 15 units or 30 units vial should be dissolved in 5 mL or more or 10 mL or more, respectively of sodium chloride injection, 0.9%, USP, and administered slowly over a period of 10 minutes
SIDE EFFECTS
Pulmonary toxicities occur in 10% of treated patients. In approximately 1%, the nonspecific pneumonitis induced by bleomycin progresses to pulmonary fibrosis, and death. Although this is age and dose related, the toxicity is unpredictable. Frequent roentgenograms are recommended.
A severe idiosyncratic reaction (similar to anaphylaxis) consisting of hypotension, mental confusion, fever, chills, and wheezing has been reported in approximately 1% of lymphoma patients treated with bleomycin. Since these reactions usually occur after the first or second dose, careful monitoring is essential after these doses .
Renal or hepatic toxicity, beginning as a deterioration in renal or liver function tests, have been reported, infrequently. These toxicities may occur, however, at any time after initiation of therapy.
This medication is a synthetic prostaglandin analogue, prescribed for termination of pregnancy and also used for postpartum hemorrhage. It induces uterine muscle contractions and can trigger abortion in early pregnancy. Carboprost is a uterine stimulant which results in expulsion of the products of conception. It is also used to induce abortion between 13-20 Wk of pregnancy. It produces myometrial contractions responsible for placental hemostasis.
It is manufactured by many Indian manufacturers such as Neon Laboratories Ltd and Astra Zeneca Pharma India Limited.
3s corporation is supplier, Exporter for Carboprost 125 & 250 mcg Injection in India.
ADDITIONAL INFORMATION
Examine cervix after abortion for cervical trauma.
Not recommended in the presence of choriamionitis, recourse to surgery may be considered.
SIDE EFFECTS
Most Common- Nausea, vomiting, diarrhea and excessive uterine bleeding.
Less Common- Abdominal pain, flushing, shivering, headache, dizziness, hypotension, fever/chills, difficulty in breathing and lung swelling.
DESCRIPTION
Bravelle® is a product containing a highly purified preparation of human follicle stimulating hormone (hFSH) extracted from the urine of postmenopausal women. Human FSH consists of two non-covalently linked glycoproteins designated as the α and β subunits. The α subunit has 92 amino acids of which two are modified by attachment of carbohydrates. The β subunit has 111 amino acids of which two are modified by attachment of carbohydrates.Bravelle® is a sterile, lyophilized powder intended for subcutaneous (SC) or intramuscular (IM) injection after reconstitution with sterile 0.9% Sodium Chloride Injection, USP. Each vial of Bravelle® contains 82.5 International Units (IU) of Follicle Stimulating Hormone (FSH) activity, 23 mg Lactose Monohydrate, 0.005 mg Polysorbate 20, and Sodium Phosphate buffer (Sodium Phosphate dibasic, Heptahydrate and Phosphoric acid) for pH adjustments, which, when reconstituted with diluent, will deliver 75 IU of FSH. Bravelle® contains up to 2% luteinizing hormone (LH) activity based on bioassay. Human Chorionic Gonadotropin (hCG) is not detected in Bravelle®. When stored at 3° to 25°C, up to 40% of the α-subunits may be oxidized.The in vivo biological activity of urofollitropin for injection, purified is determined by using reference standards calibrated against the First International Standard for follicle-stimulating hormone, (FSH, Urofollitropin), Urinary, Human for Bioassay, National Institute for Biological Standards and Control (NIBSC) at its 46th meeting in 1995.
