Our Products
We offer a complete product range of CASODEX 50 MG, HISONE 10 MG & 20 MG, SNAKE VENOM ANTI SERUM I.P., PROGYNOVA 1 & 2 MG and EXEMPTIA 40 MG PFS
Casodex also known as ‘bicalutamide’ is an anti-androgen used together with another hormone to treat prostate cancer. This medicine should never be taken by a woman or a child. Although Casodex is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy
Note: Casodex can harm your liver. Call your doctor at once if you have nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
SIDE EFFECTS
Before taking Casodex:
You should not use Casodex if you are allergic to bicalutamide.
Casodex should never be taken by a woman or a child.
Although Casodex is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy.
To make sure this medicine is safe for you, tell your doctor if you have:
EVERTOR™ (Everolimus) is a prescription drug manufactured by Biocon India, indicated for the treatment of patients with advanced renal cell carcinoma (RCC) after failure of treatment with Sunitinib or Sorafenib. It is also popular as the generic version of Afinitor manufactured by Novartis. Its pack size is of 10 tabs. Available in 5 & 10 mg tablet
ADDITIONAL INFORMATION
Hisone is manufactured by Samarth Pharma, India. Hydrocortisone is used to treat many conditions, such as joint problems, severe allergic reactions, certain skin or eye conditions, certain problems with the blood/hormones/immune system, a certain bowel problem (ulcerative colitis), swelling, and worsening multiple sclerosis. Hydrocortisone is a glucocorticoid hormone. It decreases your body’s natural defensive response and reduces symptoms such as redness and swelling.
Dosage :
Most common side effects are Nausea, Rash, Vomiting, Musculoskeletal (bone, muscle or joint) pain, Edema, Abdominal pain, Fatigue, Diarrhoea, Muscle cramp.
Ondansetron Injection USP 4 mg belongs to a group of medicines known as antiemetics and antinauseants being used to prevent vomiting and nausea induced by some medical treatments. Ondansetron Injection can be prescribed for two reasons that is to prevent feelings of sickness (nausea) and sickness (vomiting) and to treat nausea and vomiting.
3s corporation is Supplier, Exporter , Wholesaler for Ondansetron Injection USP 4 mg in India.
We even offer contract manufacturing services from WHO GMP approved factories.
ADDITIONAL INFORMATION
For patients receiving chemotherapy and/or radiotherapy that causes nausea and vomiting:
The recommended dose is 8 mg given by intravenous injection (into a vein) or intramuscular injection (into a muscle), immediately before chemotherapy followed by an 8 mg tablet after 12 hours.
SIDE EFFECTS
Ondansetron Injection USP 4 mg Supplier, Ondansetron Injection USP 4 mg Exporter , Wholesaler Price India
Amphotericin B For Injection I.P. is a freeze dried preparation of Amphotericin B for intravenous injection. It should be administered primarily to patients with progressive, potentially life-threatening fungal infections. Amphotericin B For Injection I.P. should not be administered to treat non-invasive fungal infections such as oral thrush, vaginal candidiasis and oesophageal candidiasis in patients having normal neutrophil counts. It is specifically indicated in the treatment of fungal infections susceptible to Amphotericin B such as the one caused by Candida spp., Aspergillus spp., Crytococcus neoformans, Mucor spp., Rhodotorula spp., Absidia spp., Blastomyces dermatitidis.
It comes in two types liposomal & non-liposomal where the latter is cheaper. It is manufactured in India by many brands like Bharat Serum, Intas, Dabur etc.
ADDITIONAL INFORMATION
The usual daily maintenance dose of Amphotericin B For Injection I.P. is equivalent to 0.5 to 1mg/kg of Amphotericin B. At any given time of administration, a total dose of 1.5mg/kg should never be exceeded.
SIDE EFFECTS
Body as a whole: fever (sometimes accompanied by shaking chills usually occurring within 15 to 20 minutes after initiation of treatment); malaise; weight loss.
Cardiopulmonary: hypotension; tachypnea.
Gastrointestinal: anorexia; nausea; vomiting; diarrhea; dyspepsia; cramping epigastric pain.
Hematologic: normochromic, normocytic anemia.
Local: pain at the injection site with or without phlebitis or thrombophlebitis.
Musculoskeletal: generalized pain, including muscle and joint pains.