ADDITIONAL INFORMATION
Directions for Using Bravelle®Wash hands thoroughly with soap and water.Before injections, the septum tops of the vials should be wiped with an aseptic solution to prevent contamination of the contents.To prepare the Bravelle® solution, inject 1 mL of Sterile Saline for Injection, USP into the vial of Bravelle®. DO NOT SHAKE, but gently swirl until the solution is clear. Generally, the Bravelle® dissolves immediately. Check the liquid in the container. If it is not clear or has particles in it, DO NOT USE IT.For patients requiring a single injection from multiple vials of Bravelle®, up to 6 vials can be reconstituted with 1 mL of Sterile Saline for Injection, USP. This can be accomplished by reconstituting a single vial as described above (see step 3). Then draw the entire contents of the first vial into a syringe, and inject the contents into a second vial of lyophilized Bravelle®. Gently swirl the second vial, as described above, once again checking to make sure the solution is clear and free of particles. This step can be repeated with 4 additional vials for a total of up to 6 vials of lyophilized Bravelle® into 1 mL of diluent.Immediately ADMINISTER the reconstituted Bravelle® either SC (for ovulation induction or multifollicular development during ART) or IM (for ovulation induction). Any unused reconstituted material should be discarded.Draw the reconstituted Bravelle® into an empty, sterile syringe.Hold the syringe pointing upwards and gently tap the side to force any air bubbles to the top; then squeeze the plunger gently until all the air has been expelled and only Bravelle® solution is left in the syringe.Bravelle® works if it is injected SC (for ovulation induction or multifollicular development during ART) or IM (for ovulation induction). The recommended sites for SC injection are either side of the lower abdomen in alternating fashion with the actual injection site varied a little with each injection. SC injection of Bravelle® into the thigh is not recommended unless the lower abdomen is not usable because of scarring, surgical deformity or other medical conditions.
Hucog Injection is manufactured by Bharat Serum & is Chorionic Gonadotropin Injection. In the female, HUCOG HP is used in the treatment of anovulatory infertility. where its administration would form part of recognized treatment regimen involving prior stimulation of follicular maturation and endometrial proliferation e.q. with Menotropin Injection (HUMOG HP). Hypogonadotrophin hypogonadism and cryptorchidism :
In the male, HUCOG HP stimulates the interstitial cells of the testes and consequently the secretion of androgens and the development of secondary sexual characteristics. With concomitant Menotropin Injection therapy, HUCOG HP stimulates the induction and maintenance of spermatogenesis.
ADDITIONAL INFORMATION
Dosage and Administration :
HUCOG HP is given by subcutaneous / intramuscular injection only. Anovulatory infertility :HUCOG HP 10000 I.U. is administered in mid-cycle, following treatment with Menotropin Inj. (HUMOG HP) according to a recognised scheme. Details of Menotropin Inj. (HUMOG HP) dosage and monitoring are available on request.
Hypogonadotrophic hypogonadism :HUCOG HP 2000 I.U. twice weekly concomitant with Menotropin Inj. (HUMOG HP) (1 vial three times a week) if necessary for a minimum period of four months.
Menogon (Menotrophin injection) a prescription drug manufactured by Ferring is purified combination of follicle stimulating hormone (FSH) and luteinizing hormone (LH) extracted from the urine of post menopausal women. Menogon is administered as an intramuscular or a subcutaneous injection to treat infertility, to induce ovulation and enable pregnancy in women. It may also be used to stimulate the production of sperm in certain forms of male infertility.
ADDITIONAL INFORMATION
Unless prescribed otherwise, doses are as follows:
Sterility in Females: The dosage of HMG for the induction of follicle growth in normo- or hypogonadotrophic women varies according to the individual.The amount depends on ovarian reaction and should be checked by ultrasound examinations of the ovaries and measuring estradiol levels. If the HMG dosage is too high for the treated individual, multiple uni- and bilateral follicle growth can occur.HMG is administered IM or SC and in general, the therapy is begun with a daily dosage corresponding to 75-150 iu FSH. If the ovaries do not respond, the dosage can slowly be increased until a rise in estradiol secretion and follicle growth is evident. Treatment with the same dosage of HMG continues until the preovulatory estradiol serum level is attained. If the level rises too quickly, the dosage should be reduced. To induce ovulation, hCG 5000 or 10, 000 iu are injected IM 1-2 days after the last HMG administration.Note: After administering a HMG dosage which is too high for the corresponding individual, a subsequent hCG administration can cause an unintentional hyperstimulation of the ovaries.
Sterility in Males: Initially, 3 x 1000 and 3000 iu hCG a week are administered until a normal testosterone serum level is reached. Then, an additional dose of HMG 3 x (75-150 iu FSH + 75-150 iu LH)/week is administered IM for a few months.
Drug Interactions:
Interactions with other medications are unknown. HMG can be injected together with hCG when treating infertile males.
Storage:
Store and protect from light. Menogon should not be stored at temperatures exceeding +25°C.