Neurologic: headache.
Renal: decreased renal function and renal function abnormalities including: azotemia, hypokalemia, hyposthenuria, renal tubular acidosis; and nephrocalcinosis. These usually improve with interruption of therapy. However, some permanent impairment often occurs, especially in those patients receiving large amounts (over 5 g) of Amphotericin B or receiving other nephrotoxic agents. In some patients hydration and sodium repletion prior to Amphotericin B administration may reduce the risk of developing nephrotoxicity. Supplemental alkali medication may decrease renal tubular acidosis.
Snake Venom Antiserum I.P. is indicated only for the treatment of envenomation caused by bites of the snakes. It is manufactured by Bharat Serum & VINS in India. Snake Venom Antiserum (Polyvalent) is a refined and concentrated preparation of serum globulins obtained by fractionating blood from healthy hyperimmunised horses each ml of which neutralises the following quantities of standard venoms tested in mice by intravenous route.
ADDITIONAL INFORMATIONCAUTION :Snake bite may cause severe tissue damage or fatal envenomation or both. The physician responsible for treatment of the envenomated patient should be familiar with the contents of this pack insert and the medical literature concerning current concepts of first aid and general supportive therapy.
DOSAGE & ADMINISTRATION :DOSAGE :Initial dose depends upon an estimate of the amount of envenomation as mentioned below:1. Minimal Envenomation Progressive local swelling but no systemic symptoms. 5 vials (50ml) isrecommended to be administered.2. Moderate Envenomation Swelling beyond the site of the bite, mild systemic symptoms, and/orhematologic and coagulation abnormalities are present. 5 to 10 vials (50 to 100ml) is recommended to beadministered.3. Severe Envenomation Rapidly progressive and extensive local effects, systemic symptoms andevidence of hemolysis or coagulopathy. 10 to 20 vials (100 200ml) or more is recommended to beadministered.In children and small adults (body weight less than 40kg) upto 50% more doses of Snake VenomAntiserum is recommended to be administered.
ADMINISTRATION :Snake Venom Antiserum is administered intravenously either undiluted at the rate of not more than 1ml per minute or is diluted in 500ml of intravenous fluid (either Sodium Chloride Injection or 5% Dextrose Injection) and administered as rapidly as tolerated over 1-2 hours. While diluting the Snake Venom Antiserum, mix by gentle swirling rather than shaking to avoid foaming. Additional infusions should be repeated hourly until progressive swelling in the bitten part ceases andsystemic signs and symptoms disappear. When an adequate dosage is achieved, the improvement in patients clinical signs are often seen.
IT IS NOT ADVISABLE TO INJECT SNAKE VENOM ANTISERUM AT THE LOCAL SITE OF BITE
Glucored from Sun Pharma Aztec (glibenclamide 2.5 mg, metformin hydrochloride 400 mg.) is an anti-diabetic medicine that helps control blood sugar levels in patients with type 2 diabetes (non-insulin-dependent diabetes). It is a combination of two oral diabetes medicines, Glyburide (Glibenclamide) and Metformin, which works by stimulating the release of your body’s natural insulin. It is used along with a diet and exercise program to lower high blood sugar in patients. By controlling high blood sugar, Glyburide (Glibenclamide)–Metformin helps prevent kidney disease, heart disease, nerve problems, strokes, impotence, and blindness.
Glycomet Tablet (Metformin) from USV is an oral anti-diabetic medicine used to help control blood sugar levels in people with type 2 or non-insulin-dependent diabetes. It belongs to the class of drugs known as biguanides. Metformin is used in combination with a proper diet and exercise program. By controlling high blood sugar, Generic for Glucophage helps prevent kidney damage, loss of limbs, blindness, sexual function problems, and nerve problems.
Glynase XL (Glipizide) tablet from USV is an oral medication used to lower blood glucose levels in type 2 diabetes (non-insulin-dependent diabetes) patients. It belongs to a class of drugs called sulfonylureas, which work by stimulating the pancreas to produce more insulin. Glipizide is used along with diet and exercise to help control blood sugar levels.