SIDE EFFECTS
Occasionally, nausea and vomiting can occur.In single cases, hypersensitivity reactions and fever can occur during treatment with HMG. The administration of Menogon may lead to reactions at the injection site: Reddening, pain, swelling and itching. In very rare cases, long-term usage can lead to the formation of antibodies, making the therapy ineffective.Treatment with HMG can often lead to ovarian hyperstimulation that first becomes clinically relevant after the administration of hCG (pregnancy hormone) to induce ovulation. This can lead to the formation of large ovarian cysts that tend to rupture and to intra-abdominal bleeding.In addition, the accumulation of fluids in the abdominal cavity (ascites), the accumulation of fluids in the chest cavity (hydrothorax), a decrease in the excretion of urine (oliguria), lowering of the blood pressure (hypotension), and occlusion of blood vessels by blood clots (thromboembolic phenomena) can occur. Treatment should be immediately discontinued when the first signs of hyperstimulation appear: Abdominal pain and a palpable (by the physician) enlargement in the lower abdomen, which can be detected sonographically.If abdominal pain occurs, see the doctor.With pregnancy, these side effects can intensify, continue over a long period of time, and be life threatening.Unintentional multiple pregnancies occur more often during treatment with HMG.
Pregnyl (Preg-nil) is a medicine which is used in female infertility, male infertility, delayed puberty and androgen deficiency. Pregnyl contains chorionic gonadotrophin human. It is supplied by Organon Laboratories Limited.
ADDITIONAL INFORMATION
Pregnyl contains a hormone called human chorionic gonadotrophin. In men Pregnyl increases the production of testosterone and may be used to treat androgen deficiency, delayed puberty or infertility. In women Pregnyl is used in the treatment of infertility or as part of a programme of treatment in assisted reproduction. Assisted reproduction increases the chances of having a multiple pregnancy. You should discuss multiple pregnancy with your prescriber if you are considering having Pregnyl as part of a programme of treatment of assisted reproduction.Pregnyl needs to be injected. Your prescriber or another healthcare professional may give you your injections. If you are going to have this medicine for a long time or if you need to have injections very often your prescriber will show you how to inject this medicine yourself. If you are injecting this medicine yourself then follow the instructions from your prescriber.There should also be instructions on how to inject this medicine in the Patient Information Leaflet that comes with this medicine or on the pharmacy label.The pharmacy label on your medicine tells you how much medicine you should have. It also tells you how often you should have your medicine. This is the dose that you and your prescriber have agreed you should have. You should not change the dose of your medicine unless you are told to do so by your prescriber.Do not share your medicine with other people. It may not be suitable for them and may harm them.If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.
Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:
Thiocolchicoside Injection 4 mg is a muscle relaxant with anti-inflammatory and analgesic effects.It acts as a competitive GABA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.
There are many generic manufacturers in India who manufacture Thiocolchicoside Injection 4 mg including Zydus Synovia (Zydus Cadila Healthcare Ltd) etc.
3s corporation is Supplier, Exporter , Wholesaler for Thiocolchicoside Injection 4 mg in India.
ADDITIONAL INFORMATION
Thiocolchicoside is broken down in the body to a metabolite called 3-demethythiocolchicine (also known as SL59.0955 or M2) that could damage dividing cells therefore inducing toxicity in the embryo, neoplastic changes and fertility reduction in males. Therefore recommended oral dose should not exceed 7 days and intramuscular dose duration should not exceed 5 days.
SIDE EFFECTS
Side effect of thiocolchicoside can include
nausea,
somnolence,
allergy and
vasovagal reactions.
Although muscle relaxant have major side effect of Sedation, but Thiocholchicoside is free from sedation effect possible due to non-interference with nicotinic receptors.
Piracetam Injection 400 mg is a psychotropic agent which acts directly on the brain to improve the efficacy of the telencephalon in both normal subjects and those suffering from some functional deficit. This area of the brain is involved in cognition and also has a role to play in teaming and memory, in alertness and in consciousness. Piracetam does not produce either sedation or stimulation. Piracetam can act on the Central Nervous System in a variety of ways. It will modify neurotransmission within the brain, and can help to improve the metabolic environment essential for good neuronal function. It is also a ha emorrheo logical agent and can improve microcirculation without producing vasodilation. When given as acute or long term treatment for patients suffering from a tunctional CNS deficit, or after cerebral trauma such as hypoxia or intoxication, and after electroshock therapy, it will heighten alertness and increase cognitive function. These changes are seen as a significant increase in the alpha and beta activity, with a reduction in delta activity on an EEG trace.