ADDITIONAL INFORMATION
How to use Glynase Oral?Read the Patient Information Leaflet if available from your pharmacist before you start taking glyburide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Glyburide comes in different types of tablets which provide different amounts of the medication. Do not switch between different forms or brands of this medication unless directed by your doctor.Take this medication by mouth with breakfast or the first main meal of the day as directed by your doctor, usually once daily. Some patients, especially those taking higher doses, may be directed to take this drug twice a day. The dosage is based on your medical condition and response to treatment.To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.If you are already taking another anti-diabetic drug (such as chlorpropamide), follow your doctor’s directions carefully for stopping the old drug and starting glyburide.If you are also taking colesevelam, take glyburide at least 4 hours before colesevelam.Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.Tell your doctor if your condition does not improve or if it worsens (your blood sugar levels are too high or too low).
SIDE EFFECTS
Nausea, heartburn, stomach fullness, and weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: signs of infection (such as persistent sore throat, fever), easy bleeding/bruising, stomach pain, yellowing eyes/skin, dark urine, unusual tiredness/weakness, unusual/sudden weight gain, mental/mood changes, swelling of the hands or feet, seizures.
pcalis Oral jelly (Tadalafil) is a ver effective treatment for male erectile dysfunction manufactured by Ajanta PharmaApcalis oral jelly starts to work in only 15 minutes due to its liquid form but remains effective for a massive 24-36 hours! The product should be allowed to dissolve in the mouth before it is swallowed.
Uses:
Tadalafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during fore play stimulation.
Apcalis oral jelly often referred to as apcalis jelly works in the same way as Apcalis 20mg tablets. The advantage is that the time to become effective is even quicker at around 20 mins. The sachet also lasts for up to 36 hours allowing users to choose the right time, and again throughout the effective length of the treatment. Which is why Apcalis is sometimes known as the WeekEnder. Side effects are also lower. Apcalis contains 20mg of Tadalafil.
ADDITIONAL INFORMATION
Apcalis Oral Jelly (Tadalafil) Dose ?Apcalis (Tadalafil ) comes as a tablet to take by mouth. It is usually taken with or without food before forepaly activity. Your doctor will help you decide the best time for you to take tadalafil before forepaly activity. Tadalafil should not be taken more often than once every 24 hours.
SIDE EFFECTS
The most common side effects when using tadalafil are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.
Kamagra oral jelly is one of the best known brands globally for generic Viagra in the market. The kamagra 100 mg Oral Jelly contains a drug called Sildenafil citrate available in a gel form that helps treat erectile dysfunction in males. The medication available in a jelly form is more effective and faster acting than the tablet form of the medicine. It is available in 100 mg dosage. Kamagra is also available in 100 mg tablet form. We offer Kamagra Tablets & Jelly at wholesale prices, directly to patients along with EMS & door-to-door delivery options.
How to Use:
To get the best from your treament, please read the following carefully.The safe indicated dose of Kamagra within a 24 hour period is 100mgThis medicine will become effective 1 hour after taking it and effects may be noticeable after 45minsEffective treatment time is 4 – 6 hoursAlways take this medicine with a large glass of waterAvoid large or fatty meals close to when you intend to take the medicineAlcohol will reduce the effectiveness of this medicine.
SIDE EFFECTS
This specific sort of Kamagra 100 online could also demonstrate similar side effects of any kind of tablet presentation of generic Viagra. Examples of these are light headache, exhaustion, level of sensitivity to bright light, dizziness as well as fuzzy view. You don’t have to worry yourself in case you experience most of these Kamagra 100 extra side effects, since they have proven to be actually brief, and they’ll usually appear once you use this particular medicine. But, if you continue to experience any of these signs or symptoms stop its use and also speak to your current healthcare professional to find out if the change in the dosage or perhaps some other generic Viagra medicine could be much better for your health.
About Kamagra tabletsSeveral symptoms should be considered in mind before beginning the treatment with Kamagra 100. It is very important to prevent taking generic Viagra drugs in any of its forms if you take nitrate based drugs. If you’re taking these kinds of medications ensure you first talk to a reliable health practitioner because the interactions between nitrate and sildenafil citrate might seriously cause harm to your health.
SIDE EFFECTS
This specific sort of Kamagra 100 online could also demonstrate similar side effects of any kind of tablet presentation of generic Viagra. Examples of these are light headache, exhaustion, level of sensitivity to bright light, dizziness as well as fuzzy view. You don’t have to worry yourself in case you experience most of these Kamagra 100 extra side effects, since they have proven to be actually brief, and they’ll usually appear once you use this particular medicine. But, if you continue to experience any of these signs or symptoms stop its use and also speak to your current healthcare professional to find out if the change in the dosage or perhaps some other generic Viagra medicine could be much better for your health.