3s corporation is Supplier, Exporter , Wholesaler for Piracetam Injection 400 mg in India.
We even offer contract manufacturing services from WHO GMP approved factories.
ADDITIONAL INFORMATION
All dosage forms of the product should be stored in a dry place at room temperature (15-25ºC)
SIDE EFFECTS
The side effects reported in connection with Piracetam Injection 400 mg include
nervousness, agitation, irritability, anxiety and sleep disturbances.
The incidence of these during clinical trials was 5% or less and they were more often noted in the older patients taking more than 2.4 g daily. In the majority of cases a dose reduction sufficed to make these symptoms disappeared.
Some patients may complain of fatigue or drowsiness. Gastro-intestinal problems such as nausea, vomiting, diarrhoea and stomachache have also been reported, but their Incidence during clinical trials was 2% or less.
Other symptoms, such as vertigo, headaches, trembling and sexual stimulation have occasionally been reported.
Ketoprofen is a nonsteroidal anti-inflammatory agent possessing anti-inflammatory, analgesic and antipyretic properties. Ketoprofen belongs to the propionic acid subclass of carboxylic acid derivative nonsteroidal antiinflammatory drugs, Ketoprofen has a high affinity for inflamed tissue, resulting in a therapeutic response which lasts considerably longer than can be predicted from the relatively short plasma half-life.
3s corporation is Supplier, Exporter , Wholesaler for Ketoprofen Injection 100 mg in India.
India has many manufacturers who manufacture Ketoprofen Injection 100 mg .To know more contact us.
SIDE EFFECTS
In common with all NSAIDs, due to their action of inhibition of prostaglandin synthesis, there can be the possibility in certain individuals of gastric or renal intolerance. Allergic reactions may occur very rarely.
LORNOXICAM INJECTION 8 MG
Lornoxicam Injection 8 mg is a nonsteroidal anti-inflammatory drug (NSAID).It is prescribed for moderate to severe pain, osteoarthritis and rheumatoid arthritis.
India has many manufacturers who manufacture Lornoxicam Injection 8 mg .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Lornoxicam Injection 8 mg in India.
ADDITIONAL INFORMATION
For IV/IM- Pain: 8 mg 1-2 times/day. Max: 24 mg/day dose is given.
Lornoxicam Injection 8 mg is contraindicated in patients with peptic ulcer, severe kidney impairment, and hypersensitivity.
SIDE EFFECTS
Gastrointestinal – Abdominal pain, diarrhea, indigestion, nausea, vomiting, inflammation of pancreas, and mouth ulcer.
Central Nervous System – Headache, drowsiness, sleeplessness, and dizziness.
Eye and ENT – Visual disturbance, ringing in ear and sensitivity to light.
Heart – High blood pressure, palpitations and fluid retention.
Genitourinary – Kidney damage.
Skin – Skin death and rash.
Humatrope also known as somatropin is used to treat growth failure in children and adults who lack natural growth hormone, and in those with chronic kidney failure, Noonan syndrome, Turner syndrome, short stature at birth with no catch-up growth, and other causes. It is also used to prevent severe weight loss in people with AIDS, or to treat short bowel syndrome.ts amino acid sequence is identical to that of human growth hormone of pituitary origin (anterior lobe). Humatrope is synthesized in a strain of E. coli modified by the addition of a gene for human growth hormone.
It is manufactured by Eli Lilly in powder form and used as injection. It is available in different dosages 6 mg, 12 mg & 24 mg cartridges, 5 mg prefilled syringe & 48 mg PFS for hospitals.
Indications for Humatrope:
Humatrope® (somatropin [rDNA origin] for injection) is used to treat children who are short or growing slowly because they:
ADDITIONAL INFORMATION
Important Safety Information for Humatrope
WHO SHOULD NOT TAKE HUMATROPE?
You should not take Humatrope if you are having serious complications after undergoing open heart surgery, abdominal surgery, serious injuries involving many body systems, or life–threatening breathing problems. Deaths have been reported in such cases.Growth hormone should not be used in children with Prader–Willi syndrome who are severely obese or have a history of severe breathing problems. Deaths have been reported in children with Prader–Willi syndrome who are severely obese, have a history of blocked upper airways, sleep apnea (pauses in breathing during sleeping), or other severe breathing problems. Humatrope has not been approved for the treatment of patients with Prader–Willi syndrome.Humatrope should not be used if you have active cancer. Because growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland, the presence of these types of tumors should be ruled out by your doctor before you start Humatrope.Humatrope should not be used in children whose growth plates in their bones have closed.Humatrope should not be used in adults or children with diabetic retinopathy.If you are allergic to metacresol or glycerin, you should not mix Humatrope with the supplied diluent. Reactions at the injection site are the most common allergic reactions. If you have had an allergic reaction to growth hormone, you should not take Humatrope.
WHAT SHOULD I TELL MY DOCTOR BEFORE TAKING HUMATROPE?Tell your doctor if you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted while taking Humatrope.There have been reports of death in children with Prader–Willi syndrome who recently started growth hormone therapy and had one or more of the following risk factors: obesity, history of severe breathing problems or sleep apnea (pauses in breathing during sleeping), or unidentified respiratory infection. Boys with one or more of these risk factors may be at greater risk than girls. A child with Prader–Willi syndrome should be evaluated by a doctor for signs of severe breathing problems or sleep apnea before starting growth hormone therapy.If you have pre–existing tumors or growth hormone deficiency caused by abnormalities in the brain, you should be watched closely for worsening or returning of this condition. If you had cancer as a child and received radiation treatment to your head, you may have a greater risk of developing a new tumor if you are treated with growth hormone. The most common type of tumor reported in people treated with growth hormone after radiation to the head was a tumor of the covering of the brain, called a meningioma. If you developed growth hormone deficiency because you had a tumor inside the head or received radiation to the head, you should be monitored closely by your doctor during treatment with growth hormone. Children who have some rare genetic conditions may have a greater risk of developing a tumor if treated with growth hormone. If you have moles on your skin you should have these checked carefully for any changes while being treated with growth hormone.Your doctor should check your blood sugar regularly while you are taking Humatrope, especially if you have risk factors for diabetes. If you have diabetes or impaired glucose tolerance, your doctor should monitor your blood sugar closely during Humatrope therapy. New cases of type 2 diabetes have been reported in patients taking Humatrope.Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving growth hormone. Consult a doctor if you develop abdominal pain while taking Humatrope.Tell your doctor if you have any visual changes accompanied by headache, nausea, and/or vomiting while taking Humatrope. This may be a sign of increased pressure in the brain.Adults may retain water during therapy with Humatrope. This may be brief but may increase with higher doses of Humatrope.If you have hypopituitarism and are on standard hormone replacement therapy, your doctor should monitor your hormone replacement therapy closely while taking Humatrope.You should have your thyroid function tested periodically during Humatrope therapy. Thyroid hormone treatment may need to be started or adjusted.Slipped capital femoral epiphysis (fracture in the ball of the hip joint) can occur in children who have endocrine problems and in children who have rapid growth. Any child taking Humatrope who develops a limp or complains of hip or knee pain should be seen by a doctor to check for this.Progression of scoliosis (curvature of the spine) can occur in children who have rapid growth. Humatrope has not been shown to increase the occurrence of this condition.Children with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems while taking Humatrope.You should rotate your injection sites to avoid breakdown of skin and fat. Seek prompt medical attention for any allergic reaction you experience to the injection of Humatrope.If you are pregnant or nursing, you should talk to your doctor before using Humatrope. It is not known whether Humatrope is excreted in human milk. Humatrope should be used during pregnancy only when clearly needed.Clinical studies in patients over 65 years of age have not been done. Elderly patients may be more sensitive to Humatrope and may experience more side effects.Because Humatrope may affect how two hormones, cortisol and cortisone, are processed in the body, people may discover they have hypoadrenalism after starting Humatrope therapy. In these cases, glucocorticoid replacement therapy would need to be started.WHAT ARE THE POSSIBLE SIDE EFFECTS OF HUMATROPE?
Common side effects reported in adults and children taking Humatrope include injection site reactions, allergic reactions to the diluent, and hypothyroidism. Additional common side effects in adults include swelling, joint pain, muscle pain, carpal tunnel syndrome, unusual skin sensations, and high blood sugar. You are encouraged to report negative side effects of prescription drugs to the FDA.