About Kamagra tabletsSeveral symptoms should be considered in mind before beginning the treatment with Kamagra 100. It is very important to prevent taking generic Viagra drugs in any of its forms if you take nitrate based drugs. If you’re taking these kinds of medications ensure you first talk to a reliable health practitioner because the interactions between nitrate and sildenafil citrate might seriously cause harm to your health.
Progynova 1 & 2mg tablets contain oestradiol valerate which is used to replace the loss of oestrogen at menopause to relieve symptoms of menopause. Progynova also stimulates the development of female sexual characteristics for male to female transsexuals in transgender hormone therapy. In India it is sold by Zydus (German Remedies). Pack size of 28 tabs/pack.
ADDITIONAL INFORMATION
What is Progynova used for ;
Progynova tablets 2mg are a hormone replacement therapy (HRT) used to substitute for a lack of oestrogen production by the ovaries that happens during menopause or following surgical removal of the ovaries, to relieve symptoms of menopause caused by oestrogen deficiency, such as hot flushes, night sweats, sleeplessness, vaginal dryness, headaches, mood swings, lack of concentration and loss of energy. Progynova tablets 2mg are also used to help prevent postmenopausal bone loss (osteoporosis) and reduce risk of fracture. Progynova stimulates the development of female sexual characteristics, and is used as the oestrogen component of transgender hormone therapy for male to female transsexuals.
How Progynova works:
Progynova tablets 2mg contain oestradiol valerate, a prodrug (or precursor) of natural human oestradiol, which is the major and most active form of the female sex hormone oestrogen, produced by the ovaries. Oestrogen is a steroid hormone that binds to specific receptors inside oestrogen-responsive cells and stimulates them to make proteins involved in producing female sexual characteristics, such as breast development and in regulating the menstrual cycle. Oestrogen also has several other actions in various metabolic processes including maintaining bone mass and lipid (fat) metabolism.What does Progynova contain?
Progynova contains the active ingredient oestradiol valerate, a prodrug (or precursor) of 17 beta-oestradiol, the major and most active form of oestrogen produced by the ovaries, and is used for hormone replacement therapy (HRT). Progynova also contains lactose monohydrate, maize starch, polyvidone 25 000, talc, magnesium stearate, sucrose, polyvidone 700 000, macrogol 6000, calcium carbonate, glycerol 85%, titanium dioxide, indigo carmine lake, montanglycol waxTreating symptoms of menopause with Progynova
Progynova tablets 2mg are used to treat symptoms caused by a lack of endogenous oestrogen (produced by the ovaries), which happens during menopause, such as hot flushes, night sweats, sleeplessness, vaginal dryness, headaches, mood swings, lack of concentration and loss of energy.
Progynova for hormone replacement therapy:
Progynova 2mg tablets substitute for the loss of oestrogen production by the ovaries that occurs during menopause or following surgical removal of the ovaries. Progynova contains oestradiol, an active form of the female hormone oestrogen that alleviates menopausal symptoms, such as hot flushes, night sweats, sleeplessness, dry vagina, headaches, mood swings, lack of concentration loss of energy and bone loss (osteoporosis).Progynova for transgender treatment
Progynova tablets 2mg can be used as part of a gender reassignment program for male to female transsexuals, by providing a source of oestradiol, the most active form of the female hormone oestrogen. Progynova tablets 2mg stimulate the development of female secondary sexual characteristics, such as breast development and also induce metabolic changes such as fat distribution to redefine the general body shape.
Progynova for feminising hormone therapy:
Progynova tablets 2mg contain oestradiol valerate, a prodrug (or precursor) of natural 17β-oestradiol, the most feminising form of the female hormone oestrogen, which provides a very effective means of feminisation when used as part of a gender reassignment program for male to female transsexuals. Progynova 2mg stimulates the development of female secondary sexual characteristics, such as breast development and also induces metabolic changes such as fat distribution to redefine the general body shape, while at the same time Progynova overrides the effects of testosterone.
SIDE EFFECTS
What are the side effects of Progynova?
The most frequently reported side effects when taking Progynova tablets 2mg are breast tenderness, breast pain, abdominal pain, nausea, oedema, and headache, skin rash and itching, insomnia and depression. More severe side effects include changes in liver function at higher doses and increased risk of dementia if initiated in women aged 65 or older.What are the health risks of Progynova?
Long-term HRT with Progynova does have associated health risks, including an increased risk of breast cancer, endometrial cancer, stroke and deep vein thrombosis. For women with an intact uterus adding a progestogen to an oestrogen replacement regimen like Progynova for at least 10 days per cycle is recommended to reduce the risk of endometrial cancer.When should Progynova not be used?
You should not use Progynova tablets 2mg if you:are allergic to oestradiol valerate or any ingredients in Progynovahave a past or family history of carcinoma of the breast, endometrial carcinoma or liver diseasehave deep venous thrombosis, thromboembolic disorders, cerebral vascular accident associated with oestrogen usehave abnormal genital bleeding of unknown causeare pregnant or planning to become pregnantare taking other medications that may interact with Progynova, such as anticonvulsants like phenytoin and carbamazepin, barbiturates, anti-infectives like rifampicin, rifabutin, nevirapine, antibiotics like penicillin, .are a diabetic taking antidiabetics or insulin, without discussion with your doctor, as Progynova may affect your glucose toleranceHow should Progynova be taken?
You should take Progynova tablets 2mg with a glass of water once a day, preferably at the same time each day, until all 28 tablets have been taken. The dose you take depends on your condition and should be as recommended by your doctor. When you have finished each pack, start the next pack immediately. You can start taking Progynova tablets on any convenient day unless you are still having menstrual bleeding, in which case take the first tablet on day 5 of bleeding.How long should you take Progynova?
Each pack of Progynova tablets 2mg is a calendar pack of 28 tablets. You should take Progynova tablets 2mg for as long as your doctor recommends.Missed dose of Progynova
If you miss a dose of Progynova tablets 2mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. If you forget to take a tablet for more than 12 to 24 hours, irregular bleeding may occur.How should Progynova be stored?
Keep Progynova tablets 2mg in their calendar pack until used. Store at room temperature below 25°C, keep away from direct sunlight and do not refrigerate.
DESCRIPTION
Exemptia 40 mg PFS is a prescription drug manufactured by Cadila (India). It is used inIt is used for the treatment of moderate to severe rheumatoid arthritis (RA). It is a biosimilar version of Humira 40 mg also known as adalimumab. EXEMPTIATM is grouped within a class of medications called biologic response modifiers, or biologics. It works on the immune system, biologics block proteins that contribute to the disease process. Since EXEMPTIATM suppresses the immune system, patients are at a greater risk for getting serious infections.
Its considerably cheaper than the Humira which is manufactured by Abbott & the company claims that it can be available to patients at upto 1/5 the cost of Humira.
ADDITIONAL INFORMATION
Dosing Information:
Administered by subcutaneous injectionDose for Rheumatoid Arthritis (RA), Psoriatic Arthritis, Ankylosing Spondylitis:40 mg every other weekSome patients with RA not receiving methotrexate may benefit from increasing the frequency to 40 mg every week.Dose for Juvenile Idiopathic Arthritis:10 kg to < 15 kg: 10 mg every other week15 kg to < 30 kg: 20 mg every other week≥ 30 kg: 40 mg every other week
How it Works:
Usually, your immune system protects your body from many of the things that can be harmful. But when the immune system doesn’t work properly, it can attack one’s own healthy tissues and organs. This is an autoimmune disorder. A protein called as tumor necrosis factor, also known as TNF, produced naturally by the body is one part of your immune system. But in certain autoimmune diseases, some people produce too much TNF. This often leads to inflammation (Inflammation is the body’s attempt at self-protection; the aim being to remove harmful stimuli, including damaged cells, irritants, or pathogens – and begin the healing process. However, sometimes inflammation can cause further inflammation; it can become self-perpetuating.). EXEMPTIATM (contains adalimumab) is a medication called a TNF blocker. It works by binding to TNF molecules and blocking them from attaching to and attacking healthy cells. In this way, EXEMPTIATM helps reduce the damaging effects of excess TNF. Remember no treatment can stop your body’s overproduction of TNF, but a medication like EXEMPTIATM can help reduce its effects.