HOW SHOULD I STORE HUMATROPE?Humatrope must be kept refrigerated (36° to 46°F [2° to 8°C]) before and after it is mixed. Do not freeze. Once Humatrope has been mixed and is in liquid form, cartridges must be used within 28 days and vials must be used within 14 days. Throw away any unused Humatrope in a cartridge after 28 days and in a vial after 14 days. Before giving an injection, check the manufacturer’s expiration date on the cartridge or vial. Do not use the cartridge or vial if it has expired.
Esomeprazole Injection 40 mg is powder for solution for infusion/injection contains a medicine called esomeprazole. This belongs to a group of medicines called ‘proton pump inhibitors’. They work by reducing the amount of acid that stomach produces. It is used for the short-term treatment of certain conditions, when patient is unable to have treatment by mouth. It is used to treat Gastro-oesophageal reflux disease(GORD). This is where acid from the stomach escapes into the gullet (the tube which connects throat to stomach) causing pain, inflammation and heartburn. Stomach ulcers (gastric ulcer) caused by medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Esomeprazole can also be used to stop stomach ulcers from forming if patient is taking NSAIDs.
India has many manufacturers who manufacture Esomeprazole Injection 40 mg .To know more contact us.
3s corporation is Supplier, Exporter , Wholesaler for Esomeprazole Injection 40 mg in India.
ADDITIONAL INFORMATION
The usual dose Esomeprazole Injection 40 mg is 20 mg or 40 mg once a day. If patient has severe liver problems, the maximum dose for GORD is 20 mg a day. • The medicine will be given to patient as a slow injection or infusion into one of patient veins. The injection will be given over a period of at least 3 minutes, and the infusion over a period of 10 to 30 minutes. For prevention of re-bleeding gastric or duodenal ulcers, the usual dose is 80 mg administered as intravenous infusion over 30 minutes followed by a continuous infusion dose of 8 mg/hr given over 3 days. If patient has severe liver problems for this indication, a continuous infusion dose of 4 mg/hr given over 3 days may be sufficient.
SIDE EFFECTS
Serious side effects are:
• Sudden wheezing, swelling of lips, tongue and throat or body, rash, fainting or difficulties to swallow (severe allergic reaction).
• Reddening of the skin with blisters or peeling. There may also be severe blisters and bleeding in the lips, eyes, mouth, nose and genitals. This could be ‘Stevens-Johnson syndrome’ or ‘toxic epidermal necrolysis’.
• Yellow skin, dark urine and tiredness which can be symptoms of liver problems.
Other side effects include:
Common (affects less than 1 in 10 people)
• Headache.
• Effects on stomach or gut: diarrhoea, stomach pain, constipation, wind (flatulence).
• Feeling sick (nausea) or being sick (vomiting).
• Injection site reaction.
Uncommon (affects less than 1 in 100 people but more than 1 in 10)
• Swelling of the feet and ankles.
• Disturbed sleep (insomnia).
• Dizziness, tingling feelings such as “pins and needles”, feeling sleepy
• Eyesight problems such as blurred vision.
• Dry mouth.
• Changes in blood tests that check how the liver is working.
• Skin rash, lumpy rash (hives) and itchy skin.
Pantoprazole sodium Injection 40 mg is a Proton Pump Inhibitor (PPI) given by Intravenous use only.It is indicated in treatment of Gastroesophageal Reflux Disease Associated With A History Of Erosive Esophagitis and intreatment of Pathological Hypersecretion Including Zollinger-Ellison Syndrome.
3s corporation is Supplier, Exporter , Wholesaler for Pantoprazole sodium Injection 40 mg in India.
It is manufactured by many Indian manufacturers including Brands like Health biotech etc.
ADDITIONAL INFORMATION
Pantoprazole is not removed by hemodialysis. In case of overdose, treatment should be symptomatic and supportive.
SIDE EFFECTS
Body as a Whole: allergic reaction, fever, photosensitivity reaction, facialedema, thrombophlebitis (I.V. only)
Gastrointestinal: constipation, dry mouth, hepatitis
Hematologic: leukopenia (reported in ex-US clinical trials only), thrombocytopenia
Metabolic/Nutritional: elevated CPK (creatine phosphokinase), generalized edema, elevated triglycerides, liver function tests abnormal
Musculoskeletal: myalgia
Nervous: depression, vertigo
Skin and Appendages: urticaria, rash, pruritus
Special Senses: blurred vision
Kandivali East, Mumbai, Maharashtra