The pain, stiffness, and swelling of rheumatoid arthritis can make it difficult for you to perform daily activities such as:Combing your hairButtoning a shirtOpening a jarWalking up stairsFor many adults, EXEMPTIATM is proven to help reduce pain, reduce joint swelling and stiffness, and help stop further joint damage. EXEMPTIATM is a prescription medicine used alone, with methotrexate, or with certain other medicines to reduce the signs and symptoms of moderate to severe rheumatoid arthritis in adults, may prevent further damage to your bones and joints, and may help in increasing your ability to perform daily activities. EXEMPTIATM works by targeting and blocking a specific source of inflammation that contributes to symptoms of rheumatoid arthritis.
RESULTS:
Clinical Trial of EXEMPTIATM in Indian Patients:
Globally Adalimumab is available as HUMIRA. A clinical study was conducted in India to assess if efficacy and safety of EXEMPTIATM is similar to HUMIRA A total 162 subjects were screened at 11 investigational sites in India, of which, 120 subjects were enrolled in the study, 60 subjects in each group viz. EXEMPTIATM and Innovator’s Adalimumab. This trial was conducted for a period of 12 weeks.
How well did EXEMPTIATM work in this trial?
After treatment with EXEMPTIATM, at Visit 5 (on day 84), 82% patients had 20% improvement in rheumatoid arthritis (RA) symptoms, 46% patients had 50% improvement in RA symptoms and 14% patients had 70% improvement in RA symptoms. These results were similar to those with Innovator’s Adalimumab.
How safe was EXEMPTIATM in this trial?
Overall, EXEMPTIATM was safe and well tolerated in this study. The safety profile of both EXEMPTIATM and HUMIRA was similar.
SIDE EFFECTS
What were the commonly observed side- effects with EXEMPTIATM in this trial?
Dyspnoea (difficulty in breathing), Fungal infection, Gastritis, Headache, Injection site reaction, Oligomenorrhoea(menstrual periods occur at intervals of greater than 35 days, with only four to nine periods in a year), Pollakiuria(an excessive frequent urination), Polymenorrhoea (occurrence of menstrual cycles at frequency that is higher than normal), Pulmonary tuberculosis, Fever, Rash, Urinary tract infection, Vomiting, Abdominal discomfort, Abdominal pain, Accelerated hypertension (rapid and sudden increase in blood pressure ), Asthenia (abnormal physical weakness), Chest pain, Cough, Diarrhoea and Dyspepsia (indigestion) Majority of adverse events were mild in intensity and not related to the study drug. There were no persistent changes from baseline in laboratory parameters in both treatment groups.
Floricot 100 mcg tablet also known as Fludrocortisone is a steroid used in hormone replacement therapy for conditions such as Addison’s disease (adrenocortical insufficiency) in which the body does not produce enough natural steroid hormones. These hormones are important in maintaining the balance of certain minerals and water in your body. Its manufactured by Samarth Pharma in India.
Pamidronate Disodium IV Infusion BP 30 mg & 60 mg is used in treatment of moderate to severe hypercalcemia associated with malignancy with or without bone metastases; treatment of moderate to severe Paget disease of bone; treatment of osteolytic bone lesions of multiple myeloma and bone metastases of breast cancer in conjunction with standard chemotherapy.
3s corporation is Supplier, Exporter , Wholesaler for Pamidronate Disodium IV Infusion BP 30 mg & 60 mg in India.
India has many manufacturers who manufacture Pamidronate Disodium IV Infusion BP 30 mg & 60 mg .To know more contact us.
ADDITIONAL INFORMATION
Moderate to Severe Hypercalcemia of Malignancy
Adults
IV For moderate, give 60 to 90 mg as an initial single-dose infusion over 2 to 24 h. For severe, give 90 mg as an initial single-dose infusion over 2 to 24 h. For retreatment, same as initial therapy, at least 7 days after initial dose.
Paget Disease
Adults
IV 30 mg/day as a 4-h infusion on 3 consecutive days for a total dose of 90 mg. For retreatment, same as initial therapy, when clinically indicated.
Osteolytic Bone Metastases of Breast Cancer
Adults
IV 90 mg as a 2-h infusion every 3 to 4 wk.
Osteolytic Bone Lesions of Multiple Myeloma
Adults
IV 90 mg as a 4-h infusion on a monthly basis.
SIDE EFFECTS
Atrial fibrillation; atrial flutter; cardiac failure; hypertension; syncope; tachycardia.
CNSAsthenia; anxiety; fatigue; headache; insomnia; paresthesia; psychosis; somnolence.
DERMATOLOGICSweating.
ENDOCRINEHypothyroidism.
GIAbdominal pain; anorexia; constipation; diarrhea; dyspepsia; GI hemorrhage; nausea; stomatitis; vomiting.
GENITOURINARYUTI; uremia; renal toxicity.
HEMATOLOGIC-LYMPHATICAnemia; granulocytopenia; leukopenia; neutropenia; thrombocytopenia.
LAB TESTSHypocalcemia; hypokalemia; hypomagnesemia; hypophosphatemia.
LOCALInfusion-site reaction.
MUSCULOSKELETALArthralgia; arthrosis; back pain; bone pain; musculoskeletal pain; myalgia; osteonecrosis primarily of the jaws.
RESPIRATORYCoughing; dyspnea; pleural effusion; rales; rhinitis; sinusitis; upper respiratory infection.
MISCELLANEOUSEdema; fever; metastases; moniliasis; pain; allergic manifestations (eg, hypotension, dyspnea, angioedema, anaphylactic shock) .
FLEXBUMIN 20% INFUSION (ALBUMIN HUMAN)
Flexbumin also known as Albumin is a plasma protein which works by increasing plasma volume or albumin level in the blood during surgery, dialysis, abdominal infections, liver failure, pancreatitis, bypass surgery and many other conditions. It is used to replace blood loss due to trauma or any other injuries that caused blood loss.
Dosage :
Hypovolaemia/Shock:
The management of hypovolaemic shock usually requires the IV infusion of at least Albumin-Human 20% 1 L into an average adult patient.
The total volume required cannot be accurately predicted, since it depends on such factors as the initial extracellular fluid volume deficit and the continuing rate of fluid loss.
Hypoproteinaemia in the Acutely Ill Patient :
The usual daily dose is Albumin-Human 20% 50-75 g (Albumex 20 250-375 mL). The rate of administration should not exceed 2 mL/min, as more rapid infusion may precipitate circulatory overload and pulmonary oedema.
The infusion of Albumex 20 is not justified in hypoproteinaemic states associated with chronic cirrhosis, malabsorption, protein losing enteropathies, pancreatic insufficiency or undernutrition.
Shock : The dose should be determined by the patient’s condition and response to treatment. The usual initial dose of Albumin-Human 20% 20 g (Albumex 20 100 mL) may be administered as a blood volume expander at a rate of 2-4 mL/min.
The rate of infusion may be increased in emergencies and repeated in 15-30 min, if necessary. The total dose should not exceed the level of albumin found in the normal individual ie, about 2 g/kg bodyweight in the absence of active bleeding.
If concentrated albumin (>5%) is given, it should be accompanied by the IV infusion of a crystalloid solution. Failure to supply this additional fluid may lead to dehydration of the tissues.
The precise nature and strength of the crystalloid solution will depend on the requirements of the patient for electrolytes and fluid.
Burns : The usual dose is Albumin-Human 20% 20-80 g (Albumex 20 100-400 mL) given daily at the rate of about 1 mL/min.
Beyond 24 hrs, Albumex 20 can be used to maintain plasma colloid osmotic pressure.
A reasonable goal is the maintenance of a plasma albumin concentration of 25 g/L or a colloid osmotic pressure of 20 mmHg. The continuing need for albumin is occasioned by losses from denuded areas and decreased albumin synthesis.
SIDE EFFECTS
Most common side effects are Hypersensitivity reaction, pulmonary edema, weak or shallow breathing, throbbing headache, anxiety, confusion, sweating, pale skin, nausea, vomiting
Pan (Pantoprazole) is a prescription drug used to treat acidity, heartburn, intestinal and stomach ulcers. It reduces amount of acid in the stomach and thereby relieves acid-related indigestion and heartburn.
Dosage :
Usual adult dose when used as antipyretic and analgesic is 500-1000 mg / day (up to 3 g) were divided into 3 admission.
In myocardial infarction, as well as for secondary prevention in patients after myocardial infarction – 40-325 mg 1 time a day (usually 160 mg). As an inhibitor of platelet aggregation – a dose of 300-325 mg / day, for a long time. At the dynamic circulatory disorders in men, cerebral thromboembolism, including to prevent a recurrence – 325 mg / day with gradual increase to a maximum of 1 g / day. For prevention of thrombosis or occlusion of the aortic shunt – by 325 mg every 7 h after intranasal gastric tube set, and then – through the mouth to 325 mg 3 times a day (usually in combination with dipyridamole, which abolished after 1 week, continuing the long-term treatment with Pan).
SIDE EFFECTS
Common side effects are Nausea, Headache, Abdominal pain, Constipation, Flatulence, Diarrhoea.
Fosbait (Lanthanum Carbonate) is a prescription drug used to treat patients with kidney problems and on dialysis. It works by inhibitingthe absorption of phosphate from the intestine and helps in lowering the phosphate levels in the blood.
Dosage :
Most common side effects are Headache, Nausea, Vomiting, Abdominal pain, Flatulence, Constipation, Diarrhoea, Dyspepsia, Decreased calcium level in blood.
Snake Venom Antiserum (Polyvalent) is a refined and concentrated preparation of serum globulins obtained by fractionating blood from healthy hyper-immunized horses. Manufactured by Bharat Serum / VINS, Snake Venom Antiserum I.P. is indicated only for the treatment of envenomation caused by bites of the snakes. We are a prominent Snake Venom Antiserum I.P. Exporter and Supplier from Maharashtra (India). We make our Snake Venom Antiserum I.P. available at affordable prices and in desired quantities.
Each ml of Snake Venom Antiserum (Polyvalent) neutralises the following quantities of standard venoms tested in mice by intravenous route :
Caution :Snake bite may cause severe tissue damage or fatal envenomation or both. The physician responsible for treatment of the envenomated patient should be familiar with the contents of this pack insert and the medical literature concerning current concepts of first aid and general supportive therapy.
Dosage & Administration : Dosage :
Initial dose depends upon an estimate of the amount of envenomation as mentioned below :
In children and small adults (body weight less than 40kg) upto 50% more doses of Snake Venom Antiserum is recommended to be administered.
Administration :Snake Venom Antiserum is administered intravenously either undiluted at the rate of not more than 1ml per minute or is diluted in 500ml of intravenous fluid (either Sodium Chloride Injection or 5% Dextrose Injection) and administered as rapidly as tolerated over 1-2 hours. While diluting the Snake Venom Antiserum, mix by gentle swirling rather than shaking to avoid foaming. Additional infusions should be repeated hourly until progressive swelling in the bitten part ceases and systemic signs and symptoms disappear. When an adequate dosage is achieved, the improvement in patient’s clinical signs are often seen.
Note : It is Not Advisable to Inject Snake Venom Antiserum At the Local Site of Bite
Preservative : Cresol I.P, NMT 0.25% v/v
Arganat 250mg ( Argatroban) is used prevent unwanted blood clots that may occur while receiving heparin in patients who have thrombocytopenia or in those going through angioplasty.
SIDE EFFECTS
Most common side effects are nausea, vomiting, diarrhea, stomach pain, headache , back pain, bleeding around the IV needle, feeling like you might pass out, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin, blood in your urine, black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds, any bleeding that will not stop, pain or burning when you urinate.
Palonosetron 0.25mg Vial is an antiemetic and antinauseant agent.Palonosetron is indicated for
3s corporation is Supplier, Exporter , Wholesaler for Palonosetron 0.25mg Vial in India.
We even offer contract manufacturing services from WHO GMP approved factories.
ADDITIONAL INFORMATION
Dosage for Adults – a single 0.25 mg I.V. dose administered over 30 seconds. Dosing should occur approximately 30 minutes before the start of chemotherapy.
POSTOPERATIVE NAUSEA AND VOMITINGDosage for Adults – a single 0.075 mg I.V. dose administered over 10 seconds immediately before the induction of anesthesia.
SIDE EFFECTS
Get emergency medical help if patient has any of these signs of an allergic reaction:
hives; difficulty breathing; swelling of face, lips, tongue, or throat.
Less serious side effects may include: